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Humans march to a faster genetic 'drummer' than primates, UC Riverside research says
eurekalert.org ^ | 08/30/04 | Kris Lovekin

Posted on 08/31/2004 6:41:31 AM PDT by Michael_Michaelangelo

Humans march to a faster genetic 'drummer' than primates, UC Riverside research says

*Research runs counter to Darwin's theory of natural selection*

A team of biochemists from UC Riverside published a paper in the June 11 issue of the Journal of Molecular Biology that gives one explanation for why humans and primates are so closely related genetically, but so clearly different biologically and intellectually. It is an established fact that 98 percent of the DNA, or the code of life, is exactly the same between humans and chimpanzees. So the key to what it means to be human resides in that other 2 percent.

According to Achilles Dugaiczyk, professor of Biochemistry at UCR, one important factor resides in something called Alu DNA repeats, sometimes called "junk DNA." These little understood sections of DNA are volatile, and prone to sudden mutations, or genomic rearrangements. At times the results are beneficial in that they give rise to new proteins or an altered gene regulation. Sometimes the mutations result in the growth of a cancer tumor, or some other genetic defect.

The team, which also included Rosaleen Gibbons, Lars J. Dugaiczyk, Thomas Girke, Brian Duistermars and Rita Zielinski, identified over 2,200 new human specific Alu DNA repeats that are absent from the chimpanzee and most likely other primates.

"The explosive expansion of the DNA repeats and the resulting restructuring of our genetic code may be the clue to what makes us human," Dugaiczyk said. "During the same amount of time, humans accumulated more genetic novelties than chimpanzees, making the human/chimpanzee genetic distance larger than that between the chimpanzee and gorilla."

Metaphorically speaking, Dugaiczyk said, "Humans and primates march to the rhythm of a drum that looks identical; the same size, shape and sound. But, the human drum beats faster."

This chemical analysis of DNA structures also showed something else. The spread of the Alu DNA repeats was written into the chemistry of human chromosomes. The process was not random, Dugaiczyk said, and it was not subject to an environmental "natural selection," separating winners and losers as theorized by Darwin.

"We are not contending that natural selection does not exist, but that in this instance it is a chemical process within human chromosomes that explains why humans have an explosive expansion of DNA repeats, and primates do not," Dugaiczyk said.

Determining the genetic differences between humans and primates is important for several reasons, Dugaiczyk said, including advancing knowledge about how life developed and evolved on earth. Other benefits include making it easier to identifying human predisposition to genetic disease, by comparing humans with other primate species. A third possible benefit is to underline the importance of protecting endangered primate species.


TOPICS: Culture/Society; Extended News; Miscellaneous; News/Current Events
KEYWORDS: crevolist; darwin; evolution; genetics; godsgravesglyphs; helixmakemineadouble; intelligentdesign; naturalselection; parsimoniousness
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Until now, Alu DNA repeats have been considered "junk dna." The study shows key differences between humans and other primates. The finding is counter to natural selection.

Enjoy!

1 posted on 08/31/2004 6:41:34 AM PDT by Michael_Michaelangelo
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To: LiteKeeper; AndrewC; Elsie; bondserv

Science in action Ping.


2 posted on 08/31/2004 6:42:20 AM PDT by Michael_Michaelangelo
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To: Michael_Michaelangelo

Than how do you explain liberals?


3 posted on 08/31/2004 6:44:12 AM PDT by Shortwave (It's a grown up thing. Libs wouldn't understand.)
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To: Michael_Michaelangelo

"Humans march to a faster genetic 'drummer' than primates"

Uh, humans ARE primates. Maybe someone missed the word "other."


4 posted on 08/31/2004 6:46:01 AM PDT by MineralMan (godless atheist)
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To: MineralMan

Ya think??
5 posted on 08/31/2004 6:50:32 AM PDT by Michael_Michaelangelo
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To: Shortwave

"humans and primates are ...so clearly different biologically and intellectually."
Not all of them, not all.


6 posted on 08/31/2004 6:56:03 AM PDT by GSlob
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To: Michael_Michaelangelo
Question: If Man evolved from Apes, Then why haven't the Apes evolved?
7 posted on 08/31/2004 6:58:05 AM PDT by DirtyHarryY2K (G W B 2004! Friends Don't Let Friends Vote For DemocRATS)
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To: DirtyHarryY2K

To many are 'rats. It has a toxic effect on them.


8 posted on 08/31/2004 7:04:43 AM PDT by sheik yerbouty
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To: Michael_Michaelangelo

Not to mention the different spiritual component.

Humans are created in the image of God (and I contend that means the spiritual realm, not the physical).

Apes, chimps, etc are not "imago Dei".


9 posted on 08/31/2004 7:07:18 AM PDT by fishtank
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To: Michael_Michaelangelo
A change in research perspective will greatly benefit the progress of science! The delay tactics of the hangers-on, has become a pattern of humorous hand waving.

Multispectral Galaxy Studies Contradict Theories   08/27/2004
The latest issue of Caltech’s magazine Engineering and Science1 has beautiful pictures of galaxies taken in ultraviolet by the Galaxy Evolution Explorer (GALEX), and in the infrared by Hubble’s sister, the Spitzer Space Telescope.  Combining images of the same galaxy in visible, ultraviolet and infrared is helping astronomers figure out their structure, and as D. Christopher Martin claims, the origin and evolution of galaxies and stars.  Why, then, at the end of the article, does he say this?

The interesting thing is that the history we have measured completely disagrees with some of the most recent models.   (Emphasis added in all quotes.)
He had just pointed out that “our early results seem to be telling us that star formation was much more vigorous in the past” and that “something has changed very radically about star formation since that time....”
    Whatever; discovery marches on.  “We have found many other interesting things, and we have only just begun to survey the sky.  As our own team and other astronomers explore the data, we look forward to many other discoveries in the future.”
1D. Christopher Martin, “Galaxy Evolution: The View from the Ultraviolet,” Engineering and Science (LXVII:2, 2004), pp. 8-15

Link

10 posted on 08/31/2004 7:07:35 AM PDT by bondserv (Alignment is critical! †)
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To: Michael_Michaelangelo

"We are not contending that natural selection does not exist....."

How is this finding "counter to natural selection", as you claim?


11 posted on 08/31/2004 7:07:57 AM PDT by SCChemist
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To: SCChemist
How is this finding "counter to natural selection", as you claim?

It's not my claim. I quoted from the article.

12 posted on 08/31/2004 7:10:49 AM PDT by Michael_Michaelangelo
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To: bondserv

Excellent article! It should have a thread of it's own.


13 posted on 08/31/2004 7:15:50 AM PDT by Michael_Michaelangelo
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To: Michael_Michaelangelo
Other actual quotes from the article:

Here we trace the evolution of AluYb8 repeats from a single origin at the roots of higher primates to a large increase in their number in humans.

In round numbers, 2200 AluYb8 elements came into existence within about five million years of the human lineage.

Counting only non-CpG mutations (CpG dinucleotides mutate abnormally fast33) gave a total of 2682 mutations/537,072 sites, or 4.99 £ 1023/site. Dividing this number by the rate of change in primate introns of 1.5 £ 1029/site per year,34 yields an estimated age of 3.3 million years for this Alu family. This is in fairly good agreement with the estimated five million years of separation of the human and chimpanzee lineages, but it also indicates that the AluYb8 family was dispersing throughout the entire period of the human lineage.

It's good to see the Creationists endorsing an article supporting the common lineage of humans and other primates and that supports the paleobiological time estimates.

14 posted on 08/31/2004 7:17:36 AM PDT by Doctor Stochastic (Vegetabilisch = chaotisch is der Charakter der Modernen. - Friedrich Schlegel)
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To: Michael_Michaelangelo
The spread of the Alu DNA repeats was written into the chemistry of human chromosomes. The process was not random, Dugaiczyk said, and it was not subject to an environmental "natural selection," separating winners and losers as theorized by Darwin.

I think I saw that episode on the X-Files...

Special creation, anyone?

15 posted on 08/31/2004 7:22:56 AM PDT by valkyrieanne
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To: MineralMan
Uh, humans ARE primates. Maybe someone missed the word "other."

"Primates" is a two syllable series of sounds used to refer to a number of animals that share some characteristics according to criteria assigned to that designation. Because of a belief that human beings are an advanced form of that classification of animals, the term is applied to human beings.

By the human beings who believe they are descended from "primates".

16 posted on 08/31/2004 7:23:59 AM PDT by William Terrell (Individuals can exist without government but government can't exist without individuals.)
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To: martin_fierro; Constitution Day; TheBigB; presidio9

So what's our excuse?


17 posted on 08/31/2004 7:24:43 AM PDT by Tijeras_Slim (W-04!)
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To: Tijeras_Slim; martin_fierro; Constitution Day; presidio9

Whussat? Can't hear you over these damn drums...


18 posted on 08/31/2004 7:27:35 AM PDT by TheBigB (Can I borrow your underpants for ten minutes?)
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To: Tijeras_Slim; TheBigB
So what's our excuse?

My excuse is that my parents made me play with one of these evil things:

Since then, I've had problems with both drummers and primates, but especially creepy primates with cymbals.

19 posted on 08/31/2004 7:34:54 AM PDT by Constitution Day
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bttt


20 posted on 08/31/2004 7:47:59 AM PDT by Professional Engineer (Who knew it would be so much fun to watch a baby learn to grab her toes.)
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