I wanted to update myself about adjuvants, so here's the section from IMMUNIZATION taught to second year students at the University of South Carolina School of Medicine.
Weaker antigens may be rendered more immunogenic by the addition of other chemicals. Such chemicals are known as adjuvants. There are many biological and chemical substances that have been used in experimental conditions (Table 1). However, only Aluminum salts (alum) are approved for human use and it is incorporated in DTP vaccine. Furthermore, pertussis itself has adjuvant effects. Adjuvants used experimentally include mixtures of oil and detergents, with (Freunds complete adjuvant) or without certain bacteria (Freunds incomplete adjuvant). Bacteria most often used in an adjuvant are Mycobacteria (BCG) and Nocardia. In some instance sub-cellular fractions of these bacteria can also be used effectively as adjuvants. Newer adjuvant formulations include synthetic polymers and oligonucleotides. Most adjuvants recognize TOLL-like receptors thus activating mononuclear phagocytes and inducing selective cytokines that can enhance Th1 or Th2 responses, depending on the nature of the adjuvant.
A quarter of the way scrolling down from the top is a link at that site to the vaccine section. I haven't read that yet.
I've seen some paranoid comments about adjuvants, but this administration has a habit of causing paranoid reactions.
Thanks for posting this .
In an advanced Microbiology class I was taking I had to go research adjuvants. In the deep recesses of Buehler Hall at the University of Tennessee I found the original research by Koch in the German microbiological periodicals. Koch used adjuvants in many of the first vaccines against the Clostridials which are in use today. BCG and aluminum salts were in use in the 1890’s!!