Keyword: autoimmune

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  • US-Cuba handshake brings smiles at Biocon

    07/24/2015 11:16:17 PM PDT · by Jyotishi · 1 replies
    Daily News & Analysis ^ | Saturday, July 25, 2015 | Soumonty Kanungo
    Drug maker says better poised to licence and position its novel molecule Itolizumab, which has a Cuban origin Mumbai - Bangalore-based Biocon hopes that the thaw in bilateral relations between the US and Cuba offers the company a "better opportunity" to licence and partner its novel molecule Itolizumab, used for the treatment of psoriasis. The molecule, which has a Cuban origin, is the world's first novel anti CD-6 monoclonal antibody to treat multiple autoimmune diseases. The drug was launched in India in 2013 under the brand name Alzumab. "Itolizumab is advancing well. With relations restored between Cuba and the...
  • Skin drug shows 'promising' results on type 1 diabetes

    09/22/2013 5:14:00 PM PDT · by Innovative · 4 replies
    BBC ^ | Sept 22, 2013 | BBC
    A drug that was used to treat a skin disorder has shown signs of being able to treat aspects of type 1 diabetes. A small trial on US patients suggests that alefacept helps the body produce its own insulin, which is key for people with type 1 diabetes.
  • Breakthrough nanoparticle halts multiple sclerosis

    11/21/2012 11:41:34 PM PST · by LibWhacker · 21 replies
    EurekAlert! ^ | 11/18/12 | Marla Paul
    New nanotechnology can be used for Type 1 diabetes, food allergies and asthma New nanoparticle tricks and resets immune system in mice with MSFirst MS approach that doesn't suppress immune systemClinical trial for MS patients shows why nanoparticle is best optionNanoparticle now being tested in Type 1 diabetes and asthma CHICAGO --- In a breakthrough for nanotechnology and multiple sclerosis, a biodegradable nanoparticle turns out to be the perfect vehicle to stealthily deliver an antigen that tricks the immune system into stopping its attack on myelin and halt a model of relapsing remitting multiple sclerosis (MS) in mice, according...
  • Researcher contends multiple sclerosis is not a disease of the immune system

    12/22/2011 3:19:09 PM PST · by decimon · 11 replies
    An article to be published Friday (Dec. 23) in the December 2011 issue of The Quarterly Review of Biology argues that multiple sclerosis, long viewed as primarily an autoimmune disease, is not actually a disease of the immune system. Dr. Angelique Corthals, a forensic anthropologist and professor at the John Jay College of Criminal Justice in New York, suggests instead that MS is caused by faulty lipid metabolism, in many ways more similar to coronary atherosclerosis (hardening of the arteries) than to other autoimmune diseases. Framing MS as a metabolic disorder helps to explain many puzzling aspects of the disease,...
  • Intestine crucial to function of immune cells, research shows (MS? RA?)

    12/12/2011 6:28:36 PM PST · by decimon · 20 replies
    University of Toronto ^ | December 12, 2011
    TORONTO, Canada—Researchers at the University of Toronto have found an explanation for how the intestinal tract influences a key component of the immune system to prevent infection, offering a potential clue to the cause of autoimmune disorders like rheumatoid arthritis and multiple sclerosis. "The findings shed light on the complex balance between beneficial and harmful bacteria in the gut," said Prof. Jennifer Gommerman, an Associate Professor in the Department of Immunology at U of T, whose findings were published online by the scientific journal, Nature. "There has been a long-standing mystery of how certain cells can differentiate between and attack...
  • Rituximab Trial Shows Promise (ME/CFS, Chronic Fatigue Syndrome is autoimmune disorder?)

    10/30/2011 6:20:15 PM PDT · by Seizethecarp · 20 replies
    Research1st ^ | October 19, 2011 | K. Kimberly McCleary
    A study published on Oct. 19, 2011, in PLoS ONE reports on results of a double-blind, placebo-controlled trial of the drug rituximab in CFS. The results of this study showing that two infusions of rituximab may provide durable relief from CFS are extremely encouraging. The most exciting news from the study is the possibility of disease-modifying treatment for at least some people with CFS. This study also provides support for other possible approaches to repair immune abnormalities that have been identified in CFS patients. The authors state that the results support the concept of CFS as an autoimmune disease. They...
  • Glucosamine-like supplement suppresses multiple sclerosis attacks (autoimmune diseases)

    09/30/2011 12:41:16 PM PDT · by decimon · 2 replies
    UCI study shows promise of metabolic therapy for autoimmune diseasesA glucosamine-like dietary supplement suppresses the damaging autoimmune response seen in multiple sclerosis, according to a UC Irvine study. UCI’s Dr. Michael Demetriou, Ani Grigorian and others found that oral N-acetylglucosamine (GlcNAc), which is similar to but more effective than the widely available glucosamine, inhibited the growth and function of abnormal T-cells that in MS incorrectly direct the immune system to attack and break down central nervous system tissue that insulates nerves.
  • Low-dose naltrexone (LDN): Tricking the body to heal itself

    09/04/2011 8:21:54 PM PDT · by decimon · 23 replies
    Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered the mechanism by which a low dose of the opioid antagonist naltrexone (LDN), an agent used clinically (off-label) to treat cancer and autoimmune diseases, exerts a profound inhibitory effect on cell proliferation. It has been postulated that opioid receptor blockade by LDN provokes a compensatory elevation in endogenous opioids and opioid receptors that can function after LDN is no longer available. Using a novel tissue culture model of LDN action, the mechanism of LDN has been found to target the opioid growth factor (OGF, [Met5]-enkephalin) and OGF...
  • Mechanism discovered for health benefit of green tea, new approach to autoimmune disease

    06/02/2011 12:40:16 PM PDT · by decimon · 20 replies
    Oregon State University ^ | June 2, 2011 | Unknown
    CORVALLIS, Ore. – One of the beneficial compounds found in green tea has a powerful ability to increase the number of “regulatory T cells” that play a key role in immune function and suppression of autoimmune disease, according to new research in the Linus Pauling Institute at Oregon State University. This may be one of the underlying mechanisms for the health benefits of green tea, which has attracted wide interest for its ability to help control inflammation, improve immune function and prevent cancer. > In this study, OSU scientists did experiments with a compound in green tea, a polyphenol called...
  • A Unifying Theory of Autoimmune Disease

    05/25/2011 2:10:48 PM PDT · by neverdem · 20 replies
    Harvard Medical School ^ | May 5, 2011 | NA
    Carbohydrate activates B cells in skin, connective tissues Researchers led by HMS Associate Professor of Medicine Julia Wang offer a new, unifying theory on the origins of autoimmune diseases. In two related papers in the May 2011 issue of the American Journal of Pathology, the team outlines a process by which a carbohydrate abundant in skin and connective tissue called dermatan sulfate turns traitorous. The resulting disease may be systemic, as in lupus or rheumatoid arthritis, or localized, as in Type 1 diabetes or Graves’ disease. Only a tiny subset of molecules in the body are known to have the...
  • How The Humble Hydrangea Shrub Could Hold The Key To Curing MS, Diabetes and Arthritis

    06/04/2009 10:36:17 PM PDT · by Steelfish · 53 replies · 2,736+ views
    June 04, 2009
    How the humble hydrangea shrub could hold the key to curing MS, diabetes and arthritis By FIONA MACRAE 05th June 2009 It's bright and beautiful flowers bring a splash of colour to gardens all over Britain. But it seems the hydrangea is more than just a pretty bloom. A drug made from its roots could be used to treat a raft of common diseases, researchers say. The colourful shrub - a staple of Chinese medicine - has the power to 'revolutionise' the treatment of multiple sclerosis, psoriasis and some forms of diabetes and arthritis, scientists claimed yesterday. Hydrangea: The common...
  • Female Marines give up locks for love

    12/31/2008 3:48:11 PM PST · by SandRat · 39 replies · 6,645+ views
    Marine Corps News ^ | Cpl. Aaron Rooks, USMC
    MARINE CORPS BASE CAMP LEJEUNE, N.C. (Dec. 30, 2008) — Two Female Marines from the 2nd Marine Logistics Group came together this holiday season to donate more than 26 inches of hair to financially disadvantaged children. Cpl. Kendra Hernandez, a legal clerk with Headquarters and Service Company, Combat Logistics Regiment 27, 2nd MLG, and Cpl. Kimberly Pike, an administrative clerk with the 2nd MLG Administrative Section, cut off 14 and 12 inches of their hair respectively to give to Locks for Love. The non-profit organization provides hair pieces to children under the age of 18 who suffer from long-term medical...
  • Hope for safer bone marrow transplants

    11/26/2007 7:54:23 PM PST · by Coleus · 108+ views
    Guardian News ^ | November 23 2007 | Ian Sample
    Patients with common immune disorders such as multiple sclerosis and rheumatoid arthritis could one day be treated with bone marrow transplants, scientists claimed yesterday. Hopes for the new treatment follow the development of a more efficient transplant technique which avoids the need for radio- or chemotherapy, both of which have potentially dangerous side-effects. Traditional bone marrow transplants are used to treat only life-threatening conditions, such as leukaemia or lymphoma. The treatment infuses healthy adult stem cells into the patient, which then form fresh blood and immune cells. But before the transplant can be done, patients must receive a course of...
  • Researchers Explain Why Having Baby Reduces Breast Cancer Chances

    10/07/2007 9:01:50 PM PDT · by monomaniac · 7 replies · 495+ views ^ | October 2, 2007 | Steven Ertelt
    by Steven EditorOctober 2, 2007Seattle, WA ( -- Researchers at a cancer center in Seattle have confirmed what previous studies have shown: women who bear children have a reduced risk of developing breast cancer. They say fetal cells “transplanted” to the mother before birth are a source of this protective effect. That's something that abortion denies.Scientists at the University of Washington and Fred Hutchinson Cancer Research Center presented their results in the October 1 issue of Cancer Research, a journal of the American Association for Cancer Research.They studied a concept called fetal microchimerism, which is the ability of cells...
  • Create A Back-Up Copy Of Your Immune System

    06/22/2007 5:37:05 PM PDT · by blam · 5 replies · 534+ views
    New Scientist ^ | 6-22-2007 | Andy Coghlan
    Create a back-up copy of your immune system 22 June 2007 news service Andy Coghlan Imagine having a spare copy of your immune system on ice, ready to replace your existing one should you fall victim to AIDS, an autoimmune disease, or have to undergo extensive chemotherapy for cancer. An Anglo-American company called Lifeforce has received permission from the US Food and Drug Administration to do just that. The firm collects 480-millilitre samples of blood from healthy individuals, extracts the white blood cells and stores them as an insurance policy against future disease. The service comes at a price,...

    12/09/2005 4:09:03 AM PST · by TheSentry · 2 replies · 518+ views
    SEATTLE POST-INTELLIGENCER ^ | Dec. 1st, 2005 | Pete Yost (AP writer)
    SEATTLE POST-INTELLIGENCER Thursday, December 1, 2005 · Last updated 10:01 a.m. PT _Anthrax shots may be required in military_ By PETE YOST ASSOCIATED PRESS WRITER * WASHINGTON -- The Bush administration asked a federal appeals court Thursday to reinstate mandatory anthrax inoculations for many military personnel, while a lawyer for soldiers who refused the shots said anti-anthrax vaccine was never intended for the purpose the Pentagon is using it. * The government is appealing a decision by U.S. District Judge Emmet Sullivan, who suspended anthrax vaccinations after he found fault in the Food and Drug Administration's process for...
  • Severe immune response kills SARS victims

    05/02/2003 8:39:46 AM PDT · by CathyRyan · 76 replies · 297+ views news service ^ | May 3, 2003 | Robert Walgate
    An excessive immune reaction appears to be the fatal factor in patients who die of SARS, according to medical data from Hong Kong. The best estimate of the fatality rate of SARS is rising steadily and so understanding how the disease causes death is critical to finding the best treatments. Scientists have also discovered that the SARS virus can remain viable for at least 24 hours after being deposited in a droplet on a plastic surface - a simulation, for example, of an infected person coughing on to the wall of a lift. The new information was revealed by Klaus...