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Keyword: spinalcord

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  • Scientists find key protein for spinal cord repair

    11/03/2016 1:48:09 PM PDT · by Red Badger · 9 replies ^ | November 3, 2016 | Provided by: Duke University
    Adult zebrafish are capable of regenerating their spinal cords after a complete severing injury. This close-up of the cells involved reveals supporting glial cells (shown in red) are first to cross the gap between the severed ends. Neuronal cells (green) soon follow. Duke Regeneration Next researchers discovered that a protein in the glia called connective tissue growth factor, or CTGF, is crucial for this process. Credit: Mayssa Mokalled and Kenneth Poss, Duke University ============================================================================================================================ A freshwater zebrafish costs less than two bucks at the pet store, but it can do something priceless: Its spinal cord can heal completely after being...
  • Why I’ve Never Forgotten a Japanese Girl

    10/10/2016 11:59:13 AM PDT · by Sean_Anthony · 19 replies
    Canada Free Press ^ | 10/10/16 | Dr. Gifford Jones
    Even expensive MRIs, designed to detect even minute spinal cord changes, are at times unable to diagnose the cause of pain 58 years ago I made an unfortunate decision. I was in the wrong place at the wrong time with the wrong Japanese girl. But the problem was not what you’re thinking! Rather, I was in Tokyo, travelling with my wife and her parents. My father-in-law and I decided to experience a Japanese massage at the Imperial Hotel. During the event a petite masseuse suddenly struck the side of my head with a hard blow. I swear to High Heaven...
  • 'The Wind on My Legs': Stimulator Helps Paralyzed Men Move Again

    04/08/2014 11:42:25 AM PDT · by SeekAndFind · 2 replies
    NBC News ^ | 04/08/2014 | Maggie Fox
    ur men paralyzed after bad spinal cord injuries can all move their legs again, thanks to an electrical stimulator. Astonished researchers say they’d hoped for some result, but nothing like what they got. They think the stimulator is retraining the mens’ nerves to work with the brain again, despite the terrible damage. “This is wonderful news. Spinal cord injury need no longer be a lifelong sentence of paralysis,” said Dr. Roderic Pettigrew, director of the National Institute of Biomedical Imaging and Bioengineering, one of the National Institutes of Health. “It is just downright marvelous.” Rob Summers, now 28, was the...
  • FDA Approves Lyrica for Nerve Pain in Spinal Cord Injuries

    06/21/2012 1:57:33 PM PDT · by stillafreemind · 28 replies
    Yahoo ^ | June 21, 2012 | Sherry Tomfeld
    Pfizer Inc.'s drug Lyrica has gotten FDA approval for use in treating nerve pain due to spinal injuries. Lyrica, a pain drug, is Pfizer's second-biggest selling drug. It is expected that this new approval will help Lyrica pass Lipitor, the company's largest-selling drug for reducing cholesterol.
  • Milestone: First Adult Stem Cells Made That Work in the Brain

    01/21/2012 8:00:34 PM PST · by Coleus · 4 replies
    Lifenews ^ | 01.18.12 | Barbara Abney
    For the first time ever, stem cells from umbilical cords have been converted into other types of cells, which may eventually lead to new treatment options for spinal cord injuries and multiple sclerosis, among other nervous system diseases.  “This is the first time this has been done with non-embryonic stem cells,” says James Hickman, a University of Central Florida bioengineer and leader of the research group, whose accomplishment is described in the Jan. 18 issue of the journal ACS Chemical Neuroscience.“We’re very excited about where this could lead because it overcomes many of the obstacles present with embryonic stem cells.” ...
  • Spinal Cord Injury Patient Treated With Non-Matched Adult Stem Cells (now up and walking)

    12/10/2010 1:07:06 PM PST · by NYer · 31 replies
    Marketwire ^ | December 10, 2010
    SAN DIEGO, CA--(Marketwire - December 10, 2010) - Medistem Inc. (PINKSHEETS: MEDS) announced today peer-reviewed publication of its data on what is believed to be the first "combination therapy" adult stem cell protocol for spinal cord injury. The patient treated, who was 29 years old at the time, suffered a spinal cord injury resulting from an airplane crash on May 13th of 2008. He had no walking ability, intermittent pain and loss of sexual function. The patient was injected with a combination universal donor stem cell therapy in November of 2008, and January and July of 2009. A gradual improvement was observed subsequent to each...
  • In breakthrough, nerve connections are regenerated after spinal cord injury

    08/08/2010 10:23:36 AM PDT · by decimon · 48 replies · 1+ views
    University of California - Irvine ^ | August 8, 2010 | Unknown
    Researchers from UCI, UCSD and Harvard deleted a cell growth inhibitor called PTENIrvine, Calif. — Researchers for the first time have induced robust regeneration of nerve connections that control voluntary movement after spinal cord injury, showing the potential for new therapeutic approaches to paralysis and other motor function impairments. In a study on rodents, the UC Irvine, UC San Diego and Harvard University team achieved this breakthrough by turning back the developmental clock in a molecular pathway critical for the growth of corticospinal tract nerve connections. They did this by deleting an enzyme called PTEN (a phosphatase and tensin homolog),...
  • Adult Stem Cells: "I Will Walk Again", The Laura Dominguez Story

    12/15/2009 1:25:48 PM PST · by Coleus · 9 replies · 752+ views
    The Laura Dominguez StoryIf there was ever a woman on a mission, it’s Laura Dominguez.  Doctors once told her she’d never walk again.  And while she’s not ready to run a marathon, she’s already proving them wrong, with the best yet to come.   An oil spill on a San Antonio freeway is blamed for the car crash that sent Laura and her brother directly into a retaining wall one summer afternoon in 2001.  Laura was just 16 years old at the time and the crash left her completely paralyzed from the neck down.  Surgeons say she suffered what’s known as...
  • Spinal Cord Regeneration Enabled By Stabilizing, Improving Delivery Of Scar-degrading Enzyme

    11/10/2009 7:15:37 AM PST · by bogusname · 10 replies · 515+ views
    ScienceDaily ^ | Nov. 5, 2009 | ScienceDaily
    Researchers have developed an improved version of an enzyme that degrades the dense scar tissue that forms when the central nervous system is damaged. By digesting the tissue that blocks re-growth of damaged nerves, the improved enzyme -- and new system for delivering it -- could facilitate recovery from serious central nervous system injuries...
  • Regeneration Can Be Achieved After Chronic Spinal Cord Injury

    10/31/2009 9:34:11 PM PDT · by bogusname · 25 replies · 661+ views
    ScienceDaily ^ | Oct. 31, 2009 | ScienceDaily
    Scientists at the University of California, San Diego School of Medicine report that regeneration of central nervous system axons can be achieved in rats even when treatment delayed is more than a year after the original spinal cord injury...
  • Stem Cells Used To Reverse Paralysis In Animals

    01/31/2009 9:48:45 PM PST · by Coleus · 5 replies · 326+ views
    science daily ^ | 01.29.09
    A new study has found that transplantation of stem cells from the lining of the spinal cord, called ependymal stem cells, reverses paralysis associated with spinal cord injuries in laboratory tests. The findings show that the population of these cells after spinal cord injury was greater than comparable cells from healthy animal subjects. The results open a new window on spinal cord regenerative strategies. The transplanted cells were found to proliferate after spinal cord injury and were recruited by the specific injured area. When these cells were transplanted into animals with spinal cord injury, they regenerated ten times faster while...
  • Study: (ADULT) Stem Cells Reverse Paralysis in Rats

    01/29/2009 5:19:43 PM PST · by presidio9 · 24 replies · 658+ views
    LiveScience ^ | 01/29/09
    Transplanted adult stem cells have been found to reverse paralysis associated with spinal cord injuries in lab rats, a new study finds. The study, headed up by Miodrag Stojkovic, deputy director and head of the Cellular Reprogramming Laboratory at Centro de Investigacion Principe Felipe in Spain, involved transplanting so-called progenitor stem cells from the lining of rats' spinal cords into rodents with serious spinal cord injuries. The rats recovered significant motor activity one week after injury, Stojkovic and his co-authors wrote in the Jan. 27 early online edition of the journal Stem Cells. Spinal cord injury, for which no therapy...
  • Transplanted fat cells restore function after spinal cord injury

    12/11/2008 9:46:13 PM PST · by neverdem · 16 replies · 750+ views ^ | December 10, 2008 | NA
    A study published in the current issue of CELL TRANSPLANTATION (Vol.17, No. 8) suggests that mature adipocytes - fat cells - could become a source for cell replacement therapy to treat central nervous system disorders. According to the study's lead researcher, Dr. Yuki Ohta of the Institute of Medical Science, St. Mariana University School of Medicine, Kawasaki, Japan, adipose-derived stem/stromal cells have in the past been shown to differentiate into neuronal cells in an in vitro setting. In their study, for the first time fat cells have been shown to successfully differentiate into neuronal cells in in vivo tests. The...
  • To Russia, with hope of a miracle cure (adult stem cells for spinal cord injuries)

    11/19/2008 9:02:18 PM PST · by Coleus · 2 replies · 382+ views
    chicago ^ | 10.27.08 | Alex Rodriguez
    Every three months, David Martin, a quadriplegic, returns to a small clinic here in the Russian capital for therapy he cannot legally get back home in Kalamazoo, Mich.: injections of stem cells taken from his own body, at a cost of $12,000 per visit. Martin's American doctors have tried to dissuade him from believing that any improvement in his condition could be the byproduct of stem cell treatments, a therapy not yet approved in the U.S. No scientific evidence has ever shown that such treatments can repair human spinal cord injuries, experts say. Yet Martin notices glints of progress—a twinge...
  • Adult Stem Cells Help Repair Man's Back

    06/30/2008 10:04:48 PM PDT · by Coleus · 1 replies · 121+ views
    Citizen Link ^ | 06.09.08
    A spinal surgeon in Aurora, Colo., recently performed what's being called the first disc surgery in the United States using adult stem cells to help repair a man's injured lower back. "Stem cells have shown great promise over the past three years for treating back pain," Dr. Jeffrey Kleiner said. "In combination with the diskectomy, we hope to offer patients long-term relief from their back pain and to decrease their risk of needing additional surgeries." Adult stem cells have been injected into patients' backs and joints to promote tissue growth, but this is the first time stem cells have been...
  • Spine Surgeons at Pine Creek Medical Center Take the Lead in Utilizing Stem Cell Technologies

    06/30/2008 9:59:19 PM PDT · by Coleus · 1 replies · 102+ views
    street insider ^ | 06.10.08
    Spine surgeons at Pine Creek Medical Center in Dallas have established themselves as the leaders of a cutting-edge surgical procedure that utilizes a patient's own adult stem cells to regenerate tissue.   Doctors Douglas Won, Michael Rimlawi, and Francisco J. Battle, all spine surgeons, have extensive experience in harvesting adult stem cells during routine spinal procedures and delivering those cells back to their patients to aid in the treatment of severe back pain.  According to the World Research Group, disorders of the spine are one of the largest public health problems in the U.S. and as the population ages, incidents of...
  • Bend man travels to Mexico for stem cell cure

    06/29/2008 3:26:41 PM PDT · by Coleus · 3 replies · 106+ views
    KTVZ.COM ^ | 06.17.08 | Victoria Adelus
    For more than thirty years, Steve Foster has been living his life partially paralyzed, but he hopes a recent trip to Mexico is going to change that. "I want this...bad," said Foster, an adult stem cell patient. Foster traveled south to undergo the adult stem cell transplant procedure, in an effort to gain back what he once had. "I'm tired of this life, and the way it is now," he said. Julie Hood, a human biology assistant professor at Central Oregon Community College, says although the treatment isn't performed in the U.S., it has been performed successfully in other countries....
  • China Offers Unproven Medical Treatments

    01/05/2008 12:12:07 PM PST · by JACKRUSSELL · 5 replies · 115+ views
    The Associated Press / Google News ^ | January 5, 2007 | By Christopher Bodeen and Alan Scher Zagier
    (BEIJING) — They're paralyzed from diving accidents and car crashes, disabled by Parkinson's, or blind. With few options available at home in America, they search the Internet for experimental treatments — and often land on Web sites promoting stem cell treatments in China. They mortgage their houses and their hometowns hold fundraisers as they scrape together the tens of thousands of dollars needed for travel and the hope for a miracle cure. A number of these medical tourists claim some success when they return home: Jim Savage, a Houston man with paralysis from a spinal cord injury, says he can...
  • Sacramento man with a spinal injury looks to stem cells harvested from bone marrow to finally end

    12/09/2007 7:41:49 PM PST · by Coleus · 2 replies · 63+ views
    The Sacramento Bee ^ | December 8, 2007 | Dorsey Griffith
    Sacramento man with a spinal injury looks to stem cells harvested from bone marrow to finally end his crippling pain   Dr. Pasquale Montesano, operating Thursday at Sutter Memorial Hospital, shapes a piece of bone that he will fill with adult stem cells harvested from donor cadavers, then place into the spine of Perry Anderson. The hope is that the surgery will help Anderson finally heal from earlier spinal surgery. Bryan Patrick / See additional images They are not from human embryos, but the stem cells being packed into Perry Anderson's spine may help him heal from a surgery...
  • BREAKING - Australia Supreme Court just ordered removal of life support against family pleas

    12/19/2007 5:00:27 AM PST · by paulsy · 162 replies · 948+ views
    Australian news ^ | 12/19/07 | paularish1
    "Paulo Melo, 29, has been in a coma at the Royal Darwin Hospital for two weeks, after severing his spinal cord in a car crash." - read more below: doctor requested, family objected, court granted