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Keyword: cornea

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  • Ulster scientists in breakthrough which could end curse of hereditary blindness (N. Ireland)

    09/12/2015 2:02:32 AM PDT · by Olog-hai · 4 replies
    Belfast Telegraph ^ | 09/11/2015 | Laura Abernethy
    Ulster University scientists have made a remarkable breakthrough which it is hoped could cure hereditary blindness. They have discovered a treatment that can target the gene that leads to corneal dystrophy—a condition that causes cloudy deposits on the cornea. […] Currently, those with corneal dystrophy face a lifetime of treatment and the only option for those who go blind is a corneal transplant from a donor eye, but this has risks and varying success rates. […] But the new treatment, developed by scientists at the University’s School of Biomedical Science, currently involves just one injection into the eye, which destroys...
  • Researchers regrow corneas using adult human stem cells

    07/03/2014 7:40:26 AM PDT · by Olog-hai · 5 replies
    Fox News ^ | July 02, 2014 | Loren Grush
    Boston researchers have successfully regrown human corneal tissue—a feat that could potentially restore vision in the blind. The achievement also marks one of the first times that scientists have constructed tissue using adult-derived human stem cells. In a new study published in the journal Nature, researchers from Massachusetts Eye and Ear Institute, Boston Children’s Hospital, Brigham and Women’s Hospital and the VA Boston Healthcare System detailed their groundbreaking research. According to the paper, the key to the study’s success revolves around a molecule known as ABCB5, which serves as a biomarker for previously elusive limbal stem cells. Residing in the...
  • Scientists discover brand-new body part

    06/14/2013 11:22:30 AM PDT · by rickmichaels · 33 replies
    National Post ^ | JUNE 14, 2013
    Embedded in your eye is a body part that until recently, no one knew existed.
  • Lab made cornea offers new hope for restored vision

    08/25/2010 12:11:36 PM PDT · by decimon · 4 replies
    BBC ^ | August 25, 2010 | Pamela Rutherford
    Corneas made in the laboratory have successfully restored the sight of 10 Swedish patients with significant vision loss.Produced entirely from synthetic collagen, the implants offer the tantalising possibility for a replacement to human donor tissues. The custom-made corneas work by prompting regeneration of the nerves and cells in the eye. This is the first time vision has been restored in this way. > The patients all recovered their sight as well as if they had received human donor corneas. In some respects, recovery of the eye was better than when compared to a human graft. "Nerve regeneration was faster in...
  • Reliance Life readies stem cell therapies

    07/01/2008 6:54:28 PM PDT · by Coleus · 144+ views
    live mint ^ | 07.01.08
    Mumbai: Seven years after its inception amid much fanfare, Reliance Life Sciences, or RLS, is finally rolling out stem cell-based therapies in India, beginning with a treatment that can restore or improve vision. “This is the first commercial stem cell treatment in ophthalmology in the country,” said K.V. Subramaniam, CEO and president, RLS, part of the Mukesh Ambani-led Reliance group. The company, which has invested around Rs1,000 crore in the business, has lined up other stem cell therapies for cardiac infarction, diabetic ulcer, and stable vitiligo or leukoderma (a skin disease), among others, to be offered in clinics in the...
  • New Artificial Cornea Could Restore Vision For Millions Worldwide

    05/19/2008 4:44:16 PM PDT · by Flavius · 6 replies · 84+ views
    science daily ^ | 5/19/08 | science daily
    ScienceDaily (May 19, 2008) — An improved artificial cornea, which could restore the vision of more than 10 million people worldwide who are blind due to diseased corneas, finally is moving toward reality, scientists in California conclude in a new analysis of research on the topic. Curtis Frank, Christopher Ta, David Myung, and Jennifer Cochran point out that disease or injury to the cornea -- the clear tissue covering the front of the eye -- is the second leading cause of blindness worldwide. Although treated in developed countries with transplants from donors, cornea transplants are unavailable in many parts of...
  • New Method Of Adult Stem Cell Growth Treats Cornea Disorders

    08/04/2007 8:45:44 PM PDT · by Coleus · 77+ views
    Science Daily ^ | 07.22.07
    A new method of adult stem cell growth, designed in the Area of Cellular Therapy of the University Clinic (University of Navarra), has demonstrated its efficacy for its capacity to grow cornea stem cells. So Ana Fernández Hortelano, ophthalmologist at the Hospital demonstrated applying the growth technique in treating diseases of the cornea, using stem cells, in 70 test animals (rabbits). The aim of the procedure was to regain the damaged epithelium and thus restore transparency to the cornea. In concrete, the thesis defended by doctor Fernández Hortelano at the Faculty of Medicine of the University of Navarra, proves the...
  • Bone Marrow Stem Cells May Cure Eye Disease

    05/10/2007 6:04:40 PM PDT · by Coleus · 2 replies · 177+ views
    Cincinnati - Adult bone marrow stem cells may help cure certain genetic eye diseases, according to UC researchers. Scientists have completed a study using mice which showed that bone marrow stem cells can switch roles and produce keratocan, a natural protein involved in the growth of the cornea—the transparent, outer layer of the eyeball. This ability of marrow cells to “differentiate” into keratocan-producing cells might provide a means for treating abnormal corneal cell growth in people. Winston Whei-Yang Kao, PhD, professor of ophthalmology, and Hongshan Liu, PhD, research scientist in the department of ophthalmology, will present their findings at the...
  • Adult Stem cell patch restores vision

    04/18/2007 4:39:08 PM PDT · by wagglebee · 17 replies · 2,166+ views
    LifeSiteNews ^ | 4/18/07 | LifeSiteNews
    MELBOURNE, April 18, 2007 ( - A man's vision has been restored by a corneal patch grown from adult stem cells by a team at the University of Melbourne's Centre for Eye Research Australia (CERA) and the Bernard O'Brien Institute of Microsurgery (BOBIM). The patch, which replicates the cornea, was cultivated from a single stem cell from a donor eye and was transplanted to the surface of the man's eyes. The research team was led by Dr Mark Daniell (CERA) and Dr Erik Thompson (BOBIM). The process, known as a limbal stem cell transplant, is thought to be the first...
  • Real-World Successes of Adult Stem Cell Treatments

    12/02/2006 7:28:38 PM PST · by Coleus · 3 replies · 682+ views
    FRC ^ | Mr. Bradley R. Hughes Jr.
    With increasing frequency, American citizens and others from around the globe are experiencing newfound freedom from disease, affliction, and infirmity. Individuals' lives are forever changed with the strengthened faith and renewed hope that arise from healed bodies and physical restoration. These seemingly miraculous cures are the result of adult stem cell treatments. Yet the debates in the popular media tend to ignore and obscure the medical breakthroughs made by adult stem cell research--success that has conspicuously eluded embryonic stem cell treatments.[1]  Adult stem cells (or, more accurately, tissue stem cells) are regenerative cells of the human body that possess the...
  • An eye on stem cells

    12/02/2006 1:17:31 PM PST · by Coleus · 2 replies · 396+ views
    The Hindu Magazine ^ | December 3, 2006 | DR. MOHAN RAJAN, DR. SUJATHA MOHAN, DR. SRINIVAS K. RAO, DR. S. RADHIKA
    Transplant of limbal stem cells offers hope to patients with corneal disorders. Photo: K. GopinathanUnique capacity: A part of the eye constantly renews itself.CAN you imagine a part of your eye that constantly renews itself for the whole of your life? Half the cells are replaced every two months under normal conditions. The cells replicate fast and move across the surface at an incredible speed of 60 to 80 mm per hour. These are the properties of the Corneal epithelium — the outermost layer, or "skin" of your cornea, composed of five to six layers of specialised cells that...
  • Now, vision possible with ADULT stem cells

    11/13/2006 9:28:13 PM PST · by Coleus · 18 replies · 590+ views
    Indian Express Newspapers ^ | 11.12.06 | Khushboo Sandhu
    “After every Diwali, a large number people are blinded while bursting fire crackers. There are others who suffer from blindness due to chemical burns. But there is a ray of hope for such patients,” said Dr Radhika Tandon, Additional Professor, Ophthalmology, All India Institute of Medical Sciences (AIIMS) at the national symposium on stem cells being held at Panjab University. “Standard corneal transplant does not work in cases where blindness is due to chemical burning. But stem cell transplant can prove to be effective,” she said, adding that stem cell transplants do not ensure a perfect vision, but the patient...
  • Stem cells used to restore vision

    05/02/2005 9:45:13 PM PDT · by Founding Father · 51 replies · 1,216+ views
    BBC News ^ | April 28, 2005
    Stem cells used to restore vision A hospital in West Sussex is pioneering the use of stem cells to restore the eyesight of patients. The trial, being carried out at the Queen Victoria Hospital, East Grinstead, has already helped 40 people see again. The surgery at the hospital has been developed over the past five years. Stem cells from the patient or a donor are used to redevelop the cornea, the transparent film at the front of the eye which lets in light. Opthalmic surgeon Sheraz Daya said: "Many people who've had injuries to their eyes, or even people born...