Netanyahu has been saying this for many years, at least back when George W. Bush was president, and possibly back to Clinton's days if not earlier.
I'm fairly sure I remember the Iranians calling America the “Great Satan” all the way back when Jimmy Carter was president, but that was long ago and maybe my memory is flawed.
Moderate Muslims may be nice people, but the Islamofascists who rule much of the Middle East are sworn enemies of America and American values. The main difference between America and Israel is the Israelis understand what they're fighting and too many of our people don't.
Let's give credit where credit is due, however... at least President Obama told the Iranians that he'll act if they go nuclear. It would be nice if he would do more, but my guess is he's given the Iranians a clear warning that Israel has the green light to go ahead since Obama knows Netanyahu is a credible threat.
More effective than taking out the plants, is the “sudden deaths” of several Iranian nuclear scientists!