Speaking of which, Papa gives a blessing at the end, so bring your rosaries, or any sacramental or religious items that you'd want to be blessed.
When you do go to the Vatican Museums, head straight for the Sistine Chapel. Then you can take a more leisurely pace through the rest. I'd go to the Pinacoteca next then to the Museo Pia Cristiano. There's a lot to take in.
We were so blessed to be in the front row. My 4 year old was lifted up to him by one of the security detail and Papa held my boy's face in his hands for a few seconds - and my son was smiling. Can't wait to get the Vatican photos of this.
Rome was a great trip. So very blessed to be able to make such a pilgrimmage. We visited all 4 major basilicas. End of my bragging.