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Keyword: mice

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  • New Mouse Model Explores Aggression in Females

    08/06/2014 12:58:21 PM PDT · by bunkerhill7 · 10 replies
    ALN Magazine ^ | Aug. 6, 2014 | Weizmann Institute of Science
    "Laboratory mice are one of the most common animal models used in biological and medical research...However, the artificial selection process also caused the mice to lose the very important trait of being able to survive in the wild. Besides these lost traits, the female lab mice developed the tendency to immediately mate with every male in their vicinity, including siblings and parents" '
  • Lab mice fear men but not women, and that's a big problem for science

    04/28/2014 11:12:50 AM PDT · by Scoutmaster · 33 replies
    TheVerge.com ^ | April 28, 2014 | Arielle Duhaime-Ross
    The history of science is one chock-full of mice and men. Historically, biological and medical research has largely depended on rodents, which provide scientists with everything from cells and organs to behavioral data. That's why a new study in which researchers found that mice actually fear men, but not women, has the potential to be so disruptive. It might mean that a number of researchers have published mouse studies in which their results reflect this male-induced stress effect — and they know nothing about it. "People have not paid attention to this in the entire history of scientific research of...
  • Puny mouse threatens to delay Colorado flood recovery

    02/06/2014 12:44:57 PM PST · by Olog-hai · 19 replies
    Daily Caller ^ | 12:33 PM 02/05/2014 | Greg Campbell
    Colorado Republican Rep. Cory Gardner is demanding an emergency waiver from the Endangered Species Act for a species of mouse that threatens to delay flood recovery in Colorado. The Preble’s Meadow Jumping Mouse is a threatened species under the ESA, meaning that any governmental action—such as flood recovery—must first consider potential impacts on the tiny animal’s habitat, even if that habitat was also destroyed in the flood that wiped out entire Colorado communities in September. On Monday, the Federal Emergency Management Agency sent a notice to Colorado officials that the presence of the mouse in the flood zone “may cause...
  • Scientists Develop An 'Elixir' That Reverses A Known Cause Of Aging

    12/22/2013 1:43:02 AM PST · by Windflier · 22 replies
    i09.com ^ | 20 December 2013 | George Dvorsky
    To date, we know of only two things that can reverse the effects of aging: caloric restriction and extensive exercise. But in a recent experiment, researchers applied a new compound to 2-year old mice, causing their muscles to regenerate to 6-month old levels. Incredibly, human trials may start next year. The new compound, nicotinamide mono nucleotide (NMN), worked surprisingly quickly when tested on mice. When administered early enough in the aging process, it was found to work within one week; the muscles of older 2-year old mice were "indistinguishable" from the younger 6-month old animals. It improved muscle wastage, restored...
  • Of Mice and Men: Who Let All the Vermin Into the White House?

    09/16/2013 8:32:52 AM PDT · by NOBO2012 · 7 replies
    Michelle Obama's Mirror ^ | 9-16-2013 | MOTUS
    Yes, it’s official: lying to the government is now legally sanctioned.   “I did not have sex with that woman; Ms. Lewinski.” Because, as we all know, everyone lies about sex. The president’s “reforms” aim to turn doctors into government agents, pressuring them financially to ask questions they consider inappropriate and unnecessary, and to violate their Hippocratic Oath to keep patients’ records confidential.(snip) Doctors and hospitals who don’t comply with the federal government’s electronic-health-records requirements forgo incentive payments now; starting in 2015, they’ll face financial penalties from Medicare and Medicaid. The Department of Health and Human Services has already paid...
  • Scientists Make Mice “Remember” Things That Didn’t Happen

    08/05/2013 10:23:42 AM PDT · by Red Badger · 26 replies
    MIT Technology Review ^ | 25 July 2013 | By Susan Young
    Researchers manipulate mouse neurons to create a false memory; the work could lead to a better understanding of how memories form. Remember this: The red neurons are the brain cells in the hippocampus of a mouse carrying a new memory of a particular place. Scientists have created a false memory in mice by manipulating neurons that bear the memory of a place. The work further demonstrates just how unreliable memory can be. It also lays new ground for understanding the cell behavior and circuitry that controls memory, and could one day help researchers discover new ways to treat mental illnesses...
  • A little radiation is good for mice

    06/03/2013 1:14:01 PM PDT · by Pontiac · 18 replies
    Science News ^ | Nov. 12, 2012 | Tina Hesman Saey
    X-rays may not heal broken bones, but low doses of ionizing radiation may spark other health benefits, a new study of mice suggests. Radiation in high doses has well-known harmful effects. Scientists had thought low doses would do less extensive damage but could add up to big problems later. But radiation acts differently at low doses, producing health benefits for mice with an unusual genetic makeup, Randy Jirtle of the University of Wisconsin–Madison and colleagues report online November 1 in the FASEB Journal. Antioxidant vitamins, such as vitamins C and E, erased those health gains. “What goes on at high...
  • Nineteenth Century Technique Turns Old Mouse Hearts Young

    05/15/2013 2:09:10 PM PDT · by neverdem · 16 replies
    ScienceNOW ^ | 9 May 2013 | Paul Gabrielsen
    Enlarge Image Young at heart. Cross-sections of mouse ventricles show the visible change in size when old hearts are immersed in young blood. Credit: Francesco Loffredo It's time to turn back the clock on an aging ticker. Drawing on an odd experimental technique invented more than a century ago but rarely done now, researchers have found that a blood-borne protein makes old mouse hearts appear young and healthy again. It's not clear yet whether humans would react the same way, but scientists are hopeful that this discovery may help treat one of the heart's most frustrating ailments. "This is probably...
  • Breakthrough Cancer-Killing Treatment Has No Side-Effects, Says MU Researcher

    04/04/2013 10:48:56 PM PDT · by Vince Ferrer · 18 replies
    University of Missouri ^ | April 3, 2013 | Timothy Wall
    COLUMBIA, Mo. – Cancer painfully ends more than 500,000 lives in the United States each year, according to the Centers for Disease Control and Prevention. The scientific crusade against cancer recently achieved a victory under the leadership of University of Missouri Curators’ Professor M. Frederick Hawthorne. Hawthorne’s team has developed a new form of radiation therapy that successfully put cancer into remission in mice. This innovative treatment produced none of the harmful side-effects of conventional chemo and radiation cancer therapies. Clinical trials in humans could begin soon after Hawthorne secures funding. “Since the 1930s, scientists have sought success with a...
  • Breakthrough nanoparticle halts multiple sclerosis

    11/21/2012 11:41:34 PM PST · by LibWhacker · 21 replies
    EurekAlert! ^ | 11/18/12 | Marla Paul
    New nanotechnology can be used for Type 1 diabetes, food allergies and asthma New nanoparticle tricks and resets immune system in mice with MSFirst MS approach that doesn't suppress immune systemClinical trial for MS patients shows why nanoparticle is best optionNanoparticle now being tested in Type 1 diabetes and asthma CHICAGO --- In a breakthrough for nanotechnology and multiple sclerosis, a biodegradable nanoparticle turns out to be the perfect vehicle to stealthily deliver an antigen that tricks the immune system into stopping its attack on myelin and halt a model of relapsing remitting multiple sclerosis (MS) in mice, according...
  • Hormone Combination Effective and Safe for Treating Obesity in Mice

    11/13/2012 10:07:02 PM PST · by neverdem · 25 replies
    ScienceDaily ^ | Nov. 13, 2012 | NA
    Scientists at Indiana University and international collaborators have found a way to link two hormones into a single molecule, producing a more effective therapy with fewer side effects for potential use as treatment for obesity and related medical conditions. The studies were carried out in the laboratories of Richard DiMarchi, the Standiford H. Cox Distinguished Professor of Chemistry and the Linda & Jack Gill Chair in Biomolecular Sciences in the IU Bloomington College of Arts and Sciences, and of Matthias Tschöp, professor of medicine and director of the Institute of Diabetes and Obesity, Helmholtz Center Munich, Germany. Results were published...
  • Mice That Eat Yogurt Have Larger Testicles (Probiotics may endow rodents with a "mouse swagger")

    04/27/2012 1:42:49 AM PDT · by rawhide · 24 replies
    Scientific American Magazine ^ | May 2, 2012 | Elie Dolgin
    Last sum­mer a team of researchers from the Massa­chusetts Institute of Technology set out to better understand the effects of yogurt on obesity. They were following up on the results of a long-term study from the Harvard School of Public Health that had suggested yogurt, more than any other food, helped to prevent age-related weight gain. The M.I.T. team, led by cancer biologist Susan Erdman and evolutionary geneticist Eric Alm, wanted to replicate the work in mice. The researchers took a group of 40 males and 40 females and either fed the animals a high-fat, low-fiber, low-nutrient diet meant to...
  • New synthetic molecules treat autoimmune disease in mice

    12/25/2011 11:25:41 AM PST · by decimon · 26 replies
    A team of Weizmann Institute scientists has turned the tables on an autoimmune disease. In such diseases, including Crohn's and rheumatoid arthritis, the immune system mistakenly attacks the body's tissues. But the scientists managed to trick the immune systems of mice into targeting one of the body's players in autoimmune processes, an enzyme known as MMP9. The results of their research appear today in Nature Medicine. Prof. Irit Sagi of the Biological Regulation Department and her research group have spent years looking for ways to home in on and block members of the matrix metalloproteinase (MMP) enzyme family. These proteins...
  • Milk thistle stops lung cancer in mice

    11/15/2011 1:03:55 PM PST · by decimon · 22 replies
    Colorado Cancer Blogs ^ | November 15, 2011 | Garth Sundem
    Tissue with wound-like conditions allows tumors to grow and spread. In mouse lung cancer cells, treatment with silibinin, a major component of milk thistle, removed the molecular billboards that signal these wound-like conditions and so stopped the spread of these lung cancers, according to a recent study published in the journal Molecular Carcinogenesis. Though the natural extract has been used for more than 2,000 years, mostly to treat disorders of the liver and gallbladder, this is one of the first carefully controlled and reported studies to find benefit. Here is how it works:Basically, in a cell there can be a...
  • Lipid Blocks Influenza Infection

    11/09/2011 12:07:12 PM PST · by decimon · 8 replies
    National Jewish Health ^ | November 9, 2011
    A natural lipid in the fluid lining the lungs inhibits influenza infections in both cell cultures and mouse models, according to researchers at National Jewish Health. These findings, combined with previous studies demonstrating effectiveness against respiratory syncytial virus, suggest that the molecule, known as POPG, may have broad antiviral activity. “Supplemental POPG could be an important, inexpensive and novel approach for the prevention and treatment of influenza and other respiratory virus infections,” said Dennis Voelker, PhD, Professor of Medicine, and senior author in the report, published online in the American journal of Respiratory Cell and Molecular Biology.
  • An Egg-Citing Recipe for Human Stem Cells

    10/13/2011 8:27:04 PM PDT · by neverdem · 4 replies
    ScienceNOW ^ | 5 October 2011 | Gretchen Vogel
    Enlarge Image Turn it on. A fused human egg cell and skin cell form an early embryo that turns on the skin cell's green fluorescent protein on day 4 of development and forms a blastocyst by day 6. Credit: Noggle et al., Nature 478 (6 October 2011) Researchers have found a new way to turn adult cells into embryonic stem (ES) cells: using human eggs, or oocytes. The feat comes after more than a decade of failed attempts, and it is still a work in progress. The resulting stem cells are not normal; they carry the genomes of both...
  • Spell-Checked Stem Cells Show Promise Against Liver Disease

    10/13/2011 6:56:01 PM PDT · by neverdem · 14 replies
    ScienceNOW ^ | 12 October 2011 | Jocelyn Kaiser
    Enlarge Image Gene fix. Red cells in this slice of mouse liver are making a human protein called A1At. Credit: K. YUSA ET AL., NATURE (ADVANCED ONLINE EDITION) ©2011 MACMILLAN PUBLISHERS LTD. Researchers have taken a step toward showing how stem cells might one day be used to help patients born with a deadly liver disease. The researchers corrected a DNA spelling error in patient skin cells that had been converted into so-called induced pluripotent stem (iPS) cells, then coaxed the cells to form liver cells that seemed to function normally in mice. The approach is still a long...
  • State: Mice Infest School Food Storage

    09/27/2011 2:24:51 PM PDT · by nickcarraway · 5 replies
    KRQE ^ | Thursday, 22 Sep 2011 | RUSSELL CONTRERAS
    State inspectors say a New Mexico school district's food warehouse is infested with rodent droppings, food hazards and improperly placed rat poison, and district officials refused to discard the food in question. The state Environment Department says officials cited last week five "high risk violations" at the food warehouse of Gallup-McKinley County Schools. State inspector Andrew Wilson wrote in a memo that the warehouse was littered with rodent droppings throughout, contained rat poison in a walk-in refrigerator and had cases of food with ice accumulation on top.
  • Mouse Stops US-bound SAS Flight in Stockholm

    08/23/2011 5:52:57 PM PDT · by nickcarraway · 6 replies
    The Local ^ | 16 Aug 11
    A wayward mouse forced the grounding of a US-bound SAS flight on Tuesday, leaving 250 travellers stranded at Stockholm’s Arlanda airport as crews tried in vain to capture the rogue rodent. Police return stolen bike after 15 years (23 Aug 11) McDonald's advert fakes 'Swedish' farmland (23 Aug 11) Sweden fears swimming Danish raccoon invasion (23 Aug 11) Shortly before the scheduled 10.30am take off of the Chicago-bound Airbus 330, a security guard spotted the mischievous mouse scurrying across the floor of the aircraft. “Unfortunately the mouse has not been found and caught, despite an extensive search onboard and numerous...
  • Apple Peel Makes Mice Mighty

    06/07/2011 12:12:36 PM PDT · by Pining_4_TX · 17 replies · 1+ views
    Medical News Today ^ | 06/07/11 | University of Iowa/Cell Metabolism
    For Popeye, spinach was the key to extra muscle. For the mice in a new University of Iowa study, it was apples, or more precisely a waxy substance called ursolic acid that's found in apple peel. The UI study, published in the June 8 issue of the journal Cell Metabolism, showed that ursolic acid reduced muscle atrophy (also known as muscle wasting) and promoted muscle growth in mice. It also reduced fat, blood sugar levels, cholesterol and triglycerides in the animals. The findings suggest that the compound may be useful for treating muscle wasting and possibly metabolic disorders such as...
  • MSNBC admits: Scientists *ARE* creating mice with completely human brains

    03/21/2011 7:03:46 AM PDT · by Moseley · 72 replies · 2+ views
    MSNBC ^ | April 29, 2005 | Associated Press
    Mice with human brains In January, an informal ethics committee at Stanford University endorsed a proposal to create mice with brains nearly completely made of human brain cells. Stem cell scientist Irving Weissman said his experiment could provide unparalleled insight into how the human brain develops and how degenerative brain diseases like Parkinson’s progress. Particularly worrisome to some scientists are the nightmare scenarios that could arise from the mixing of brain cells: What if a human mind somehow got trapped inside a sheep’s head? The “idea that human neuronal cells might participate in 'higher order' brain functions in a nonhuman...
  • Nanodiamonds Could Be a Cancer Patient's Best Friend

    03/15/2011 8:25:13 PM PDT · by neverdem · 8 replies · 1+ views
    ScienceNOW ^ | 9 March 2011 | Sara Reardon
    Enlarge Image Gem of a therapy? Clusters of nanodiamonds bearing chemotherapy drugs attack cancer cells. Credit: Science/AAAS If you give a nanodiamond to your fiancée, you can forget about the wedding. But a new study reports that these tiny flecks of carbon can shrink tumors in mice by delivering chemotherapy drugs to cancer cells. Lead author Dean Ho, a biomedical engineer at Northwestern University in Evanston, Illinois, says that one of the major challenges in chemotherapy is when tumor cells develop mechanisms to pump drugs right back out. But Ho reasoned that when the drug is bound to a...
  • Boosting protein garbage disposal in brain cells protects mice from Alzheimer's disease

    03/04/2011 10:56:12 AM PST · by decimon · 3 replies
    Georgetown University Medical Center ^ | March 4, 2011 | Unknown
    GUMC neuroscientists say their novel gene therapy shows that clearing toxic proteins inside brain cells prevents plaque formation outside neuronsWashington, D.C. – Gene therapy that boosts the ability of brain cells to gobble up toxic proteins prevents development of Alzheimer's disease in mice that are predestined to develop it, report researchers at Georgetown University Medical Center. They say the treatment – which is given just once - could potentially do the same in people at the beginning stages of the disease. The study, published online in Human Molecular Genetics, demonstrates that giving brain cells extra parkin genes promotes efficient and...
  • Bacteria in mouse gut affect development and behaviour

    02/02/2011 5:57:52 PM PST · by decimon · 7 replies · 1+ views
    BBC ^ | February 1, 2011 | Unknown
    The teeming trillions of bacteria in the digestive tracts of mice have been shown to affect the animals' brain development and behaviour.Mice bred in sterile environments without these "gut flora" were seen to be more adventurous and less anxious than mice with normal gut flora. The research adds weight to the idea that gut bacteria are a critical part of the overall development of mammals.
  • Harvard scientists reverse the ageing process in mice – now for humans

    11/29/2010 9:18:29 PM PST · by djf · 37 replies
    The Guardian ^ | Nov 28, 2010 | Ian Sample
    Harvard scientists were surprised that they saw a dramatic reversal, not just a slowing down, of the ageing in mice. Now they believe they might be able to regenerate human organs Scientists claim to be a step closer to reversing the ageing process after rejuvenating worn out organs in elderly mice. The experimental treatment developed by researchers at the Dana-Farber Cancer Institute, Harvard Medical School, turned weak and feeble old mice into healthy animals by regenerating their aged bodies. The surprise recovery of the animals has raised hopes among scientists that it may be possible to achieve a similar feat...
  • Today "Madam Hillary" Welcomes Questions From The Press,And Obama Runs Away Like A Mouse?

    11/29/2010 12:32:42 PM PST · by JohnThune2012 · 34 replies · 1+ views
    And Remember How The Lib's Proclaimed Obama As So Brilliant! So Intelligent!, Oh really? Then why can't he answer questions from the press on a regular basis?,it seems he will only take "Pre-Selected Questions" from a "Selected Press" AT HIS TIME & CONVENIENCE! After seeing Hillary take questions today,why don't we just put her in office and make Obama the "Secretary Of Teleprompters"?
  • Human brain has more switches than all computers on Earth

    11/18/2010 2:31:28 PM PST · by Ernest_at_the_Beach · 55 replies · 1+ views
    CNET ^ | November 17, 2010 12:03 PM PST | Elizabeth Armstrong Moore
    The human brain is truly awesome.A typical, healthy one houses some 200 billion nerve cells, which are connected to one another via hundreds of trillions of synapses. Each synapse functions like a microprocessor, and tens of thousands of them can connect a single neuron to other nerve cells. In the cerebral cortex alone, there are roughly 125 trillion synapses, which is about how many stars fill 1,500 Milky Way galaxies. This is a visual reconstruction from array-tomography data of synapses in the mouse somatosensory cortex, which is responsive to whisker stimulation.(Credit: Stephen Smith/Stanford) These synapses are, of course, so tiny...
  • Unexpected findings of lead exposure may lead to treating blindness

    10/25/2010 12:29:19 PM PDT · by decimon · 3 replies
    University of Houston ^ | October 25, 2010 | Unknown
    Research team at UH sees novel changes in retinal anatomy, results published in high-impact journalHOUSTON, Oct. 25, 2010 – Some unexpected effects of lead exposure that may one day help prevent and reverse blindness have been uncovered by a University of Houston (UH) professor and his team. Donald A. Fox, a professor of vision sciences in UH's College of Optometry (UHCO), described his team's findings in a paper titled "Low-Level Gestational Lead Exposure Increases Retinal Progenitor Cell Proliferation and Rod Photoreceptor and Bipolar Cell Neurogenesis in Mice," published recently online in Environmental Health Perspectives and soon to be published in...
  • A Cure For Diabetes: Medicine's Next Big Thing?

    10/11/2010 8:51:51 PM PDT · by Pining_4_TX · 37 replies · 1+ views
    ivanhoe.com ^ | 10/11/10 | Ivanhoe News
    Now, for the first time, researchers are using diabetes and "cure" in the same sentence. Doctor Donald Jump at Oregon State University eliminated diet-induced diabetes -- or type two diabetes -- in lab mice. "We saw that certain enzymes were being repressed by the high-fat diet," Donald Jump, Ph.D., department of nutrition and exercise sciences, said. The enzyme he's talking about is called fatty acid elongase-five. The more fat we eat, the less of the enzyme we produce. So, when researchers boosted the production of the enzyme in mice livers, they were cured of their diabetes in five days. "The...
  • Too much light at night at night may lead to obesity, study finds

    10/11/2010 2:58:19 PM PDT · by decimon · 54 replies · 1+ views
    Ohio State University ^ | October 11, 2010 | Unknown
    COLUMBUS, Ohio – Persistent exposure to light at night may lead to weight gain, even without changing physical activity or eating more food, according to new research in mice. Researchers found that mice exposed to a relatively dim light at night over eight weeks had a body mass gain that was about 50 percent more than other mice that lived in a standard light-dark cycle. "Although there were no differences in activity levels or daily consumption of food, the mice that lived with light at night were getting fatter than the others," said Laura Fonken, lead author of the study...
  • Using Poisoned Mice to Get Rid of Snakes!

    10/01/2010 11:48:39 PM PDT · by nickcarraway · 34 replies
    Sify News ^ | 2010-10-02
    US authorities are trying to get rid of venomous snakes in its territory of Guam in the Pacific Ocean by 'bombing' the island with poisoned mice. Using helicopters from its Naval Base in Guam, scientists from the US department of agriculture have dropped mice packed with acetaminophen into the jungles in a ploy to rid Guam of its population of brown tree snakes, Fox News reported citing military news outlet Stars and Stripes. Guam's snake problem began in the 1980s, when the creatures arrived on the island accidentally in military cargo. The drug has already undergone extensive testing, said Dan...
  • Mice With (Functioning) Human Brain Cells Created

    09/26/2010 6:21:34 AM PDT · by macquire · 11 replies
    National Geographic ^ | 12/14/2005 | Brian Handwerk
    "The difference [with the mice with human brain cells] is that, instead of splicing in bits of DNA, scientists are stuffing in cells," said McGee, the bioethicist. "Critics of this research would have you believe that to grow our cells in other creatures is repugnant and inhumane. Mice already grow human ears and are used in many experiments to grow colonies of other human cells," McGee said.
  • For all Christine 0'Donnell critics re "MICE" video...

    09/25/2010 5:32:49 PM PDT · by LibFreeUSA · 116 replies
    Scientific American ^ | Sep 25, 2010 | LibFreeUSA via John Rennie
    For all the Christine O'Donnell critics, bashers, AND SMEAR-MONGERS who are engaging in the 'Politics of Personal Destruction' by spreading innuendos and smears regarding a video where Christine O'Donnell makes comments about cross-breeding, I present the following: -"Irving Weissman of Stanford University and his colleagues pioneered these chimera experiments in 1988 when they created mice with fully human immune systems for the study of AIDS. Later, the Stanford group and StemCells, Inc., which Weissman co-founded, also transplanted human stem cells into the brains of newborn mice as preliminary models for neural research. And working with foetal sheep, Esmail Zanjani of...
  • Video: Christine O'Donnell ~ Mice with human brains!

    09/25/2010 5:08:08 PM PDT · by EveningStar · 155 replies
    YouTube ^ | September 20, 2010 | uploaded by cnewq5
    Christine O'Donnell believes scientists have created mice with fully functional human brains O'Donnell is Republican candidate for the US Senate (Delaware)
  • Automated Data Tattoos (now used for lab mice)

    09/15/2010 1:20:31 PM PDT · by fishtank · 16 replies
    http://somarkinnovations.com | 9-15-2010 | fishtank
    THIS IS FOR NEWS - NOT FOR ADVERTISEMENT purposes ...... ...... ...... "The Labstamp applies automated tail tattoos for mouse identification. The features are as follows: Reliable, legible identification * Human readable permanent tail tattoo * 46,656 unique alpha-numeric IDs * Green ink for pigmented animals Safe for the animal * Designed for mice 14 days and older * No anesthesia required Easy to use * 10 minutes of training to apply the ID * No training to read the ID Eliminates human variability * Automated machine to apply the ID * Consistent ID quality and readability "
  • Drug Can Stop Debilitating Condition of Diabetes in Mice

    09/14/2010 11:17:52 AM PDT · by Pining_4_TX · 11 replies
    infozine.com ^ | 09/10/10 | staffinfozine
    A drug developed at the University of Kansas has the potential to stop a debilitating condition of diabetes that often leads to pain in the extremities and even amputations, KU researchers have found.
  • Mouse Study May Help Explain Fish Oil's Benefits (reduces inflammation may prevent diabetes)

    09/03/2010 7:55:26 PM PDT · by SmartInsight · 32 replies
    Business Week ^ | Sept. 3, 2010 | Jenifer Goodwin
    Feeding obese mice omega-3 fatty acids reduced inflammation that can lead to diabetes, a new study finds. By studying fat tissue in the mice consuming fish oil, researchers found omega-3 fatty acids seem to act on a particular receptor on cells, GPR120, which, when activated, blocks inflammatory processes. Chronic inflammation can lead to insulin resistance, a precursor to diabetes. Therefore, "if we can fix the inflammation part, it's possible that we could prevent insulin resistance or even ameliorate diabetes," Talukdar explained.
  • What's lurking in your stadium food? (interactive map)

    07/26/2010 12:07:59 AM PDT · by rvoitier · 17 replies
    yum
  • Gene Knockout Makes Female Mice Masculine

    07/10/2010 5:55:13 PM PDT · by Upstate NY Guy · 31 replies
    Science Daily ^ | 7/9/10 | BMC Genetics
    The mammalian fucose mutarotase enzyme is known to be involved in incorporating the sugar fucose into protein. Female mice that lack the fucose mutarotase (FucM) gene refuse to let males mount them, and will attempt copulation with other female mice.. Chankyu Park worked with a team of researchers from the Korea Advanced Institute of Science and Technology and intriguingly gained some insight into the neurological basis of sexual preference. He said, "The FucM knockout mice displayed drastically reduced sexual receptivity, although pregnancy after forced mating attempts by normal sexually experienced males .
  • Rodent Scurries By as Obama Lauds Wall Street Vote

    05/20/2010 6:31:33 PM PDT · by Steelfish · 84 replies · 2,135+ views
    NYTimes ^ | May 20th 2010
    Rodent Scurries By as Obama Lauds Wall Street Vote May 20, 2010 WASHINGTON (AP) -- In the midst of his battle with the titans of Wall Street, President Barack Obama was nearly upstaged by a rodent. Obama had just begun a Rose Garden statement lauding the end of a Senate filibuster on his financial overhaul when some kind of rodent dashed out of the bushes to his right, just outside the Oval Office. As photographers snapped away in the sun-drenched garden, the critter scurried straight past the gray podium with the presidential seal and made a bee-line for another set...
  • How dark chocolate may guard against brain injury from stroke (Alas,...)

    05/06/2010 7:30:41 AM PDT · by decimon · 16 replies · 441+ views
    Johns Hopkins Medical Institutions ^ | May 5, 2010 | Unknown
    Johns Hopkins researchers discover pathway in mice for epicatechin's apparent protective effectResearchers at Johns Hopkins have discovered that a compound in dark chocolate may protect the brain after a stroke by increasing cellular signals already known to shield nerve cells from damage. Ninety minutes after feeding mice a single modest dose of epicatechin, a compound found naturally in dark chocolate, the scientists induced an ischemic stroke by essentially cutting off blood supply to the animals' brains. They found that the animals that had preventively ingested the epicatechin suffered significantly less brain damage than the ones that had not been given...
  • Gene flaw found in induced stem cells

    03/31/2010 9:24:28 PM PDT · by neverdem · 3 replies · 296+ views
    Nature News ^ | 31 March 2010 | Elie Dolgin
    Key difference between reprogrammed adult mouse cells and embryonic stem cells discovered.Stem-cell researchers have puzzled over why reprogrammed cells taken from adult tissues are often slower to divide and much less robust than their embryo-derived counterparts.Now, a team has discovered the key genetic difference between embryonic and adult-derived stem cells in mice. If confirmed in humans, the finding could help clinicians to select only the heartiest stem cells for therapeutic applications and disease modelling.Induced pluripotent stem (iPS) cells are created by reprogramming adult cells, and outwardly seem indistinguishable from embryonic stem (ES) cells. Both cell types are pluripotent — they...
  • Cat's away, mice play in Westminster Palace

    03/06/2010 10:48:53 AM PST · by JoeProBono · 16 replies · 640+ views
    baltimoresun. ^ | March 6, 2010
    London's Houses of Parliament, also known as Westminster Palace, has rodents, and the peers aren't exactly sure what to do about it. Ivan Anthony Moore-Brabazon, the House's administration chief, on Wednesday turned down suggestions to acquire cats. He says the felines could ingest mice poison or wander around the chamber and disrupt business. He favors the current tactic of using poison and mousetraps. Parliament staff have reported daily sightings of the rodents in the palace's restaurants and bars.
  • Male mice sing ultrasonic love songs

    03/05/2010 9:03:10 AM PST · by cajuncow · 15 replies · 294+ views
    msnbc ^ | 3-5-10 | By Jennifer Viegas
    Male mice drive females wild with ultrasonic love songs, suggests a new study. Since song quality varies, the mice world has its Justin Timberlake-like stars that impress females with their talents more than other willing, but not so able, males do.
  • Early life stress 'changes' genes

    11/09/2009 11:55:52 AM PST · by JoeProBono · 21 replies · 801+ views
    bbc ^ | 8 November 2009 | Victoria Gill
    A study in mice has hinted at the impact that early life trauma and stress can have on genes, and how they can result in behavioural problems. Scientists described the long-term effects of stress on baby mice in the journal Nature Neuroscience. Stressed mice produced hormones that "changed" their genes, affecting their behaviour throughout their lives. This work could provide clues to how stress and trauma in early life can lead to later problems...... The team found that mice that had been "abandoned" during their early lives were then less able to cope with stressful situations throughout their lives. The...
  • Could tale of slain Yale student Annie Le and 'person of interest' Ray Clark be about mice?

    09/16/2009 1:01:51 PM PDT · by pissant · 24 replies · 1,566+ views
    NY Daily News ^ | 9/16/09 | Mike Daly
    Along with the defensive wounds and the flunked lie detector test, investigators looking into the murder of Yale student Annie Le focused on a lab technician named Raymond Clark because of e-mails about the care of laboratory mice. In the e-mails, Clark is said to criticize Le for not adhering to the protocols for tending the mice kept in the basement as part of her lab's ongoing experiments. Le is said to have responded in a conciliatory tone, promising to keep to the protocols. Investigators wonder if Clark was not satisfied, if resentment suddenly flared to rage, if as crazy...
  • Mice Levitated in Lab

    09/09/2009 8:30:06 PM PDT · by Redcitizen · 8 replies · 954+ views
    Live Science ^ | Wed Sep 9, 11:51 am ET | Charles Q. Choi
    Scientists have now levitated mice using magnetic fields. Other researchers have made live frogs and grasshoppers float in mid-air before, but such research with mice, being closer biologically to humans, could help in studies to counteract bone loss due to reduced gravity over long spans of time, as might be expected in deep space missions or on the surfaces of other planets. Scientists working on behalf of NASA built a device to simulate variable levels of gravity. It consists of a superconducting magnet that generates a field powerful enough to levitate the water inside living animals, with a space inside...
  • Replacement teeth grown in mice

    08/04/2009 9:10:57 AM PDT · by decimon · 12 replies · 358+ views
    BBC ^ | Aug. 4, 2009 | Unknown
    The researchers used a fluorescent protein to track gene expression Researchers in Japan have successfully grown replacement teeth in mice, according to a report in PNAS journal.
  • Allergy meds slim down obese mice

    08/03/2009 8:38:35 PM PDT · by neverdem · 24 replies · 1,345+ views
    Science News ^ | July 27th, 2009 | Jenny Lauren Lee
    Animal study shows over-the-counter medications lower weight and treat type 2 diabetes Over-the-counter allergy medications turn obese, diabetic mice into healthy, normal-weight mice, researchers report. The new research focuses on mast cells, immune system players critical to the inflammatory response involved in allergies. The study appears along with three other independent studies in the July 26 online Nature Medicine that show a connection between type 2 diabetes and the immune system. “Certainly the study is very exciting,” says George King of Harvard University’s Joslin Diabetes Center in Boston, who was not involved in the research. “It’s the first type to...
  • Chinese Scientists Create Mice from Reprogrammed Skin Cells (bypasses need for embryonic cells)

    07/26/2009 7:10:01 PM PDT · by SeekAndFind · 5 replies · 241+ views
    Popular Science ^ | 7/26/2009 | Jeremu Hsu
    Chinese scientists have created live mice from mature skin cells that had reverted to an embryonic-like state. The scientific success could further defuse controversy over harvesting embryonic stem cells, but also raises new ethical issues about potentially making clones selected for specific traits. Reprogramming stem cells has become popular over recent years, because it avoids the cloning or embryo-destruction techniques which have traditionally been used by scientists to create embryonic stem-cell lines. The Chinese experiments now prove that reprogrammed adult stem cells can be made to create live offspring with normal bodies, at least in mice. Two Chinese teams injected...