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Keyword: genetherapy

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  • Hearing quality restored with bionic ear technology used for gene therapy

    04/23/2014 1:36:03 PM PDT · by Red Badger · 14 replies
    medicalxpress.com ^ | 04-24-2014 | Provided by University of New South Wales
    Researchers at UNSW Australia have for the first time used electrical pulses delivered from a cochlear implant to deliver gene therapy, thereby successfully regrowing auditory nerves. The research also heralds a possible new way of treating a range of neurological disorders, including Parkinson's disease, and psychiatric conditions such as depression through this novel way of delivering gene therapy. The research is published today (Thursday 24 April) in the journal Science Translational Medicine. "People with cochlear implants do well with understanding speech, but their perception of pitch can be poor, so they often miss out on the joy of music," says...
  • Virus That Evolved in the Lab Delivers Gene Therapy into the Retina

    07/04/2013 6:38:53 PM PDT · by neverdem · 9 replies
    MIT Technology Review ^ | June 12, 2013 | Susan Young
    From millions of random mutations, scientists identify a virus that could make gene therapy for inherited retinal diseases safer and more effective.Special delivery: Eight weeks after the new virus was injected into the eye of a monkey, the activity of a fluorescent gene it delivered can be seen in spots across the retina. A new delivery mechanism shuttles gene therapy deep into the eye’s retina to repair damaged light-sensing cells without requiring a surgeon to put a needle through this delicate tissue. The approach could make it substantially easier to treat inherited forms of eye disease with this approach.Although still...
  • Gene therapy cures leukaemia in eight days

    03/27/2013 7:36:28 AM PDT · by Sir Napsalot · 2 replies
    NewScientist ^ | 3-26-2013 | Andy Coghlan
    WITHIN just eight days of starting a novel gene therapy, David Aponte's "incurable" leukaemia had vanished. For four other patients, the same happened within eight weeks, although one later died from a blood clot unrelated to the treatment, and another after relapsing. The cured trio, who were all previously diagnosed with usually fatal relapses of acute lymphoblastic leukaemia, have now been in remission for between 5 months and 2 years. Michel Sadelain of the Memorial Sloan-Kettering Cancer Center in New York, co-leader of the group that designed the trial, says that a second trial of 50 patients is being readied,...
  • HIV Vector Licks Leukemia

    12/10/2012 6:20:25 PM PST · by neverdem · 25 replies
    A gene therapy that uses infusions of patients’ own T cells genetically engineered to attack their tumors enjoyed its first successful and sustained demonstration of clinical-trial success in nine of 12 leukemia patients—two of whom have been in remission for more than two years. The therapy was pioneered by the University of Pennsylvania’s Perelman School of Medicine, whose researchers will present latest results from the study today at the American Society of Hematology (ASH)'s Annual Meeting and Exposition in Atlanta.According to Penn Perelman, the results pave the way for a potential paradigm shift in the treatment of these types of...
  • DNA-swap technology almost ready for fertility clinic

    10/25/2012 10:31:45 PM PDT · by neverdem · 8 replies
    NATURE NEWS ^ | 24 October 2012 | David Cyranoski
    Mitochondrial transfer could reduce the risk of childhood disease. Researchers say that technology to shuffle genetic material between unfertilized eggs is ready to make healthy babies. The technique could allow parents to minimize the risk of a range of diseases related to defects in the energy-producing cell organelles known as mitochondria. Mitochondrial defects affect an estimated 1 in 4,000 children, and can cause rare and often fatal diseases such as carnitine deficiency, which prevents the body from using fats for energy. They are also implicated in a wide range of more common diseases affecting children and adults, such as multiple...
  • Anti-cocaine vaccine described in Human Gene Therapy Journal

    06/19/2012 11:34:35 PM PDT · by neverdem · 12 replies
    Biology News Net ^ | June 18, 2012 | NA
    A single-dose vaccine capable of providing immunity against the effects of cocaine offers a novel and groundbreaking strategy for treating cocaine addiction is described in an article published Instant Online in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc. (http://www.liebertpub.com) The article is available free online at the Human Gene Therapy website (http://www.liebertpub.com/hum). "This is a very novel approach for addressing the huge medical problem of cocaine addiction," says James M. Wilson, MD, PhD, Editor-in-Chief, and Director of the Gene Therapy Program, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia. In...
  • Spell-Checked Stem Cells Show Promise Against Liver Disease

    10/13/2011 6:56:01 PM PDT · by neverdem · 14 replies
    ScienceNOW ^ | 12 October 2011 | Jocelyn Kaiser
    Enlarge Image Gene fix. Red cells in this slice of mouse liver are making a human protein called A1At. Credit: K. YUSA ET AL., NATURE (ADVANCED ONLINE EDITION) ©2011 MACMILLAN PUBLISHERS LTD. Researchers have taken a step toward showing how stem cells might one day be used to help patients born with a deadly liver disease. The researchers corrected a DNA spelling error in patient skin cells that had been converted into so-called induced pluripotent stem (iPS) cells, then coaxed the cells to form liver cells that seemed to function normally in mice. The approach is still a long...
  • Gene therapy and stem cells unite

    10/13/2011 6:30:34 PM PDT · by CutePuppy · 5 replies
    BBC ^ | October 12, 2011 | James Gallagher
    Two of the holy grails of medicine - stem cell technology and precision gene therapy - have been united for the first time in humans, say scientists.It means patients with a genetic disease could, one day, be treated with their own cells. A study in Nature corrected a mutation in stem cells made from a patient with a liver disease. Researchers said this was a "critical step" towards devising treatments, but safety tests were still needed. At the moment, stem cells created from a patient with a genetic illness cannot be used to cure the disease as those cells would...
  • Breakthrough in fight against fatal Ebola as new drug saves 100% of monkeys tested! (Praise God!)

    05/29/2010 4:21:54 PM PDT · by Niuhuru · 29 replies · 708+ views
    Daily Mail ^ | 10:57 PM on 29th May 2010 | Daily Mail Reporter
    A gene silencing approach can save monkeys from high doses of the most lethal strain of Ebola virus in what researchers call the most viable route yet to treating the deadly and frightening infection. They used small interfering RNAs or siRNAs, a new technology being developed by a number of companies, to hold the virus at bay for a week until the immune system could take over. Tests in four rhesus monkeys showed that seven daily injections cured 100 per cent of them. U.S. government researchers and a small Canadian biotech company, Tekmira Pharmaceuticals, worked together to develop the new...
  • Lego-like gene delivery system is child's play

    05/14/2010 10:03:45 AM PDT · by neverdem · 1 replies · 171+ views
    Highlights in Chemical Biology ^ | 12 May 2010 | Philippa Ross
    Functionalised gold nanoparticles make a more efficient and versatile delivery system for use in gene therapy and cancer treatment, claim Korean scientists. Gold nanoparticles are non-toxic and easily made and so provide an effective way to deliver therapeutic antisense DNA to disease causing genes. Antisense DNA that is covalently attached to the nanoparticles will bind to messenger RNA of a disease causing gene, preventing translation and therefore inactivating it. But previous systems could deliver only antisense DNA that was covalently cross-linked to gold nanoparticles, which needed to be individually synthesized for each gene of interest. Now, Kangseok Lee and Min Su Han at...
  • Gene Therapy Cures Canines of Inherited Form of Day Blindness, Penn Veterinary Researchers Say

    04/21/2010 10:00:39 AM PDT · by decimon · 4 replies · 139+ views
    Veterinary ophthalmology researchers from the University of Pennsylvania have used gene therapy to restore retinal cone function and day vision in two canine models of congenital achromatopsia, also called rod monochromacy or total color blindness. Achromatopsia is a rare autosomal recessive disorder with an estimated prevalence in human beings of about 1 in 30,000 to 50,000. It primarily affects the function of the cone photoreceptors in the retina and serves as a representative model for other more common inherited retinal disorders affecting cones. Cone function is essential for color vision, central visual acuity and most daily visual activities, which underlines...
  • Second Dose Of Gene Therapy For Inherited Blindness Proves Safe In Animal Study

    03/06/2010 10:41:26 PM PST · by neverdem · 4 replies · 271+ views
    Gene therapy for a severe inherited blindness, which produced dramatic improvements last year in 12 children and young adults who received the treatment in a clinical trial, has cleared another hurdle. The same research team that conducted the human trial now reports that a study in animals has shown that a second injection of genes into the opposite, previously untreated eye is safe and effective, with no signs of interference from unwanted immune reactions following the earlier injection. These new findings suggest that patients who benefit from gene therapy in one eye may experience similar benefits from treatment in the...
  • Longevity Tied to Genes That Preserve Tips of Chromosomes

    11/11/2009 4:03:13 PM PST · by decimon · 35 replies · 1,016+ views
    (BRONX, NY) — A team led by researchers at Albert Einstein College of Medicine of Yeshiva University has found a clear link between living to 100 and inheriting a hyperactive version of an enzyme that rebuilds telomeres — the tip ends of chromosomes. The findings appear in the latest issue of the Proceedings of the National Academy of Sciences. Telomeres play crucial roles in aging, cancer and other biological processes. Their importance was recognized last month, when three scientists were awarded the 2009 Nobel Prize in Physiology and Medicine for determining the structure of telomeres and discovering how they protect...
  • Brain disease treated by gene therapy - A treatment based on HIV finds first success in...

    11/08/2009 8:58:34 PM PST · by neverdem · 6 replies · 685+ views
    Nature News ^ | 5 November 2009 | Lizzie Buchen
    A treatment based on HIV finds first success in humans.Researchers have halted a fatal brain disease by delivering a therapeutic gene to the stem cells that mature into blood cells. The gene was transferred using a virus derived from HIV, a technique that researchers have pursued for more than a decade but has not been successful in humans until now. Together with his colleagues, paediatric neurologist Patrick Aubourg at INSERM — France's main biomedical research agency — and at the Saint-Vincent de Paul Hospital in Paris, developed the system to treat X-linked adrenoleukodystrophy (ALD), a neurodegenerative disease that affects young...
  • Gene therapy could remedy Parkinson's

    10/17/2009 10:31:51 PM PDT · by neverdem · 21 replies · 1,608+ views
    Nature News ^ | 14 October 2009 | Elie Dolgin
    Introducing three genes corrects motor defects in monkeys.A potential gene therapy for Parkinson's disease can correct motor deficits in monkeys without causing the jerky, involuntary movements that often accompany long-term treatments for the disease. The approach is undergoing preliminary testing in a handful of human patients, who have all shown promising signs of improvement.At present, the most common remedy for Parkinson's disease involves replacing dopamine — the neurotransmitter that is depleted in patients with the disease — by administering the dopamine precursor levodopa, or L-DOPA. Most patients initially regain near-normal motor control, but after several years on L-DOPA the majority...
  • Colour blindness corrected by gene therapy - Treated monkeys can now see in technicolour.

    09/17/2009 2:01:52 PM PDT · by neverdem · 15 replies · 747+ views
    Nature News ^ | 16 September 2009 | Elie Dolgin
    Dalton, a squirrel monkey treated with gene therapy, enjoys his new colour sense.Neitz Laboratory Researchers have used gene therapy to restore colour vision in two adult monkeys that have been unable to distinguish between red and green hues since birth — raising the hope of curing colour blindness and other visual disorders in humans."This is a truly amazing study," says András Komáromy, a vision researcher and veterinary ophthalmologist at the University of Pennsylvania in Philadelphia, who was not involved in the research. "If we can target gene expression specifically to cones [in humans] then this has a tremendous implication."About 1...
  • Embryonic-like Cells Advance Toward Disease Treatment

    06/02/2009 9:24:12 PM PDT · by neverdem · 8 replies · 576+ views
    ScienceNOW Daily News ^ | 1 June 2009 | Constance Holden
    Enlarge ImageOn track. Colonies of genetically corrected cells taken from Fanconi anemia patients show red and yellow, markers associated with pluripotency. Credit: Juan Carlos Izpisúa Belmonte Two papers published this week appear to bring closer the day when embryonic-like stem cells can be used to treat human diseases. One study describes what scientists say is the safest method yet to produce these cells. The other reports success in using the cells to begin correcting a rare genetic disorder known as Fanconi anemia. Induced pluripotent stem (iPS) cells were first reported in 2006 by Shinya Yamanaka, a researcher at Kyoto...
  • Designer Antibodies Derail Monkey AIDS Virus

    05/21/2009 1:33:20 AM PDT · by neverdem · 2 replies · 496+ views
    ScienceNOW Daily News ^ | 18 May 2009 | Jon Cohen
    Enlarge ImageDesigner genes. Monkeys given a virus that holds the DNA for lab-made antibodies dodged SIV.Credit: Malcolm Linton Researchers are reporting that a new antiviral strategy powerfully protects monkeys from SIV, the simian cousin of HIV. The approach combines elements of vaccines and gene therapy, and experts say the development could eventually lead to a vaccinelike weapon against AIDS--a goal that has thus far proved elusive. Vaccines work by priming the "adaptive" immune system to recognize and attack a specific invader. But despite 2 decades of research, several potential AIDS vaccines have failed to teach the immune system to...
  • Stomaching diabetes

    06/20/2008 9:38:11 PM PDT · by neverdem · 21 replies · 217+ views
    Science News ^ | June 19th, 2008 | Patrick Barry
    A radical technique for treating diabetes could recruit cells in the gut to make insulin SAN DIEGO — If your pancreas fails you, go with your gut. Inserting a gene into gut cells in mice enabled those cells to take over the pancreas’s job, producing insulin after meals, according to unpublished research announced June 18 in San Diego at the Biotechnology Industry Organization International Convention. The work may offer a novel way to treat diabetes. "This is the first time that we've engineered a tissue that is not the pancreas to manufacture insulin" in animals, says researcher Anthony Cheung, a...
  • Gene Therapy Improves Sight of Four Patients

    04/30/2008 9:34:35 PM PDT · by neverdem · 2 replies · 100+ views
    Science</em>NOW Daily News ^ | 28 April 2008 | Jocelyn Kaiser
    Enlarge ImageSeeing the light.Steven Howarth, 18, a patient in a U.K. gene-therapy trial for blindness, says he is now more comfortable walking home at dusk.Credit: BBC In what eye researchers are hailing as a major advance, gene therapy has partially restored the sight of four young adults born with severe blindness. In two small studies, the patients' ability to sense light improved, and two can now read several lines of an eye chart. All are still legally blind, but the same treatment could potentially prevent this type of blindness in babies. The four patients have a disease called Leber...
  • Gene Therapy Did Not Kill Patient, Study Finds

    11/27/2007 10:29:45 PM PST · by neverdem · 4 replies · 145+ views
    ScienceNOW Daily News ^ | 26 November 2007 | Jocelyn Kaiser
    Closure? The death of Jolee Mohr, shown here with her family, was unrelated to the gene-therapy treatment she received, the study's sponsor says.Credit: Mohr Family/AP Images Federal regulators have given a green light to a gene-therapy arthritis trial that was halted last summer after a patient died. New tests indicate that the therapy played no role in the death. The decision comes as a relief to gene-therapy researchers who had worried about a potential new setback for their field. The trial conducted by Targeted Genetics Corp. was shut down after the 24 July death of 36-year-old Jolee Mohr of Taylorville,...
  • National Center For Regenerative Medicine Researchers Find Methods For Treating Heart Attacks

    05/10/2007 6:48:21 PM PDT · by Coleus · 129+ views
    Heart attacks are the leading cause of death in both men and women, with over 450,000 deaths in the United States each year. Improving the treatments available to patients who have survived a heart attack is therefore imperative. Researchers from the National Center for Regenerative Medicine (NCRM) have identified two innovative and distinctly different methods to help treat patients recovering from a heart attack.  The first study showed that cell-based gene therapy to regenerate damaged cardiac muscle tissue and improve mechanical cardiac function was feasible using skeletal muscle stem cells modified to express a stem cell honing signal. The second...
  • Researchers first to map gene that regulates adult stem cell growth

    01/14/2007 7:52:26 PM PST · by Moonman62 · 2 replies · 302+ views
    Eurekalert ^ | 01/14/07 | University of Kentucky
    A new discovery in stem cell research may mean big things for cancer patients in the future. Gary Van Zant, Ph.D., and a research team at the University of Kentucky published their findings today in Nature Genetics, an international scientific journal. The researchers genetically mapped a stem cell gene and its protein product, Laxetin, and building on that effort, carried the investigation all the way through to the identification of the gene itself. This is the first time such a complete study on a stem cell gene has been carried out. This particular gene is important because it helps regulate...
  • Good News About the Blues: Scientists Discover Gene Therapy for Depression

    12/30/2006 3:30:05 PM PST · by NormsRevenge · 9 replies · 687+ views
    LiveScience.com on yahoo ^ | 12/30/06 | Robin Lloyd
    Scientists have discovered a new gene that makes mice happy, a finding that suggests another avenue of drugs for improving depression in humans. The research represents the first time that depression has been eliminated genetically in any organism, said Guy Debonnel, a psychiatrist and professor at McGill University. Debonnel and his colleagues achieved this effect by creating and breeding mice lacking a gene also found in humans that affects the transmission of the mood-modulating chemical serotinin. Mice without the gene, called TREK-1, acted as if they had been treated with anti-depressants for at least three weeks, he said. By removing...
  • Gene Therapy Reaches Muscles Throughout The Body And Reverses Muscular Dystrophy In Animal Model

    07/26/2004 11:00:17 AM PDT · by LibWhacker · 4 replies · 411+ views
    Bio.com ^ | 7/26/04
    07/26/04 -- Researchers have found a delivery method for gene therapy that reaches all the voluntary muscles of a mouse - including heart, diaphragm and limbs ? and reverses the process of muscle-wasting found in muscular dystrophy. "We have a clear 'proof of principle' that it is possible to deliver new genes body-wide to all the striated muscles of an adult animal. Finding a delivery method for the whole body has been a major obstacle limiting the development of gene therapy for the muscular dystrophies. Our new work identifies for the first time a method where a new dystrophin gene...
  • The Glimmering Promise of Gene Therapy [Parts I and II]

    11/28/2006 7:32:23 PM PST · by annie laurie · 8 replies · 576+ views
    MIT Technology Review ^ | November 14, 2006 | Horace Freeland Judson
    Its history is marred by failures, false hopes, and even death, but for a number of the most horrendous human diseases, gene therapy still holds the promise of a cure. Now, for the first time, there is reason to believe that it is actually working. Part I: By the late 1960s, molecular biologists had erected an overarching explanation of how genes work--their substance, their structure, their replication, their expression, their regulation or control. Or at least they had done so in outline, for prokaryotes, the simplest single-celled organisms (which include bacteria), and for the viruses, called bacteriophages, that prey upon...
  • FATHER OF GENE THERAPY GUILTY OF MOLESTING CHILD

    07/20/2006 7:45:16 AM PDT · by BerlinStrausbaugh · 29 replies · 1,308+ views
    Times (London) | 7/20/2006 | Sam Knight
    A top American scientist dubbed "the father of gene therapy" is facing two decades in prison after been convicted of molesting a colleague's daughter. William French Anderson, known to many in the competitive world of genetic research as "French", entered the annals of medicine in 1990 when he led a team that successfully implanted missing genes into the blood of a 3-year-old girl, enabling her recovery from a rare, hereditary disease. But yesterday the 69-year-old was found guilty of four counts of abuse towards the 10-year-old daughter of a research scientist who worked in his laboratory at the University of...
  • Jury in LA finds prominent geneticist guilty of molestation - William French Anderson

    07/19/2006 4:45:15 PM PDT · by NormsRevenge · 7 replies · 1,504+ views
    ap on Riverside Press Enterprise ^ | 7/19/06 | Linda Deutsch - ap
    LOS ANGELES A jury convicted world-renowned geneticist William French Anderson on Wednesday of molesting the daughter of a colleague. Anderson, 69, is widely credited as the "father of gene therapy," a promising but controversial experimental medical treatment that involves injecting healthy genes into sick patients. He was the first person to successfully treat a patient this way in 1990, launching the field. The white-haired Anderson sat stoically, staring straight ahead, his head held high. He showed no reaction as the verdicts were read. His wife, a renowned surgeon, sat in the front row of the spectator section behind him with...
  • Gene Therapy Injected Into The Brains' Of Mice With Huntington's Disease

    06/13/2006 5:40:47 PM PDT · by annie laurie · 2 replies · 162+ views
    Science Daily ^ | June 12, 2006 | Rush University Medical Center
    Researchers at Rush University Medical Center, Chicago, and Ceregene Inc., San Diego, have successfully used gene therapy to preserve motor function and stop the anatomic, cellular changes that occur in the brains of mice with Huntington’s disease (HD). This is the first study to demonstrate that, using this delivery method, symptom onset might be prevented in HD mice with this treatment. Results of the study were published in the Proceedings of the National Academy of Sciencesof the United States, June 13, 2006. “This could be an important step toward a disease modifying therapy,” says co-author Jeffrey H. Kordower, Ph.D., director...
  • Human Cloning: Sooner than you think?

    06/05/2006 3:54:23 PM PDT · by ritewingwarrior · 33 replies · 518+ views
    UK Telegraph ^ | June 5, 2006 | UK Telegraph
    Is the cloning of human babies' tissue an insult to god? Posted at: 22:01 A proposal to create babies that are both cloned and genetically altered to prevent serious hereditary disease has been outlined by the leader of the team that created Dolly the sheep, re-igniting the debate on the moral implications of cloning human beings. Ever since news that Dolly had been cloned from an adult cell made headlines around the world, Prof Ian Wilmut has repeatedly said he is "implacably opposed" to cloning a human being. But in his forthcoming book After Dolly, serialised in The Daily Telegraph,...
  • A cancer treatment you can't get here

    03/01/2006 11:35:48 AM PST · by voletti · 12 replies · 1,851+ views
    Business Week ^ | 3/1/06 | Bruce Einhorn
    China, with lower regulatory hurdles, is racing to a lead in gene therapy. Once a week, Hashmukh Patel, a 62-year-old retired semiconductor engineer from Silicon Valley, travels with his wife, Bena, from their Beijing hotel to Beijing-Haidian Hospital. They ride the crowded elevator to the ninth floor, enter a pleasant, sun-filled ward with private rooms, and Patel gets an injection that he hopes will save his life. Suffering from late-stage cancer of the esophagus, he has come to Beijing for a Chinese gene-therapy drug called Gendicine that's supposed to kill tumor cells. Patel tried just about everything before coming to...
  • Sickle Cell Disease Corrected In Human Models Using Stem Cell-based Gene Therapy

    12/27/2005 12:53:22 AM PST · by neverdem · 9 replies · 462+ views
    In a study to be published in the January 2006 issue of Nature Biotechnology, researchers led by a team of scientists at Memorial Sloan-Kettering Cancer Center have devised a novel strategy that uses stem cell-based gene therapy and RNA interference to genetically reverse sickle cell disease (SCD) in human cells. This research is the first to demonstrate a way to genetically correct this debilitating blood disease using RNA interference technology. To prevent the production of the abnormal hemoglobin that causes sickle cell disease, a viral vector was introduced in cell cultures of patients who have the disease. The vector carried...
  • Genes help immunity disease boy

    03/11/2005 10:15:24 AM PST · by Ernest_at_the_Beach · 30 replies · 464+ views
    BBC ^ | Thursday, 10 March, 2005, 23:06 GMT | staff
    Genes help immunity disease boy Mustaf now attends nursery Gene therapy has been successfully used to treat a four-year-old boy with no immune system, a team of British scientists has revealed.The boy, named only as Mustaf, had the rare life-threatening immune disorder known as ada-SCID. Doctors at Great Ormond Street Hospital used a harmless virus to deliver stem cells containing a corrective gene. It is the first successful treatment of ada-SCID in the UK. Five children have been treated in Milan, Italy. Children with ada-SCID have no working immune system. They are susceptible to even the most minor infection....
  • SoCal scientist accused of child molestation posts bond (Runner-up for Time Man of the Year, 1995)

    02/21/2005 7:08:46 PM PST · by NormsRevenge · 3 replies · 612+ views
    Bakersfield Californian ^ | 2/21/05 | AP - Los Angeles
    LOS ANGELES (AP) - A renowned University of Southern California gene therapy scientist accused of molesting two children over the past 20 years posted bond and was released from jail, authorities said Monday. William French Anderson, 68, was released shortly after 5 a.m. on bond, according to the county Sheriff's Department Web site. No other information was immediately released. Anderson is accused of molesting a girl he instructed in martial arts between 1997 and 2001. He has pleaded not guilty to a count of continuous sexual abuse of a child under age 14 and five counts of committing a lewd...
  • The Prophet of Immortality

    12/11/2004 8:31:49 AM PST · by Momaw Nadon · 24 replies · 1,831+ views
    Popular Science ^ | January 2005 Issue | Joseph Hooper
    Controversial theorist Aubrey de Grey insists that we are within reach of an engineered cure for aging. Are you prepared to live forever? On this glorious spring day in Cambridge, England, the heraldic flags are flying from the stone towers, and I feel like I could be in the 17th century—or, as I pop into the Eagle Pub to meet University of Cambridge longevity theorist Aubrey de Grey, the 1950s. It was in this pub, after all, that James Watson and Francis Crick met regularly for lunch while they were divining the structure of DNA and where, in February 1953,...
  • Gene therapy could build superathletes, scientist warns

    02/18/2004 10:28:50 PM PST · by endthematrix · 16 replies · 321+ views
    AP ^ | 2/16/2004 | Paul Recer, Associated Press
    <p>Gene injections in rats can double muscle strength and speed, researchers have found, raising concerns that the virtually undetectable technology could be used illegally to build super athletes. A University of Pennsylvania researcher seeking ways to treat illness said that studies in rats show that muscle mass, strength and endurance can be increased by injections of a gene-manipulated virus that goes to muscle tissue and causes a rapid growth of cells.</p>
  • Gene Therapy Study for Parkinson's Disease Begins

    08/19/2003 6:22:14 AM PDT · by Theodore R. · 202+ views
    Louisville, KY, Courier-Journal ^ | 08-19-03 | Ritter, Malcolm, AP
    Parkinson's Gene Therapy Study Begins By MALCOLM RITTER AP Science Writer NEW YORK (AP) -- Researchers slipped billions of copies of a gene into the brain of a Parkinson's disease patient Monday, marking the first attempt to test gene therapy in a person with that disease. The patient, 55-year-old Nathan Klein of Port Washington, N.Y., said he was "feeling fine" in a telephone interview a few hours after the surgery. Klein said the disease gave him a tremor in his right arm, and made him shuffle and have to catch himself sometimes from falling. Medicines offer some relief, he said,...
  • Aliens in America: The Strange Truth about Our Souls

    12/06/2002 7:22:03 AM PST · by Valin · 5 replies · 337+ views
    Does human history have a future? In his latest work, Aliens in America, political philosopher Peter Augustine Lawler argues that the advent of the new biotechnology—cloning, gene therapy, Prozac, Ritalin, and the like—means that we must consider anew the possibility that Americans are lving near the end of history, a time when full equality will be achieved through the elimination of al that is distinctively human about us: the ability to passionately love and hate, to strive nobly for truth and wisdom, to search for God. For the elimination of human distinctiveness is now being systematically pursued through the biochemical...
  • Who will be first to sport flourescent green hair?

    09/13/2002 2:57:13 PM PDT · by Pontiac · 26 replies · 357+ views
    Ohio.com ^ | Sep. 09, 2002 | KEITH MULVIHILL
    NEW YORK - Scientists have successfully inserted a foreign gene into the DNA of mice that was later incorporated into growing hair shafts. "This will allow us to search for genes that will give a cosmetic benefit as well as potential therapeutic benefits when inserted into the hair follicle," said the study's lead author Dr. Robert M. Hoffman of AntiCancer Inc., a San Diego, California-based biotechnology company. While the green fluorescent protein (GFP) gene, which comes from jellyfish, has no medical significance, the main goal was to determine if the researchers could make transgenic mouse hair. The mouse genome did...
  • BUBBLE BOY CURE

    06/27/2002 12:53:16 PM PDT · by NYer · 19 replies · 769+ views
    Associated Press Wire Feed ^ | June 27, 2002 | PAUL RECER
    WASHINGTON (AP) _ A single injection of genetically modified stem cells is all it took to cure two children of a complex form of an inherited immune system disorder often referred to as the ``bubble boy disease,'' researchers report. An experimental technique that altered genes in bone marrow stem cells restored the immune systems of the children, researchers from Italy and Israel said in a study appearing in the journal Science. The children were born with what experts said was the most complex form of severe combined immunodeficiency disorder, or SCID. ``Both children have been cured but ... both will...