It's in trouble for the secular publishers who have "religious studies" imprints. Ask Ignatius Press if they're in trouble...
Do you know if Ignatius supports itself financially i.e. turns a profit) or if it's supported by grants, etc from the Church?
IMO a publishing firm is only "successful" if it has a market for what it publishes, and can publish w/o suffering a fiscal loss for the effort. Now a financial backer might support the effort because he/she believes in spreading the content to a wider audience, but then IMO the publishing company is actually a ministry, because it's marketing a product for which there is insufficient existing demand to offset costs.
What Ignatius Press has (that HarperCollins lacks) is a discriminating editor, and investors who believe in the editor's vision more than their own wallets. That's not a bad thing, but when someone other than the intended audience ends up footing the bill for such a vision, I'm not sure I would call it "successful".
FWIW, this wasn't meant as an insult to Ignatius Press. I have no idea what their financial status/fiscal model is. I just threw this in to hedge my bets.