"There may be veiled references to comets in the biblical narrative, leading to the possibility that the Santorini eruption itself may have been triggered by a bolide (comet or asteroid) impact. David Levy, co-discoverer of the comet that bears his and Jean Shoemaker's names, has argued that the description of the angel of the Lord in the sky over Jerusalem with a drawn sword (1 Chronicles 21) could be a reference to a comet."
"The Angel of the Lord was, of course, also present at the Exodus, as it was traveling in front of Israel's army. Further, there are indications that as the Israelites left Egypt, the night was as bright as midday.
Other than there having been just one ancient, historic eruption of Thera, around 200 BC... ;’)
The Santorini/Thera volcano was about 1626 BC, so it was too early. However, Etna blew a big one at 1500 BC plus or minus 50 years. Personally, I think the pillar of fire by night and smoke by day was volcanic in nature. Note the recent eruption in the Red Sea. A lot more work has to be done on Middle East volcanism, dates, etc.