Posted on 01/15/2003 7:24:33 AM PST by MrLeRoy
I don't care "how successful" you think they would be. In the scenario shown in the completely idiotic commercial, the girl was at fault, plain and simple.
It amazes me this mentality that alcohol or pot removes any and all ability to avoid a wreck, and if one occurs while the driver was "high" or had been drinking, then the smoke or drink was automatically at fault. It totally ignores the thousands of wrecks that are caused by completely sober people, and the thousands of times an "intoxicated" person drives fine.
Not to mention a very good post to go along with it. Thanks!
AB: Discusses how the psychoactive ingredient in marijuana, Delta9-tetrahydrocannabinol (THC), interferes with short-term memory in both delayed match and delayed nonmatch to sample tasks (DNMS). Animal studies have shown that other cannabinoids, such as the potent cannabinoid receptor (CB1) agonist, WIN 55,212-2 produces a delay-dependent deficit in the DNMS task at a dose range well below that of Delta-sup-9-THC, which was blocked by the CB1 receptor antagonist SR141716A. The effects of WIN 55,212-2 at low doses were similar to those of isolated lesions of the hippocampus, whereas high doses (0.50 mg/kg) produced effects similar to lesions of both hippocampus and surrounding retrohippocampal areas. The low dose effect was delay-dependent while the high dose introduced an additional deficit at short delays that was sensitive to SR141716A and phaclofen. Comparison of lesion vs cannabinoid effects on DNMS performance suggests that CB1 receptors on hippocampal neurons interfere with the processing of DNMS task-specific information within a trial. CB1 receptors on hippocampal gamma-aminobutyric acid (GABA)ergic interneurons and in retrohippocampal areas appear to influence the ability to maintain segregation of information between trials in the task.
(PsycINFO Database
Record (c) 2000 APA, all rights reserved)
AU: Hampson,-Robert-E; Deadwyler,-Sam-A
AF: Wake Forest U, School of Medicine, Dept of Physiology and Pharmacology, Winston-Salem, NC, US
SO: Life-Sciences. 1999 Jul; Vol 65(6-7): 715-723.
JN: Life-Sciences;
PB: US: Elsevier Science, Inc.
IS: 0024-3205
PY: 1999
URLP: www.elsevier.com
LA: English
KP: role of delta-9-THC and cannabinoid receptors in hippocampus in short-term memory interference MJ: *Cannabinoids-; *Hippocampus-; *Neural-Receptors; *Short-Term-Memory; * Tetrahydrocannabinol- MN: Cognitive-Ability; Neurobiology- CC: 2580-Psychopharmacology; 2580; 25 SF: References UD: 19991101
You should write a paper on "The role of anti-drug mania in short-term memory interference"---the subject we were talking about was depression and schizophrenia.
They apparently got weed confused with alchohol...the original date-rape drug.
George Patton: Yes, well that’s the other question that we looked at, and we looked at the extent to which teenage depression predicted frequent cannabis use later on, and what we found is that there was really no relationship there. So cannabis use predicted depression, but depression did not predict frequent daily or even weekly cannabis use.
Norman Swan: What’s the message for young boys in this?
George Patton: It wasn’t that young boys escaped without other problems, and here the link with other mental disorders, particularly psychotic disorders, that link is one that appears to not be gender specific, it’s true for males as well as females.
Norman Swan: So this is the debate which we covered on The Health Report about whether cannabis either brings on a psychotic attack, or in fact causes it in the first place.
George Patton: Well I think that’s right, and all the evidence appears to be pointing in one direction, that cannabis use does cause not only a worse course of schizophrenia but also it does cause higher rates of schizophrenia and the two other papers that appeared in the BMJ were very different studies, both suggesting the same thing. So I think there is the question that the risks are schizophrenia and other psychotic disorders. I think there’s also an important message about the risks for dependence, and in our group we found very high rates of symptoms of dependence, cannabis use, these are symptoms such as withdrawal symptoms, craving for the drug, increased tolerance to cannabis, seeking the drug out, in preference to other social activities, these symptoms were very, very common in daily users, and I think that’s a real problem because I think dependence, whatever the drug, is likely to predict continued use and continued heavy use.
"So cannabis use predicted depression, but depression did not predict frequent daily or even weekly cannabis use."
I didn't mention depression specifically as a predictor; I said, "[The results] can equally well be explained by the theory that the later psychiatric problems are already manifesting themselves in these teens and increasing their propensity to seek out marijuana," i.e., later depression may manifest itself as an earlier psychological condition other than depression. To Patton's credit, he's done some thinking about the causality issue---but he hasn't nearly put it to rest.
Published in the British Medical Journal...
Not all opinions are equal! :)
"...later psychiatric problems are already manifesting themselves ..."
Depressison is a psychiatric problem.
I might add, it's also a societal problem (e.g., effexor and other anti-depressant prescription medications).
But not the only one, so it remains possible that some earlier condition leads to both later depression and later marijuana use.
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