I do love over-kill. I have .380 ACP hydra-shok. And bannan-clip 7.62 Ruger mini-14 with hollow-point as back up. All locked and loaded.
That’s a Ruger ranch rifle - looks like a mini-14 though. And the M-16 round is .223 but will go through cinder-blocks laughing all the way. Size matters, but energy delivered to the target is also in the velocity. Energy goes up as the square of the velocity. It’s only proportional to the mass.