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Associated Press The popular heartburn drugs Prilosec and Nexium don't appear to spur heart problems, say preliminary U.S. and Canadian probes announced Thursday. The Food and Drug Administration and its Canadian counterpart began reviewing the drugs, used by tens of millions of people, back in May, when manufacturer AstraZeneca provided them an early analysis of two small studies that suggested the possibility of a risk. Those studies compared treating the chronic heartburn known as gastroesophageal reflux disease, or GERD, with either of the two drugs or with surgery, and tracked patients for five to 14 years. The company's initial analysis...

People taking powerful antacid drugs called proton pump inhibitors face an increased risk of hip fracture, University of Pennsylvania researchers report. Common proton pump inhibitors include Aciphex, Nexium, Prevacid, Prilosec and Protonix; they are often prescribed for stomach conditions such as gastroesophageal reflux disease (GERD). The report is published in the Dec. 27 issue of the Journal of the American Medical Association. "If you take acid-suppression medications on a chronic basis and you are 50 or older, your hip fracture risk is even higher than usual," said study author Dr.Yu-Xiao Yang, an assistant professor of medicine and epidemiology. "In addition,...

THE CONSUMER Five popular heartburn drugs work in essentially the same way, but only one of them, Prilosec, is sold without a prescription. Does that mean it is not as effective as the others? No, doctors say, Prilosec works just as well as the prescription drugs for most people - but only if they can get their hands on it. The pills are in such short supply that many drugstores are asking customers to wait two weeks or more for fresh stocks. Some patients have tracked down the medicine by calling around to other stores or shopping on eBay. Others...