Advances In "Micro" RNA Exploring Process Of Life

Science Daily ^ | 9/23/2002

[LiteKeeper]

read later

[balrog666]

Do you have a biogenetics ping list?

[PatrickHenry]

RNA world ping.

[js1138]

Before it's pulled bump.

[general_re]

"Before it's pulled"? Oh, ye of little faith... ;)

[VadeRetro]

"Mark for later" bump.

[js1138]

Is gravity low today? The science threads are dying of natural causes. Of course they are way over my head and don't have any sexy immediate implications.

[JediGirl]

The science threads are dying of natural causes. Of course they are way over my head and don't have any sexy immediate implications.

Kinda like this thread?

Underage and selling their sexuality on the Web :P

[general_re]

Is gravity low today?

Depends on where you are...

[RightWhale]

OSU was recently the recipient of a 4-year, $1.7 million grant from the National Science Foundation

This would be the reason for the article. A little PR. Publish or perish.

[tallhappy]

Here us the actual abstract from the Science article

Science 2002 Sep 20;297(5589):2053-6



Cleavage of Scarecrow-like mRNA targets directed by a class of
Arabidopsis miRNA.

Llave C, Xie Z, Kasschau KD, Carrington JC.

Center for Gene Research and Biotechnology, and Department of Botany and Plant Pathology,
Oregon State University, Corvallis, OR 97331, USA.

Micro-RNAs (miRNAs) are regulatory molecules that mediate effects by interacting with
messenger RNA (mRNA) targets. Here we show that Arabidopsis thaliana miRNA 39 (also
known as miR171), a 21-ribonucleotide species that accumulates predominantly in inflorescence
tissues, is produced from an intergenic region in chromosome III and functionally interacts with
mRNA targets encoding several members of the Scarecrow-like (SCL) family of putative
transcription factors. miRNA 39 is complementary to an internal region of three SCL mRNAs.
The interaction results in specific cleavage of target mRNA within the region of complementarity,
indicating that this class of miRNA functions like small interfering RNA associated with RNA
silencing to guide sequence-specific cleavage in a developmentally controlled manner.

[r9etb]

Well, the science threads wouldn't be dying if they all referred to cleavage.

Cleavage of Scarecrow-like mRNA targets...

Scarecrow cleavage -- better than nothing, I guess.....

[tallhappy]

Science threads die because a bunch of ignorant religious zealots turn it in to some sort of proselyization for their evolutionist religion.

It turns interesting threads in to boring beat-a-dead-horse threads.

[tallhappy]

Also, how much is there to say? These miRNA's are great findings and indicate a new way to regulate gene expression. It is a fine tuning of the system and the extent of it is still hardly known.

In this system, it is quite interesting that the genes they are regulating by cleavage are themselves transcription factors -- ie they themselves are genes that regulate gene expression.

It's a quick way to turn off the genes regulated by scarecrows.

[r9etb]

I find that cleavage piques my interest in genetic expression....

(OK, so I'm in the gutter again.)

[balrog666]

Science threads die because a bunch of ignorant religious zealots turn it in to some sort of proselyization for their evolutionist religion.

Well, thanks for kicking things off, Mr Shortgrumpy!

[Aric2000]

Science threads die because a bunch of ignorant religious zealots turn it in to some sort of proselyization for their evolutionist religion.


I am sure that you actually meant to say.....

Science threads die because a bunch of ignorant religious zealots turn it in to some sort of prostelyization for their Creationist myth.

Oops, there I went and did it.

[Condorman]

You realize, of course, that this discovery totally refutes evolution.