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Keyword: hepatocytes

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  • More than 3,000 epigenetic switches control daily liver cycles

    12/14/2012 2:34:22 PM PST · by neverdem · 7 replies
    Biology News Net ^ | December 11, 2012 | NA
    Thousand of epigenetic switches in the liver control whether genes turn on or off in response to circadian cycles. The figure illustrates daily changes, every six hours, in five different...When it's dark, and we start to fall asleep, most of us think we're tired because our bodies need rest. Yet circadian rhythms affect our bodies not just on a global scale, but at the level of individual organs, and even genes. Now, scientists at the Salk Institute have determined the specific genetic switches that sync liver activity to the circadian cycle. Their finding gives further insight into the mechanisms behind...
  • Beyond liver transplants: Acutely damaged livers may be repaired via transplanted hepatocytes

    02/01/2010 10:52:12 AM PST · by decimon · 5 replies · 367+ views
    Tampa, Fla. (Feb. 01, 2010) – A research team from the National Taiwan University Hospital has evaluated the efficiency of transplanted hepatocyte (liver) cells in animal models severely damaged by two kinds of chemical toxicity to see whether and how transplanted hepatocytes were able to efficiently repopulate the toxin-induced, severely damaged livers. The results of this study are published in the current double issue of Cell Transplantation (18:10/11) and are freely available on-line at http://www.ingentaconnect.com/content/cog/ct/ . The study was carried out in the on-going effort to evaluate hepatocyte transplantation as an alternative to liver transplantation, not only because of the...