Keyword: interferon

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  • Genetic test fingers viral, bacterial infections: Method could help doctors treat children's fevers

    07/24/2013 12:29:45 AM PDT · by neverdem · 4 replies
    Science News ^ | July 16, 2013 | Tina Hesman Saey
    By differentiating between bacterial and viral fevers, a new test may help doctors decide whether to prescribe antibiotics. Fevers are a common symptom of many infectious diseases, but it can be difficult to tell whether viruses or bacteria are the cause. By measuring gene activity in the blood of 22 sick children, Gregory Storch, a pediatrician and infectious disease researcher at Washington University in St. Louis and colleagues were able to distinguish bacteria-sparked fevers from ones kindled by viruses. The activity of hundreds of genes changed as the children’s immune systems responded to the pathogens, but the team found that...
  • Newly identified natural protein blocks HIV, other deadly viruses

    02/12/2013 2:27:08 PM PST · by neverdem · 3 replies
    Biology News Net ^ | February 11, 2013 | NA
    A team of UCLA-led researchers has identified a protein with broad virus-fighting properties that potentially could be used as a weapon against deadly human pathogenic viruses such as HIV, Ebola, Rift Valley Fever, Nipah and others designated "priority pathogens" for national biosecurity purposes by the National Institute of Allergy and Infectious Disease. In a study published in the January issue of the journal Immunity, the researchers describe the novel antiviral property of the protein, cholesterol-25-hydroxylase (CH25H), an enzyme that converts cholesterol to an oxysterol called 25-hydroxycholesterol (25HC), which can permeate a cell's wall and block a virus from getting in....
  • Anti-cancer chicken eggs produced: genetically modified chicken's eggs with cancer fighting proteins

    01/14/2007 9:24:39 PM PST · by SirLinksalot · 7 replies · 1,282+ views
    BBC NEWS ^ | 01/14/2007
    Anti-cancer chicken eggs produced GM chickens could be a route to faster, cheaper drugs UK scientists have developed genetically modified chickens capable of laying eggs containing proteins needed to make cancer-fighting drugs. The breakthrough has been announced by the same research centre that created the cloned sheep, Dolly. The Roslin Institute, near Edinburgh, says it has produced five generations of birds that can produce useful levels of life-saving proteins in egg whites. The work could lead to a range of drugs that are cheaper and easier to make. Professor Harry Griffin, director of the institute, told the BBC: "One of...
  • Army testing finds drugs that may stop the SARS virus

    05/03/2003 2:57:47 PM PDT · by CathyRyan · 45 replies · 385+ views
    AP - nola.com ^ | 5/3/03 | DANIEL Q. HANEY
    <p>FORT DETRICK, Md. (AP) -- The first strong evidence that medicine will eventually defeat the SARS virus has come to light in recent days at the Army's biodefense labs, where the world's most intensive and systematic search for a cure is going on around the clock.</p>
  • At Fort Detrick, a race to treat SARS

    04/27/2003 5:01:52 AM PDT · by CathyRyan · 14 replies · 268+ views
    The Baltimore Sun ^ | April 27, 2003 | Staff
    <p>The only drug that has stopped the new coronavirus from replicating is interferon. But scientists fear that the dose required is too toxic to be safe.</p> <p>In all, Fort Detrick will be screening more than 800 drugs on the market, including 40 anti-virals used to treat AIDS, herpes, hepatitis and influenza. Finding an effective treatment among that group would be the best-case scenario because the drug could be used immediately.</p> <p>But none seems promising so far.</p> <p>Scientists are planning to test at least another 1,500 drugs that are under development in laboratories.</p>