[Bronzewound]

...some of us carry a recessive gene for dilution of melanin...

What is the diluting agent for melanin? I want to know what additional substance is inside me. I may withdraw a small portion and study it.

Maybe there's a market for it.

[bert]

Melanin content in ocular tissues of both the strains was determined by sodium hydroxide solubilization method. The affinity of celecoxib to synthetic and natural melanin was estimated by co-incubating celecoxib and melanin in isotonic phosphate-buffered saline. The binding affinity (k) and the maximum binding (rmax) for celecoxib to both natural and synthetic melanin were estimated. Suspension of celecoxib (3 mg/rat) was injected periocularly into one eye of Sprague-Dawley (SD, albino) and Brown Norway (BN, pigmented) rats. The animals were euthanatized at the end of 0.25, 0.5, 1, 2, 3, 4, 8, or 12 hours after the drug was administered, and celecoxib levels in ocular tissues (sclera, choroid-RPE, retina, vitreous, lens, and cornea) were estimated with an HPLC assay. In addition, celecoxib-poly(lactide) microparticles (750 μg drug/rat) were administered periocularly in SD and BN rats, and celecoxib levels in these eye tissues were assessed on day 8, to determine the effectiveness of the sustained release system.

[John S Mosby]

You’re too late. Michael Jackson already found it. However, now he’s gone the supply has recovered somewhat. Dilute is like Beirut— you know Beirut? He wuz a pretty good ball player.