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"Binary" Enzyme Created By Scripps Scientists Demonstrates Darwinian Evolution At Its Simplest
Scripps Research Institute / ScienceDaily News ^ | 12/19/2002 | John S. Reader, D.Phil, and Professor Gerald F. Joyce, M.D., Ph.D

Posted on 12/19/2002 5:57:50 AM PST by forsnax5

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To: PatrickHenry
The creationoid empire is similar to the socialist empire -- it's built upon ignorance -- their own and that of their followers.

Had I thought of that term, I think I would have removed two of those letters.

41 posted on 12/19/2002 12:41:01 PM PST by balrog666
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To: PatrickHenry
The creationoid empire is similar to the socialist empire -- it's built upon ignorance -- their own and that of their followers

No offense, but evolutionists have the smug attitude of "ours is science while yours is no better than magic, suckers." Well there is some point to that. But if you wrap yourself in a cloak of science you should live by the rules of science, and they say that gaps in the evidence taint your conclusions and cast doubt on them until you fill them. You may not like that, but if you choose to ignore that part of the scientific method then you have abandoned it. As for the "creationoids", they dont have the same burden of proof since they readily acknowledge their worldview is based on faith which cannot be proved or disproved. When scientists take the same attitude, a new religion is founded. So it seems in case of evolution.

42 posted on 12/19/2002 12:41:29 PM PST by pepsi_junkie
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To: forsnax5
Thanks for the ping. Fun chemistry. Good just-so stories.

From Nature

Using just two bases, Reader and Joyce mimicked the R3 ligase ribozyme, a stretch of RNA that latches onto another RNA molecule.

Part of the R3 ribozyme has a base sequence that matches that on its RNA target molecule. The researchers constructed this binding sequence and target from A and U bases alone.

Then, for technical reasons, they replaced the A's with a non-natural base called diaminopurine (D). The resultant ribozyme can be copied without the need for G or C bases. Copying is a necessary part of the process of finding a two-letter mimic.

The researchers then eliminated all of the G's that they could from the R3 molecule while still retaining some of its catalytic behaviour (it can manage without C's). All but three could go; if the researchers took any of those out, the molecule was no longer catalytic.

To get further, the researchers abandoned rational design and turned to in vitro evolution. They replaced the remaining G's at random with U or D, while shuffling a few of the other U's and D's in the molecule.

None of the products made this way is a particularly stunning catalyst. But they work. The best, containing just U and D, links to the RNA target 36,000 times faster than in the absence of any catalyst at all. In other words, a two-letter ribozyme is a lot better than nothing.

D isn't too difficult to create from the kind of ingredients that were probably available on the early Earth, say Reader and Joyce. They also point out the advantage of an RNA-like molecule that contains no C: cytosine decomposes quite quickly if it gets warm.


43 posted on 12/19/2002 1:03:35 PM PST by AndrewC
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To: pepsi_junkie
There really is not proof that it ever happened.

Actually, there is no way to prove that yesterday happened.

44 posted on 12/19/2002 3:28:34 PM PST by Lessismore
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To: Lessismore
Yesterday didn't happen. We of the Church of Last Thursday believe that the universe was created on Thursday (that's today) by the lord of the cats, Queen Maeve. When the end time comes (probably next Thursday, but there is some dispute on that matter), those who have been exceptionally nice to cats will become cats and live on Mars to be served as human slaves. Those who simply lead 'good' lives, but who are not exceptionally nice to cats will become human slaves to cats on Mars (though they will be treated well) and those who are cruel to cats will be cast into the Eternal Litterbox, which is never emptied.

Now when do we get our creation theory taught as alternative science in Ohio public schools?!
45 posted on 12/19/2002 4:22:18 PM PST by Dimensio
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To: Dimensio
Heretic!

All true believers are followers of the Cargo Cult and the Prophet John Frum (Blessing Be Upon Him!), and they know that the Universe was created when it fell out of the cargo hatch of an R4D flying over the Solomon Islands!

46 posted on 12/19/2002 4:26:20 PM PST by Poohbah
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To: pepsi_junkie
A "God of the Gaps" placemarker.
47 posted on 12/19/2002 4:56:16 PM PST by Junior
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To: pepsi_junkie
Well, since water can run uphill, why can't the development of organisms? All you need is a few billion years, sunshine and a lot of luck. Want to by stock in
Blind Watchmaking Inc.?
48 posted on 12/19/2002 5:51:24 PM PST by metacognative
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To: jlogajan
Seriously, what makes these chemicals organize? It is not physico-chemical laws. What is reading the DNA code?
49 posted on 12/19/2002 5:56:18 PM PST by metacognative
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To: PatrickHenry
add me to list please, thanks
50 posted on 12/19/2002 6:01:28 PM PST by visualops
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To: metacognative
Seriously, what makes these chemicals organize? It is not physico-chemical laws. What is reading the DNA code?

Have you ever looked at a magnified view of a snowflake? Very organized (yet rather spontaneous) structure that repeats in small ways that grow into a larger structure.

Crystalization is very definately "chemical" in nature. It has structure, it has reproducibility (from the small scale to the large.) Yet we attribute no magic behind it, no purpose, no goal, no "reader", no "intelligent designer."

DNA and other life forms are really just an ongoing crystalization process, if you will.

51 posted on 12/19/2002 6:20:03 PM PST by jlogajan
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To: PatrickHenry
Placemarker.
52 posted on 12/19/2002 7:15:03 PM PST by PatrickHenry
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To: jlogajan
DNA and other life forms are really just an ongoing crystalization process, if you will.

Bull.

53 posted on 12/19/2002 8:17:54 PM PST by AndrewC
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To: AndrewC
Bull.

Thanks for the Biblical quote.

54 posted on 12/19/2002 8:38:13 PM PST by jlogajan
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To: jlogajan
Isn't that what the Pope said the Marty Luther?
55 posted on 12/19/2002 8:58:32 PM PST by Doctor Stochastic
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To: jlogajan
DNA and other life forms are really just an ongoing crystalization process, if you will.

Kind of like claiming that New York city is just a sort of an exxagerated ant colony...

Real experts have noted that RNA and DNA are vastly beyond the level of complexity at which something could just sort of happen.

56 posted on 12/19/2002 9:01:22 PM PST by titanmike
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To: titanmike
Real experts have noted that RNA and DNA are vastly beyond the level of complexity at which something could just sort of happen.

So, are these "real experts" claiming RNA and DNA didn't happen?

Or are they "experts" in believeing the scientific musings of ancient goat herders?

57 posted on 12/19/2002 9:11:00 PM PST by jlogajan
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To: jlogajan
You are quite welcome. It fits your "science".
58 posted on 12/19/2002 9:25:35 PM PST by AndrewC
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To: jlogajan
One often-quoted case:

"At that moment, when the DNA/RNA system became understood, the debate between Evolutionists and Creationists should have come to a screeching halt

I.L. Cohen, Researcher and Mathematician
Member NY Academy of Sciences
Officer of the Archaeological Inst. of America
Darwin Was Wrong - A Study in Probabilities
New Research Publications, 1984, p. 4

I gather from reading that mathematicians as a group are less than fond of evolutionism. Something about dealing with logic on a regular basis...

59 posted on 12/19/2002 9:41:44 PM PST by titanmike
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To: titanmike
I gather from reading that mathematicians as a group are less than fond of evolutionism.

Hmmm, yeah, sounds unanimous. heh heh

60 posted on 12/19/2002 10:23:31 PM PST by jlogajan
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