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Keyword: adultstemcells

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  • A Better Way to Reprogram Cells

    10/01/2010 6:00:36 PM PDT · by neverdem · 6 replies
    ScienceNOW ^ | 30 September 2010 | Gretchen Vogel
    Enlarge Image New fate. Applying synthetic RNA for a muscle master-control gene turns embryonic cells into muscle cells. Credit: Warren et al., Cell Stem Cell, Advance Online Publication (2010) Four years ago, scientists took a major step toward overcoming the biggest ethical hurdle in stem cell research. Instead of using cells derived from embryos, researchers found a way to make adult cells behave as though they were embryonic. Simply inserting extra copies of four genes into these cells gave them the power to develop into almost any cell type in the bodya potential boon for studying and ultimately treating...
  • Stem Cell Research: Adults Only?

    08/24/2010 6:23:34 PM PDT · by Kaslin · 2 replies
    IBD Editorials ^ | August 24, 2010 | Investors Business Daily staff
    Bioethics: A federal judge rules that the administration violated congressional intent when it lifted restrictions on federal funding for embryonic stem cell research. No, this will not usher in a new dark age. The ruling by U.S. District Judge Royce Lamberth was striking enough. Lamberth said that when President Obama lifted Bush administration restrictions on ESCR, he violated the Dickey-Wicker Amendment. First passed in 1996, and passed every year as part of the federal budget, Dickey-Wicker blocks federal funds for stem cell research in which human embryos are destroyed. Perhaps more striking is the press coverage of Lamberth's ruling. The...
  • Human neural stem cells restore motor function in mice with chronic spinal cord injury

    08/19/2010 2:07:49 PM PDT · by decimon · 15 replies
    University of California, Irvine ^ | August 19, 2010 | Unknown
    UCI study is first to show reversal of long-term hind-limb paralysisA UC Irvine study is the first to demonstrate that human neural stem cells can restore mobility in cases of chronic spinal cord injury, suggesting the prospect of treating a much broader population of patients. Previous breakthrough stem cell studies have focused on the acute, or early, phase of spinal cord injury, a period of up to a few weeks after the initial trauma when drug treatments can lead to some functional recovery. The UCI study, led by Aileen Anderson and Brian Cummings of the Sue and Bill Gross Stem...
  • Playing Politics with Stem Cells

    08/08/2010 11:25:37 AM PDT · by neverdem · 6 replies
    American Thinker ^ | August 08, 2010 | By Gene Tarne and David Prentice
    When scientists play politics with science, society and science both suffer, sometimes with life-threatening implications.  One recent example is Climategate, with revelations that leading global warming researchers played with the data, concealed and tried to suppress data that challenged their assertions and attempted to game the peer-review system.  And as a result of scientists caught playing politics with science, claims of man-made global warming have been met with growing skepticism. But a similar scenario has played out regarding human embryonic stem cell research (hESCR),  With the introduction of legislation to codify the Obama administration's rules expanding the federal role in...
  • Wishing him well

    08/02/2010 12:33:56 AM PDT · by kathsua · 6 replies · 3+ views
    The Hutchinson News ^ | 07/31/10 | Kathy Hanks
    GREAT BEND - Beth Schneweis can see herself dashing after her young son, Christopher, as he runs off the airplane when they return from Germany this fall. Wednesday morning she was laughing out loud as she described the image that plays often in her mind. The sounds of his mother chuckling caused 5-year-old Christopher, strapped into his specially designed tilt chair, to roll his head toward her and smile. The idea of Christopher, who has cerebral palsy, walking off an airplane in a few months, after having additional stem cells injected into his spine at a clinic in Germany, is...
  • Scientists develop 'fake' genetically-engineered blood for use on the battlefield

    07/10/2010 9:09:20 PM PDT · by neverdem · 41 replies
    Daily Mail, ^ | 10th July 2010 | Niall Firth
    American scientists have developed 'artificial' blood that could soon be used to treat wounded soldiers in battle.The genetically-engineered blood is created by  taking cells from umbilical cords and using a machine to mimic the way bone marrow works to produce mass quantities of usable units of red blood cells.Known as 'blood pharming' the programme was launched in 2008 by the Pentagon's experimental arm, Darpa, to create blood to treat soldiers in far-flung battlefields. The firm Arteriocyte, which received $1.95 million for the project, has now sent off its first shipment of O-negative blood to the food and drugs watchdog in...
  • Stem cells from blood a 'huge' milestone (May prove easier/faster than other harvesting methods)

    07/06/2010 9:27:29 AM PDT · by SeekAndFind · 12 replies · 1+ views
    Science News ^ | 07/06/2010 | Laura Sanders
    Blood drawn with a simple needle stick can be coaxed into producing stem cells that may have the ability to form any type of tissue in the body, three independent papers report in the July 2 Cell Stem Cell. The new technique will allow scientists to tap a large, readily available source of personalized stem cells. Because taking blood is safe, fast and efficient compared to current stem cell harvesting methods, some of which include biopsies and pretreatments with drugs, researchers hope that blood-derived stem cells could one day be used to study and treat diseases though major safety...
  • Rats Breathe With Lab-Grown Lungs

    07/01/2010 10:49:44 PM PDT · by neverdem · 9 replies · 1+ views
    ScienceNOW ^ | June 24, 2010 | Mitch Leslie
    Enlarge Image Lung "skeleton." The underlying air passages (left) and blood vessels (right) remain after lungs are decellularized. Credit: Petersen et al., Science For the first time, an animal has drawn a breath with lungs cultivated in the lab. Although preliminary, the results might eventually lead to replacement lungs for patients. People whose lungs are failing because of diseases such as emphysema or cystic fibrosis face a grim outlook. Only 10% to 20% of patients who undergo lung transplants survive for 10 years, versus about 50% for heart recipients. Research to create new lungs in the lab has lagged...
  • Surface chemistry helps direct stem cell fate

    04/30/2010 6:21:10 PM PDT · by neverdem · 4 replies · 220+ views
    Highlights in Chemical Biology ^ | 30 April 2010 | Andrew Kirk
    UK scientists have developed a method to control the behaviour and fate of stem cells using chemically-defined nanopatterned surfaces. This could aid development of tissues and organs for transplants.Stem cell research offers limitless opportunities to develop new medical therapies, such as growing organs and tissues in the lab for transplantation into humans. The ability to reproducibly control cultures of stem cells is very important to avoid variation in clinical trials but the lack of consistency in the material on which the cells are grown has so far made this difficult. Also, current methods used to control stem cell behaviour, such...
  • Stem cells find their polystyrene niche

    03/31/2010 8:09:50 PM PDT · by neverdem · 3 replies · 230+ views
    Highlights in Chemical Biology ^ | 29 March 2010 | Laura Howes
    Norwegian scientists have developed a microfluidic platform to grow stem cells outside of the body in a controlled manner for a period of three weeks.Stem cells from bone marrow are known as mesenchymal stem cells (MSCs) and like all adult stem cells they survive in specific microenvironments within the body, known as niches. But it's not so easy to grow them outside the body as they spread out as they grow which makes it difficult to control their microenvironment in vitro, as they tend to inhabit and block feeding channels. Previous microfluidic systems using glass substrates use hazardous chemicals to...
  • Jaw Bone Grown from Adult Stem Cells

    03/31/2010 2:02:48 PM PDT · by saganite · 11 replies · 447+ views
    Science Daily ^ | Mar. 31, 2010 | staff
    A Columbia scientist has become the first to grow a complex, full-size bone from human adult stem cells. Gordana Vunjak-Novakovic, a professor of biomedical engineering at the Fu Foundation School of Engineering and Applied Science, reports that her team grew a temporomandibular joint (TMJ) from stem cells derived from bone marrow. Her work is reported in the online Early Edition of the journal Proceedings of the National Academy of Sciences this month. "The TMJ has been widely studied as a tissue-engineering model because it cannot be generated easily, if at all, by current methods," says Vunjak-Novakovic, whose co-authors include Warren...
  • Research Offers Clue Into How Hearts Can Regenerate in Some Species

    03/25/2010 12:24:33 AM PDT · by neverdem · 3 replies · 402+ views
    NY Times ^ | March 24, 2010 | NICHOLAS WADE
    Doctors who have treated heart attack patients with injections of stem cells have had little success so far in making the heart regenerate its stricken tissues. Researchers have now discovered that in nature, hearts are regenerated in a quite different way, one that does not depend on stem cells. The finding may explain the lack of clinical success with the stem cells, as well as suggest new approaches. Humans can regenerate the liver but cannot replace limbs and other organs. But fish and... --snip-- Charles Murry, an expert on heart cell biology at the University of Washington in Seattle, said...
  • Breakthrough reveals blood vessel cells are key to growing unlimited amounts of adult stem cells

    03/04/2010 2:56:49 PM PST · by decimon · 6 replies · 259+ views
    Promises broad clinical benefits, from bone marrow transplantation to therapies for heart, brain, skin and lungsNEW YORK (March 4, 2010) -- In a leap toward making stem cell therapy widely available, researchers at the Ansary Stem Cell Institute at Weill Cornell Medical College have discovered that endothelial cells, the most basic building blocks of the vascular system, produce growth factors that can grow copious amounts of adult stem cells and their progeny over the course of weeks. Until now, adult stem cell cultures would die within four or five days despite best efforts to grow them. "This is groundbreaking research...
  • Stem cell experiment reverses aging in rare disease

    02/17/2010 1:05:18 PM PST · by decimon · 10 replies · 366+ views
    Reuters ^ | Feb 17, 2010 | Maggie Fox
    WASHINGTON (Reuters) In a surprise result that can help in the understanding of both aging and cancer, researchers working with an engineered type of stem cell said they reversed the aging process in a rare genetic disease. The team at Children's Hospital Boston and the Harvard Stem Cell Institute were working with a new type of cell called induced pluripotent stem cells or iPS cells, which closely resemble embryonic stem cells but are made from ordinary skin cells. In this case, they wanted to study a rare, inherited premature aging disorder called dyskeratosis congenita. The blood marrow disorder resembles...
  • Stem cells rescue nerve cells by direct contact

    02/01/2010 2:44:06 PM PST · by decimon · 4 replies · 290+ views
    Karolinska Institutet ^ | Feb 1, 2010 | Unknown
    Scientists at the Swedish medical university Karolinska Institutet have shown how transplanted stem cells can connect with and rescue threatened neurons and brain tissue. The results point the way to new possible treatments for brain damage and neurodegenerative diseases. A possible strategy for treating neurodegenerative diseases is to transplant stem cells into the brain that prevent existing nerve cells from dying. The method has proved successful in different models, but the mechanisms behind it are still unknown. According to one hypothesis, the stem cells mature into fully-mature neurons that communicate with the threatened brain tissue; according to another, the stem...
  • California's Proposition 71 Failure

    01/12/2010 5:53:07 PM PST · by Kaslin · 20 replies · 1,728+ views ^ | January 12, 2010 | INVESTORS BUSINESS DAILY Staff
    Bioethics: Five years after a budget-busting $3 billion was allocated to embryonic stem cell research, there have been no cures, no therapies and little progress. So supporters are embracing research they once opposed. California's Proposition 71 was intended to create a $3 billion West Coast counterpart to the National Institutes of Health, empowered to go where the NIH could not either because of federal policy or funding restraints on biomedical research centered on human embryonic stem cells. Supporters of the California Stem Cell Research and Cures Initiative, passed in 2004, held out hopes of imminent medical miracles that were...
  • Stem Cell as Anti-Aging "Medicine" - Recent Findings Support Need for Maintaining Stem Cell Health

    01/03/2010 2:02:58 PM PST · by neverdem · 18 replies · 1,294+ views
    Medistem Inc. via Marketwire ^ | Dec 28, 2009 | NA
    Recent Findings Support Need for Maintaining Stem Cell HealthSAN DIEGO, CA--(Marketwire - December 28, 2009) - Medistem Inc. (PINKSHEETS: MEDS). In a collaborative publication, a group of scientists theorized that a special type of stem cell circulating in the blood stream, called the "endothelial progenitor cell," may be a critical factor in maintaining a long and healthy life. This was followed up with human data demonstrating the food supplement Stem-Kine increased the numbers of these cells in circulation. The paper, entitled "Circulating Endothelial Progenitor Cells: A New Approach to Anti-Aging Medicine?" synthesized current research in the area of age-associated deterioration...
  • A 'fountain of youth' for stem cells?

    12/28/2009 11:52:17 AM PST · by decimon · 4 replies · 358+ views
    University of Hong Kong ^ | Dec 28, 2009 | Randolph Fillmore
    Tampa, Fla. (December 28, 2009) Researchers from the University of Hong Kong and the Massachusetts Institute of Technology have published a study in the current issue of Cell Transplantation (18:9), now freely available on line at, that explores ways to successfully keep stem cells "forever young" during implantation by slowing their growth, differentiation and proliferation. "The successful storage and implantation of stem cells poses significant challenges for tissue engineering in the nervous system, challenges in addition to those inherent to neural regeneration," said Dr. Ellis-Behnke, corresponding author. "There is a need for creating an environment that can regulate...
  • Stem Cell Glue Saves Climber's Leg

    12/16/2009 7:56:42 AM PST · by GonzoII · 10 replies · 719+ views
    Sky News ^ | December 16, 2009 | Thomas Moore
    A climber who was warned he faced the amputation of a limb has had his leg saved by a new stem cell technique. Andrew Kent broke his leg so badly while rock climbing in the Lake District that traditional surgery failed. For the first time in Britain, doctors then used his own stem cells to heal the bones in a technique they believe could revolutionise orthopaedic operations. "I've got a good prognosis. I'm very pleased with the way things have turned out," Mr Kent told Sky News. He and his son were climbing in the Langdale Pikes earlier this year...
  • MS sufferer walks after stem cell treatment

    12/15/2009 8:24:53 AM PST · by Nachum · 18 replies · 1,171+ views
    Telegraph UK ^ | 12/15/09 | Bonnie Malkin
    An Australian man who was confined to a wheelchair by multiple sclerosis has made a remarkable recovery after receiving a groundbreaking stem cell treatment. Ben Leahy, 20, was diagnosed with the disease in 2008 and lost the ability to stand within a few months. However, a new procedure to combat the disease has helped him regain his health and he is now walking again.