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Apparent Immunity Gene ‘Cures’ Bay Area Man Of AIDS
CBS San Francisco ^ | May 16, 2011 12:25 PM | Staff

Posted on 05/17/2011 6:20:20 AM PDT by Red Badger

SAN FRANCISCO (CBS 5) — A 45-year-old man now living in the Bay Area may be the first person ever cured of the deadly disease AIDS, the result of the discovery of an apparent HIV immunity gene.

Timothy Ray Brown tested positive for HIV back in 1995, but has now entered scientific journals as the first man in world history to have that HIV virus completely eliminated from his body in what doctors call a “functional cure.”

Brown was living in Berlin, Germany back in 2007, dealing with HIV and leukemia, when scientists there gave him a bone marrow stem cell transplant that had astounding results.

“I quit taking my HIV medication the day that I got the transplant and haven’t had to take any since,” said Brown, who has been dubbed “The Berlin Patient” by the medical community.

Brown’s amazing progress continues to be monitored by doctors at San Francisco General Hospital and at the University of California at San Francisco medical center.

“I’m cured of HIV. I had HIV but I don’t anymore,” he said, using words that many in the scientific community are cautiously clinging to.

Scientists said Brown received stem cells from a donor who was immune to HIV. In fact, about one percent of Caucasians are immune to HIV. Some researchers think the immunity gene goes back to the Great Plague: people who survived the plague passed their immunity down and their heirs have it today.

UCSF’s Dr. Jay Levy, who co-discovered the HIV virus and is one of the most respected AIDS researchers in the world, said this case opens the door to the field of “cure research,” which is now gaining more attention.

“If you’re able to take the white cells from someone and manipulate them so they’re no longer infected, or infectable, no longer infectable by HIV, and those white cells become the whole immune system of that individual, you’ve got essentially a functional cure,” he explained.

UCSF’s Dr. Paul Volberding, another pioneering AIDS expert who has studied the disease for all of its 30 years cautioned that while “the Berlin Patient is a fascinating story, it’s not one that can be generalized.”

Both doctors stressed that Brown’s radical procedure may not be applicable to many other people with HIV, because of the difficulty in doing stem cell transplants, and finding the right donor.

“You don’t want to go out and get a bone marrow transplant because transplants themselves carry a real risk of mortality,” Volberding said.

He explained that scientists also still have many unanswered questions involving the success of Brown’s treatment.

“One element of his treatment, and we don’t know which, allowed apparently the virus to be purged from his body,” he observed. “So it’s going to be an interesting, I think productive area to study.”

Volberding continued, “Knock on wood, (Brown) hasn’t had any recurrence now for several years of the virus, and that hasn’t happened before in our experience.”

As a result, at the San Francisco AIDS Foundation some are now using the word “cure” after so many avoided it for decades.

“You sort of felt like you couldn’t say ‘cure’ for a number of years. Scientists and clinicians and people with HIV alike felt that was a promise that was never going to be realized and it was dangerous to direct a lot of energy toward it,” said Dr. Judy Auerbach. “And now things have shifted.”

The California Institute of Regenerative Medicine is currently funding stem cell research in the Bay Area based on Brown’s case in the hopes of replicating his success for broader populations of people with HIV.

The institute said it plans to begin clinical trials next year.


TOPICS: Culture/Society; US: California
KEYWORDS: aids; cure; health; hiv; timothyraybrown

1 posted on 05/17/2011 6:20:26 AM PDT by Red Badger
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To: Red Badger

Not to sound flippant, but how long before he contracts another case?


2 posted on 05/17/2011 6:25:43 AM PDT by Puppage (You may disagree with what I have to say, but I shall defend to your death my right to say it)
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To: Puppage

If the article is correct about the effect... never.


3 posted on 05/17/2011 6:28:37 AM PDT by Bigh4u2 (Denial is the first requirement to be a liberal)
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To: Puppage

My question, too.
But, if he has an ‘immunity’ to the virus from the bone marrow transplant, then it must be able to destroy the virus when it enters the body...........


4 posted on 05/17/2011 6:28:57 AM PDT by Red Badger (Jesus said there is no marriage in Heaven. That's why they call it Heaven............)
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To: Red Badger

He may be immune now....who knows?


5 posted on 05/17/2011 6:31:12 AM PDT by Jessica2677 (S.O.S.)
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To: Red Badger

A 45-year-old man now living in the Bay Area may be the first person ever cured of the deadly disease AIDS, the result of the discovery of an apparent HIV immunity gene.

The story is a lie.

Ann Wigmore has cured AIDS I met a man who was cured. BUT the Medical Field will not allow anyone to be a CURED person if they do NOT do it through Traditional medicine that costs Millions of dollars!


6 posted on 05/17/2011 6:35:17 AM PDT by chicagolady (Mexican Elite say: EXPORT Poverty Let the American Taxpayer foot the bill !)
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To: Red Badger
This is awesome news! Now, anyone who has contracted the disease through irresponsible, high-risk behavior can now live a consequence-free lifestyle.

/s

7 posted on 05/17/2011 6:35:17 AM PDT by edpc (I disagree. Circle gets the square.)
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To: chicagolady
I thought Magic Johnson was cured.
8 posted on 05/17/2011 6:37:14 AM PDT by MPJackal ("From my cold dead hands.")
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To: Jessica2677

This is the Delta-32 mutation, and it also giver the person immunity to the black death.

I think HIV is a retrovirus. If so, a person could have every single one of the viruses in their body be gone and still be infected.

Retroviruses are sneaky suckers. They “splice” their own DNA into your own personal cellular DNA. Then they may or may not croak.

At some point in time, for whatever reason, sometimes your own cells start copying the new DNA and they (re)produce NEW COPIES OF THE VIRUS.

So now all the sudden, you are re-infected.


9 posted on 05/17/2011 6:42:30 AM PDT by djf ("Life is never fair...And perhaps it is a good thing for most of us that it is not." Oscar Wilde)
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To: edpc
Now, anyone who has contracted the disease through irresponsible, high-risk behavior can now live a consequence-free lifestyle.

They already do. It's called "bug hunting" and those perverted freaks in san fran have been doing it for some time.

10 posted on 05/17/2011 6:42:43 AM PDT by LouAvul
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To: edpc

Wait a minute. How the helk do you know he practiced irresponsible behavior? They said he also had leukemia. He may have contracted the disease through a blood transfusion.


11 posted on 05/17/2011 6:47:32 AM PDT by EnquiringMind
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To: Red Badger

Hooray! The miracles of modern medicine will allow this deviant to pack fudge without a care! The “cure” to this disease is to not put your pecker where it shouldn’t be.


12 posted on 05/17/2011 6:47:32 AM PDT by 762X51
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To: MPJackal

Why? Was his Johnson Magic?............


13 posted on 05/17/2011 6:55:07 AM PDT by Red Badger (Jesus said there is no marriage in Heaven. That's why they call it Heaven............)
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To: EnquiringMind

You’re hearing/reading what you want to. I never said he did or didn’t. However, there are those who do. I was pretty definitive.


14 posted on 05/17/2011 7:19:37 AM PDT by edpc (I disagree. Circle gets the square.)
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To: EnquiringMind
He may have contracted the disease through a blood transfusion.

That would explain his move to San Francisco. /sarc/

15 posted on 05/17/2011 7:38:44 AM PDT by aimhigh (True bitter clingers cling to their guns AND their bibles.)
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To: aimhigh

He may have moved to SF because of the interest in his medical case.


16 posted on 05/17/2011 9:07:19 AM PDT by newzjunkey (Obama will be president until 2017.)
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