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Rat Joins List of Cloned Animals
Yahoo News ^ | 9/25/03 | Maggie Fox

Posted on 09/25/2003 5:37:06 PM PDT by Libloather

Rat Joins List of Cloned Animals
Thu Sep 25, 4:53 PM ET
By Maggie Fox, Health and Science Correspondent

WASHINGTON (Reuters) - It had to happen. Scientists have finally cloned a rat.

A team of researchers at the Institut National de la Recherche Agronomique in Jouy en Josas, France, and a company called GenOway said on Thursday they had cloned the favored laboratory animal for many researchers, and hope the technology will provide better animals for future research.

"The rat is one of the most widely used animal models in scientific research," GenOway, a company that supplies genetically engineered cell cultures and lab animals, said in a statement.

"Cloning will aid in the development of genetically modified rat models of greater predictability and quality. Scientific results obtained from these models will contribute to the development of innovative therapeutics for major pathologies such as cardiovascular diseases, cancers, obesity, diabetes and neurological disorders."

Rats and mice used in labs are inbred or genetically engineered to have certain traits -- such as a weak immune system, or a tendency to cancer.

So-called knock-out mice and rats lack certain, specific genes and are useful for finding out what an unknown gene does.

Cloning such animals will guarantee they are genetically identical for careful experiments.

Rats, it turns out, are more difficult to clone than sheep, cattle or even mice.

They evolved to reproduce fast and their eggs begin to activate almost as soon as they leave the ovary.

This posed a problem for a technology that requires painstakingly removing an egg cell, taking out its nucleus, and replacing it with the nucleus from a skin or other kind of cell from the animal to be cloned.

Writing in the journal Science, Qi Zhou of INRA and also of the Chinese Academy of Science in Beijing described how they did it.

They impregnated two rats with cloned embryos and produced three live pups, one of which died soon after birth.

They bred the two remaining pups, which fathered normal offspring, and have since cloned two female rats, as well.


TOPICS: Culture/Society; Extended News; News/Current Events
KEYWORDS: animals; cloned; joins; list; rat
They'll have to build a bigger stage for the debates...
1 posted on 09/25/2003 5:37:07 PM PDT by Libloather
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To: Libloather
Say it ain't so.......!!!!
2 posted on 09/25/2003 5:39:09 PM PDT by Lando Lincoln (God Bless the arsenal of liberty.)
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To: Libloather
Why would anyone want to clone a demarat, we have too many already, only the fwench.
3 posted on 09/25/2003 5:39:55 PM PDT by Ethyl
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To: Libloather
Now that they've cloned a rat, they're running it for Governor of California on the GOP line.
4 posted on 09/25/2003 5:40:02 PM PDT by thoughtomator (Right Wing Crazy #5338526)
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To: Libloather
Just what the world needs, more rats. Why don't they clone something useful, like a mink??
5 posted on 09/25/2003 5:41:18 PM PDT by small voice in the wilderness
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To: Libloather
So that is how they get votes and think alike?????
6 posted on 09/25/2003 5:42:15 PM PDT by Cold Heat ("It is easier for an ass to succeed in that trade than any other." [Samuel Clemens, on lawyers])
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To: Libloather
France clones RATS nuff said!
7 posted on 09/25/2003 5:49:50 PM PDT by HuntsvilleTxVeteran (Rush agrees with me 98.5 % of the time.)
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To: Libloather
ALL RIGHT! Maybe this will help cure the world rat shortage...


8 posted on 09/25/2003 5:52:43 PM PDT by pabianice
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To: Libloather
Rat Joins List of Cloned Animals Ye Gods! Come on, scientists! We already have anough lawyers...now you go and make more!
9 posted on 09/25/2003 6:33:10 PM PDT by Orangedog (Soccer-Moms are the biggest threat to your freedoms and the republic !)
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To: Libloather
Please! Tell me it wasn't Hillary!
10 posted on 09/25/2003 6:35:32 PM PDT by gitmo (Zero Tolerance = Intolerance)
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To: Libloather

Twin Sons of Different Mothers

11 posted on 09/25/2003 6:43:44 PM PDT by Samwise (There are other forces at work in this world, Frodo, besides the will of evil.)
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To: Libloather
If you created 10 clones of a Rat, would all ten of them grow up to be Rats?
12 posted on 09/25/2003 7:40:41 PM PDT by norwaypinesavage
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To: Lando Lincoln
Damn, I hope it wasnt Ted Kennedy.

13 posted on 09/25/2003 8:36:32 PM PDT by WOSG (DONT PUT CALI ON CRUZ CONTROL)
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