It’s not his turn anyway. Next up to lose is Jeb. The GOPe’s are already pushing his name out there.
It also seems that Hillary is declining (at present, but may change her mind later). If she does not run, that opens the way for another youthful Democrat to run against the Bush name, especially is Jeb is on the ticket. Win Win for the Dems.
The conservatives will chase after a half-dozen candidates who will hang on long enough to split the primary votes and give Jeb the nomination. Repeat of 2008 and 2012.
It doesn't matter anyway. The Democrats have it all locked up for the foreseeable future. The GOP is dead and we have no major party to represent us. C'est le vie.