Free Republic
Browse · Search
News/Activism
Topics · Post Article

Skip to comments.

News In Brief: Fructose may be key to weight gain
www.sciencenews.org ^ | September 9, 2013 | By Nathan Seppa

Posted on 09/10/2013 12:44:32 PM PDT by Red Badger

Mice that could not make or metabolize the sugar gained less than normal mice.

Mice lacking the ability to metabolize fructose don’t gain nearly as much weight as normal mice do, researchers report September 10 in Nature Communications.

Fructose, which some people blame for the obesity epidemic and its related health crises (SN: 6/1/13, p. 22), shows up in high-fructose corn syrup and in table sugar, or sucrose. The body also makes home-grown fructose by modifying glucose in a process involving an enzyme called aldose reductase.

(Excerpt) Read more at sciencenews.org ...


TOPICS: Business/Economy; Culture/Society
KEYWORDS: cornsyrup; fructose; hfcs; nutrition; obesity; sugar; type2diabetes
Navigation: use the links below to view more comments.
first previous 1-2021-4041-55 next last
To: NativeSon; Paradox
Although glucose can be metabolized by every cell in the body, fructose is metabolized almost entirely by the liver. There it can result in the generation of free radicals (damaged cells that can damage other cells) and uric acid (which can lead to kidney disease or gout), and it can kick off a process called de novo lipogenesis, which generates fats that can find their way into the bloodstream or be deposited on the liver itself. These byproducts are linked to obesity, insulin resistance and the group of risk factors linked to diabetes, heart disease and stroke. (Lustig gives a detailed explanation of fructose metabolism in a well-viewed YouTube video called "Sugar: The Bitter Truth.")

http://www.freerepublic.com/focus/f-chat/3065106/posts

21 posted on 09/10/2013 1:30:07 PM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
[ Post Reply | Private Reply | To 14 | View Replies]

To: Red Badger

Another one of those useless ‘studies’.


22 posted on 09/10/2013 1:33:13 PM PDT by I want the USA back
[ Post Reply | Private Reply | To 1 | View Replies]

To: 9YearLurker

breakdown - destruction of the monomer or clip the linkages?


23 posted on 09/10/2013 1:33:35 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
[ Post Reply | Private Reply | To 19 | View Replies]

To: I want the USA back

Stay healthy, eat your honey...


24 posted on 09/10/2013 1:41:01 PM PDT by refermech
[ Post Reply | Private Reply | To 22 | View Replies]

To: Red Badger
These byproducts are linked to obesity, insulin resistance and the group of risk factors linked to diabetes, heart disease and stroke

Regardless of the biochemical pathways, Fructose is found in plants, as with many other compounds found in nature, we are "designed" to process it...

The end of those reactions produce molecules critical to our function. Like cholesterol, cholesterol is fantastic, without it, well, say good by to bi-lipid membranes for starters...

The issue here is dosage- stop stuffing your gob with anything that resembles an edible and most of the "modern problems" will clear up.

25 posted on 09/10/2013 1:44:14 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
[ Post Reply | Private Reply | To 21 | View Replies]

To: 9YearLurker
man/woman analogy. I use it to cover chemisty topics with non chemists. See, fructose is not a component of sucrose, you will never boil/steam/filter/sift it out. Just like the word "man" is in "woman" does mean that you can extract the man...

um, unless in San Fran or Thailand... but I digress.

26 posted on 09/10/2013 1:48:39 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
[ Post Reply | Private Reply | To 18 | View Replies]

To: NativeSon

Still a wacky analogy.

But lots of components can’t be boil/steam/filter/sifted out of things.


27 posted on 09/10/2013 2:14:35 PM PDT by 9YearLurker
[ Post Reply | Private Reply | To 26 | View Replies]

To: NativeSon

Here ya go:

“When fructose is consumed in the form of sucrose, it is digested (broken down) and then absorbed as free fructose. As sucrose comes into contact with the membrane of the small intestine, the enzyme sucrase catalyzes the cleavage of sucrose to yield one glucose unit and one fructose unit, which are then each absorbed.”

http://en.wikipedia.org/wiki/Fructose


28 posted on 09/10/2013 2:18:28 PM PDT by 9YearLurker
[ Post Reply | Private Reply | To 23 | View Replies]

To: NativeSon

29 posted on 09/10/2013 3:04:53 PM PDT by MCH
[ Post Reply | Private Reply | To 2 | View Replies]

To: Red Badger

People drank soda since it was invented but after the switch from real sugar to corn syrup, bad things seemed to happen.

Sugar tasted better too.


30 posted on 09/10/2013 3:06:24 PM PDT by GeronL
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger

Having been into amateur body building a long time ago, I have known about the problems with fructose long before its recent infamy. Sucrose include fructose, so too much of that is a bad thing too.


31 posted on 09/10/2013 4:25:35 PM PDT by Paradox (Unexpected things coming for the next few years.)
[ Post Reply | Private Reply | To 21 | View Replies]

To: texas booster
He really wrote this? Fructose shows up in Sucrose?

And this guy is a science writer?

One who knows better than to piss off Big Corn - thus softening the blow with, "Sugar causes it, too." :)

32 posted on 09/10/2013 4:29:30 PM PDT by Mr. Jeeves (CTRL-GALT-DELETE)
[ Post Reply | Private Reply | To 9 | View Replies]

To: GeronL
People drank soda since it was invented but after the switch from real sugar to corn syrup, bad things seemed to happen.

Funny, I prefer the taste of corn syrup (100% glucose) to sugar (sucrose which is metabolized to 50% glucose and 50% fructose). You might be confused and instead mean "high-fructose corn syrup" which is normal corn syrup catalyzed to about 55% fructose and 42% glucose. This ratio, incidentally, is the same as natural honey. The only real difference between natural honey and synthetic high fructose corn syrup is the traces of pollen in the honey.

33 posted on 09/10/2013 4:39:27 PM PDT by Ronaldus Magnus
[ Post Reply | Private Reply | To 30 | View Replies]

To: 9YearLurker
Now that - enzymatic cleavage- is what happens. Still doesn't mean that it is bad for you but you do get "2 for price of one" out of it.

if you have any interest, pick up a biochemistry text, truly amazing to understand some of the chemistry of our bodies.

here's an interesting biochem tip- if you happen to drink a wee bit much, drink something with a lot of glucose (or sucrose) before going to bed. For the extra credit, why?

34 posted on 09/10/2013 8:03:35 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
[ Post Reply | Private Reply | To 28 | View Replies]

To: 9YearLurker
But lots of components can’t be boil/steam/filter/sifted out of things.

a mixture can be separated by mechanical/physical means. So the sugar in 'grape drank' can separated by boiling off the aqueous portion and crystalizing the sugar. The sugar molecule however will remain unchanged.

or in biology, I can spin your blood down and separate the solids and the bits but the oxygen bonded to your prosthetic group of the porphyrin rings will remain chemically bonded.

35 posted on 09/10/2013 8:13:12 PM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
[ Post Reply | Private Reply | To 27 | View Replies]

To: NativeSon

You’re giving me the tutorial now?


36 posted on 09/10/2013 11:32:42 PM PDT by 9YearLurker
[ Post Reply | Private Reply | To 34 | View Replies]

To: 9YearLurker

Just sharing my enjoyment of chemistry ...


37 posted on 09/11/2013 3:17:23 AM PDT by NativeSon ( Grease the floor with Crisco when I dance the Disco)
[ Post Reply | Private Reply | To 36 | View Replies]

To: GeronL

Oddly, Mexico does not allow HFCS to be used in soft drinks, raw sugar only. Big Lots sells some Mexican soft drinks, including imported Coca-Cola! You can get that old-fashioned taste for about a dollar a bottle (yes they are still in the old green glass Coke bottles!)...............


38 posted on 09/11/2013 6:28:55 AM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
[ Post Reply | Private Reply | To 30 | View Replies]

To: Paradox

Too much of anything can be bad for you, health-wise, but HFCS should be very limited intake........


39 posted on 09/11/2013 6:30:39 AM PDT by Red Badger (It is dangerous to be right in matters where established men are wrong. .....Voltaire)
[ Post Reply | Private Reply | To 31 | View Replies]

To: Red Badger

They keep reusing those bottles.


40 posted on 09/11/2013 6:30:49 AM PDT by GeronL
[ Post Reply | Private Reply | To 38 | View Replies]


Navigation: use the links below to view more comments.
first previous 1-2021-4041-55 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
News/Activism
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson