Keyword: statins

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  • Statins: Heart disease drug speeds up ageing process, warns new research

    09/26/2015 6:30:32 PM PDT · by Swordmaker · 125 replies
    Sunday Express (UK) ^ | Sunday, Sept 27, 2015 | By LUCY JOHNSTON
    Fears are growing over the side effects of cholesterol-lowering pillsScientists have found the heart disease drug badly affects our stem cells, the internal medical system which repairs damage to our bodies and protects us from muscle and joint pain as well as memory loss. Last night experts warned patients to “think very carefully” before taking statins as a preventative medicine. A GP expert in the field said: “They just make many patients feel years older. Side effects mimic the ageing process.” The new research by scientists at Tulane University in New Orleans has reignited the debate about statin side effects which many doctors...
  • Statins: Still Overhyped After All These Years

    06/17/2015 9:00:12 AM PDT · by Oldpuppymax · 18 replies
    Coach is Right ^ | 6/17/15 | Michael D. Shaw
    In a rather self-serving review article entitled A historical perspective on the discovery of statins, Japanese biochemist Akira Endo hits all the conventional and PC notes in his 10-page (including references) trip down memory lane. From the get-go, in the abstract itself he tells us that Cholesterol is essential for the functioning of all human organs, but it is nevertheless the cause of coronary heart disease. Building on that knowledge, scientists and the pharmaceutical industry have successfully developed a remarkably effective class of drugsthe statinsthat lower cholesterol levels in blood and reduce the frequency of heart attacks. We would expect...
  • A $29-billion-dollar-a-year industry

    08/11/2014 12:15:33 PM PDT · by Sean_Anthony · 13 replies
    Canada Free Press ^ | 08/11/14 | Patrick D Hahn
    Part 1: My Spirit is Broken: Will the New Statin Guidelines Do More Harm Than Good? You use them or you die. This is what a doctor told Sulette Brown, a psychotherapist from Oklahoma, when she balked at taking statins, after shed been rushed to the emergency room for a heart attack. Since that night, her life has changed in ways she could not have imagined.
  • A cup of Earl Grey 'as good as statins' at fighting heart disease, study finds

    03/31/2014 9:04:27 AM PDT · by Nachum · 79 replies
    Telegraph ^ | 3/30/14 | Alice Philipson
    Drinking Earl Grey tea could help guard against heart disease, it has emerged, after a study found that bergamot extract - a key ingredient in the hot drink - is just as effective as statins at controlling cholesterol. Scientists believe bergamot, a fragrant Mediterranean citrus fruit which gives Earl Grey tea its distinctive flavour, can significantly lower cholesterol. They say it contains enzymes known as HMGF (hydroxy methyl glutaryl flavonones) which can attack proteins in the body known to cause heart disease. The study found bergamot could even be as effective as statins, used to control cholesterol but which can...
  • U.S. doctors urge wider use of cholesterol drugs

    11/13/2013 4:48:31 PM PST · by Tolerance Sucks Rocks · 58 replies
    The Washington Times ^ | November 13, 2013 | Marilynn Marchione - Associated Press
    For decades, if you asked your doctor what your odds were of suffering a heart attack, the answer would turn on a number: your cholesterol level. Now the nations first new heart disease prevention guidelines in a decade take a very different approach, focusing more broadly on risk and moving away from specific targets for cholesterol. The guidance offers doctors a new formula for estimating risk that includes age, gender, race and factors such as whether someone smokes.
  • Will doctors embrace new statin and heart attack prevention guidelines?

    11/13/2013 9:16:32 AM PST · by Armen Hareyan · 21 replies
    EmaxHealth ^ | 2013-11-12 | Kathleen Blanchard
    For years doctors have been focused on specific cholesterol numbers to help patients prevent initial and recurrent heart attack. New guidelines mean only those at high risk will be recommended to take the drugs. So how will doctors decide who is at high risk? More importantly what are physicians already saying about changes? Dr. Neil Stone of Northwestern University chaired the committee that wrote the new guidelines, which was a collaborative effort between the American Heart Association and the American College of Cardiology. No more statins to control cholesterol numbers say expertsInstead of looking at cholesterol numbers Stone said physicians...
  • Cholesterol limits lose their lustre

    03/02/2013 10:24:14 PM PST · by neverdem · 71 replies
    Nature News ^ | 26 February 2013 | Heidi Ledford
    Revised guidelines for heart health are set to move away from target-based approach. Soon after Joseph Francis learned that his levels of bad LDL cholesterol sat at twice the norm, he discovered the shortcomings of cholesterol-lowering drugs and of the clinical advice guiding their use. Francis, the director of clinical analysis and reporting at the Veterans Health Administration (VA) in Washington DC, started taking Lipitor (atorvastatin), a cholesterol-lowering statin and the best-selling drug in pharmaceutical history. His LDL plummeted, but still hovered just above a target mandated by clinical guidelines. Adding other medications had no effect, and upping the...
  • Diabetes Complication Responds to Topical Statin Drug

    11/30/2012 12:09:15 PM PST · by neverdem · 26 replies
    eMaxHealth ^ | November 29, 2012 | Deborah Mitchell
    People with diabetes face the possibility of a number of serious complications, including poor wound healing. Now a new study has found that application of a topical statin drug speeds up wound healing in mice with diabetes.Could a statin drug help diabetic wound healing? Diabetes has several characteristics that make recovering from wounds more challenging. For example, people with diabetes have a weakened immune system, which makes healing more problematic. Nerve damage (neuropathy), which is common in diabetes, can make individuals unable to feel the pain associated with a cut or blister until it becomes infected. Diabetes is also...
  • VANITY: Article by MD quoted by Rush today (low-fat diets, statin drugs all wrong)

    03/08/2012 1:28:48 PM PST · by Joe the Pimpernel · 41 replies
    I can't find the article that Rush was talking about. Does anybody have a link?
  • The Diabetes Dilemma for Statin Users

    03/06/2012 9:26:10 PM PST · by nickcarraway · 15 replies
    New York Times ^ | March 4, 2012 | Eric J. Topol
    Were overdosing on cholesterol-lowering statins, and the consequence could be a sharp increase in the incidence of Type 2 diabetes. This past week, the Food and Drug Administration raised questions about the side effects of these drugs and developed new labels for these medications that will now warn of the risk of diabetes and memory loss. The announcement said the risk was small and should not materially affect the use of these medications. The data are somewhat ambiguous for memory loss. But the magnitude of the problem for diabetes becomes much more apparent with careful examination of the data from...
  • Safety Alerts Cite Cholesterol Drugs Side Effects

    02/29/2012 11:44:07 AM PST · by neverdem · 36 replies · 1+ views
    NY Times ^ | February 28, 2012 | GARDINER HARRIS
    Federal health officials on Tuesday added new safety alerts to the prescribing information for statins, the cholesterol-reducing medications that are among the most widely prescribed drugs in the world, citing rare risks of memory loss, diabetes and muscle pain. It is the first time that the Food and Drug Administration has officially linked statin use with cognitive problems like forgetfulness and confusion, although some patients have reported such problems for years. Among the drugs affected are huge sellers like Lipitor, Zocor, Crestor and Vytorin. But federal officials and some medical experts said the new alerts should not scare people away...
  • Cholesterol-lowering drugs may reduce mortality for influenza patients

    12/16/2011 6:20:51 PM PST · by decimon · 7 replies
    Statins, traditionally known as cholesterol-lowering drugs, may reduce mortality among patients hospitalized with influenza, according to a new study released online by the Journal of Infectious Diseases. It is the first published observational study to evaluate the relationship between statin use and mortality in hospitalized patients with laboratory-confirmed influenza virus infection, according to Vanderbilt's William Schaffner, M.D., professor and chair of Preventive Medicine. "We may be able to combine statins with antiviral drugs to provide better treatment for patients seriously ill with influenza," said Schaffner, who co-authored the study led by Meredith Vandermeer, MPH, of the Oregon Public Health Division.
  • Cholesterol-lowering medication accelerates depletion of plaque in arteries

    12/13/2011 12:11:01 PM PST · by decimon · 33 replies
    New study reveals molecular mechanism promoting the breakdown of plaque by statinsIn a new study, NYU Langone Medical Center researchers have discovered how cholesterol-lowering drugs called statins promote the breakdown of plaque in the arteries... The findings support a large clinical study that recently showed patients taking high-doses of the cholesterol-lowering medications not only reduced their cholesterol levels but also reduced the amount of plaque in their arteries. However, until now researchers did not fully understand how statins could reduce atherosclerosis, the accumulation of fat and cholesterol that hardens into plaque in arteries, a major cause of mortality in Western...
  • Diet May Be Enough For Cholesterol Problems; Avoid Statin Side Effects

    08/24/2011 1:47:24 PM PDT · by TennesseeGirl · 53 replies
    Medical News Today ^ | 08/24/11 | Sy Kraft
    New research demonstrates that a diet based around plants, nuts and high-fiber grains lowered "bad" cholesterol more than a low-saturated-fat diet that was also vegetarian, meaning that one's dietary changes could be an alternative to statin medications for many people saving persons from some devastating side effects of the medications. After six months, people on the low-saturated-fat diet saw a drop in LDL cholesterol of 8 milligrams per deciliter (mg/dL), on average, according to findings in the Journal of the American Medical Association. (excerpted)
  • Diabetes Risk Rises as Statin Dose Increases [FReepers on Zocor, Lipitor, Crestor etc Please Read]

    06/24/2011 12:49:46 PM PDT · by freespirited · 38 replies
    Internal Medicine News ^ | 06/21/11 | Mary Ann Moon
    The risk of developing type 2 diabetes rises with increasing doses of statin therapy, according to the findings of a large meta-analysis in the June 22/29 issue of JAMA. "Our findings suggest that clinicians should be vigilant for the development of diabetes in patients receiving intensive statin therapy," said Dr. David Preiss of the BHF Glasgow (Scotland) Cardiovascular Research Centre at the University of Glasgow, and his associates. Several recent studies have suggested that statin therapy may raise the risk of diabetes, and some have indicated that the risk is higher at higher doses of the drugs. Dr. Preiss and...
  • Eggs Lower in Cholesterol than Thought: Study

    02/08/2011 1:39:12 PM PST · by Kaslin · 48 replies
    CBSNews ^ | February 8, 2011
    Gov't Research Also Shows Them Much Higher in Vitamin D; Dietitian: Credit Healthier Animal Feed, in Part(CBS) If you like eggs, this is good news: A new government study finds they're actually 14 percent lower in cholesterol and 64 percent higher in vitamin D than previously thought. Registered Dietitian Cynthia Sass stopped by the "The Early Show" Tuesday to explain what this may mean for your health. What caused this change in cholesterol and vitamin D levels? Sass, the author of "Cinch!: Conquer Cravings, Drop Pounds, and Lose Inches," told "Early Show" co-anchor Chris Wragge the saying "You are what...
  • Do Cholesterol Drugs Do Any Good?

    01/06/2011 6:16:40 PM PST · by Pining_4_TX · 100 replies
    Bloomberg Business Week ^ | 01/17/2008 | John Carey
    Yes, Wright saw, the drugs can be life-saving in patients who already have suffered heart attacks, somewhat reducing the chances of a recurrence that could lead to an early death. But Wright had a surprise when he looked at the data for the majority of patients, like Winn, who don't have heart disease. He found no benefit in people over the age of 65, no matter how much their cholesterol declines, and no benefit in women of any age. He did see a small reduction in the number of heart attacks for middle-aged men taking statins in clinical trials. But...
  • You like a statin with that?

    08/15/2010 9:52:48 AM PDT · by lakeprincess · 17 replies
    The Washington Times ^ | Aug. 15, 2010 | Jennifer Harper
    Make that a burger, fries and a side of Lipitor, please. It could happen. As a public service, British researchers are proposing that fast-food eateries dole out complimentary cholesterol-lowering statin drugs to offset the hazardous glories of their fatty cuisines.
  • Vitamin B3 beats Big Pharma's Zetia cholesterol drug

    03/30/2010 8:24:19 AM PDT · by Scythian · 104 replies · 2,324+ views
    (NaturalNews) The utter worthlessness of Big Pharma's cholesterol drugs was demonstrated recently by a study published in the New England Journal of Medicine which showed that niacin (a low-cost B vitamin) out-performs Merck's drug Zetia for preventing the build-up of arterial plaque, a symptom of cardiovascular disease. As the study reveals, Zetia failed miserably. Patients taking niacin showed a "significant shrinkage" in artery wall thickness, while those on Zetia showed no such improvement. At the same time, the rate of "cardiovascular events" in the niacin group was only one-fifth that in the Zetia group, demonstrating that niacin is far more...
  • A Common Cholesterol Drug Fights Cataracts, Too (statins)

    02/09/2010 4:46:53 PM PST · by decimon · 7 replies · 317+ views
    American Friends of Tel Aviv University ^ | February 9, 2010 | Unknown
    Broad new TAU study finds statins cut cataract risk in men almost in halfStatins, a class of drugs used to lower cholesterol levels, have been successfully fighting heart disease for years. A new study from Tel Aviv University has now found that the same drugs cut the risks of cataracts in men by almost 40%. "Doctors have known for some time that there is some sort of preventative effect that statins have against cataracts," says Dr. Gabriel Chodick of the Department of Epidemiology and Preventive Medicine at the Sackler Faculty of Medicine at Tel Aviv University, who led the study....
  • Distortion on information concerning heart disease risk factors and prevention

    11/01/2009 1:58:02 PM PST · by Pining_4_TX · 9 replies · 684+ views ^ | May 2, 2007 | Sandy Szwarc, BSN, RN, CCP
    A major medical paper on primary heart disease prevention admitted that cardiovascular disease risk factors have proven useless for predicting heart disease among our population and that reducing risks factors doesnt translate into reduced clinical disease or fewer premature deaths. But the solutions to this conundrum were the most unbelievable examples of ad-hoc reasoning.
  • Statin drugs may lower deaths from flu: study

    10/30/2009 3:50:15 PM PDT · by neverdem · 8 replies · 584+ views
    Reuters ^ | Oct 29, 2009 | Maggie Fox
    Patients taking statin drugs were almost 50 percent less likely to die from flu, researchers reported on Thursday in a study providing more evidence the cholesterol-lowering drugs help the body cope with infection. The findings are compelling enough to justify doing controlled studies in which some patients are given the drugs deliberately and some are not, said Meredith Vandermeer of the Oregon Public Health Division, who helped lead the study. "Our preliminary study shows these cholesterol-lowering medications called statins are associated with a decrease in mortality," Vandermeer told a news conference at a meeting of the Infectious Diseases Society of...
  • Cholesterol-Lowering Drugs Associated With 50% Lower Odds of Dying From Seasonal Flu

    10/30/2009 5:23:51 AM PDT · by dangerdoc · 20 replies · 779+ views
    Web MD ^ | 10/30/09 | Louise Chang, MD
    Oct. 29, 2009 (Philadelphia) -- Once again, the popular cholesterol-lowering statin drugs have been shown to be good for more than the heart: They may also lower your odds of dying of the flu. In a large study of people hospitalized with seasonal influenza, those who were taking statins were about 50% less likely to die than those who weren't taking the drugs. "Our preliminary research suggests there may be a role for statins in influenza treatment," says Meredith VanderMeer, MPH, of the Oregon Public Health Division. The statin drugs include Crestor, Lescol, Lipitor, Mevacor, Pravachol, and Zocor. The findings...
  • Differential effects of simvastatin and pravastatin... (Statins)

    10/28/2009 7:21:09 PM PDT · by TennesseeGirl · 48 replies · 2,058+ views
    Journal of Lipid Research ^ | 2009 | Weijiang Dong, Simona Vuletic, and John J. Albers
    Inhibitors of HMG-CoA reductase (statins) are widely used medications for reduction of cholesterol levels. Statin use significantly reduces risk of cardiovascular disease but has also been associated with lower risk of other diseases and conditions, including dementia. However, some reports suggest that statins also have detrimental effects on the brain......Our data suggest that simvastatin and pravastatin differentially affect expression of genes involved in neurodegeneration and that statin-dependent gene expression regulation is cell type specific (excerpted)
  • Statins cut heart failure mortality only in patients with ischemic disease

    09/22/2009 3:31:57 PM PDT · by TennesseeGirl · 10 replies · 1,063+ views
    Reuters ^ | 09/22/09 | Unknown
    NEW YORK (Reuters Health) - The impact of statin therapy on mortality in patients with decompensated heart failure is limited to those who have ischemic heart disease, say researchers from Israel. Dr. Roman Nevzorov and colleagues from Ben-Gurion University of the Negev in Beer-Sheva analyzed 1-year mortality rates in 887 patients hospitalized for acute decompensated heart failure. ..."The clinical question is whether a statin should be prescribed to every patient with heart failure," the investigators say. "Based on the recent randomized trials and results of our analysis the answer is probably no in the case of heart failure of non-ischemic...
  • Statins Linked to Lower Risk of Flu and COPD Deaths

    04/29/2009 5:00:59 PM PDT · by steve86 · 7 replies · 637+ views
    MedPage Today ^ | April 10, 2007 | Michael Smith
    Statins Linked to Lower Risk of Flu and COPD Deaths By Michael Smith, Senior Staff Writer, MedPage Today Published: April 10, 2007 Reviewed by Robert Jasmer, MD; Associate Clinical Professor of Medicine, University of California, San Francisco ALBUQUERQUE, N.M., April 10 -- The moderate use of statins is associated with a sharply reduced risk of death from chronic obstructive pulmonary disease, researchers here found. Action Points * Explain to interested patients that statins are prescribed to lower cholesterol, but evidence is mounting that they have other effects, including modulating the immune system. * Explain that this study found an association...
  • Statins found to lower clot risk (Clots in legs and lungs)

    03/31/2009 12:15:43 AM PDT · by neverdem · 18 replies · 985+ views
    Albany Times Union ^ | March 30, 2009 | MARILYNN MARCHIONE
    Associated Press Study says cholesterol drug taken by millions can reduce the danger ORLANDO, Fla. Statin drugs, taken by millions of Americans to lower cholesterol and prevent heart disease, also can cut the risk of developing dangerous blood clots that can lodge in the legs or lungs, a major study suggests. The results provide a new reason for many people with normal cholesterol to consider taking these medicines, sold as Crestor, Lipitor, Zocor and in generic form, doctors say...
  • Statins versus dementia

    07/28/2008 10:26:59 PM PDT · by neverdem · 4 replies · 95+ views
    Science News ^ | July 28th, 2008 | Nathan Seppa
    Drugs designed to fight cholesterol might also prevent Alzheimers and other dementia Older people taking statin drugs are less likely to develop dementia than their counterparts who dont take the pills, a study in the July 29 Neurology suggests. While the provocative finding offers hope that the cholesterol-reducing drugs might help against Alzheimers disease and other forms of dementia, scientists say this study is unlikely to be the last word on the topic. Indeed, it may just fuel an already lively debate over statins potential effect on dementia. Some research has hinted at benefits, while other studies, particularly in people...
  • U.S. study shows 150 percent jump in statin use

    06/27/2008 1:19:00 PM PDT · by TennesseeGirl · 56 replies · 291+ views
    Medlineplus ^ | June 25, 2008 | Reuters Health
    Reuters Health Wednesday, June 25, 2008 WASHINGTON (Reuters) - Use of cholesterol-lowering drugs called statins rose by 156 percent between 2000 and 2005, with spending jumping from $7.7 billion to $19.7 billion, the U.S. Agency for Healthcare Research and Quality reported on Wednesday. "The number of people purchasing statins nearly doubled when comparing 2000 and 2005, rising from 15.8 million people to 29.7 million people," the AHRQ report reads. The total number of outpatient prescriptions for statins rose from about 90 million in 2000 to nearly 174 million in 2005. Each individual spent $484 a year on average on statins...
  • Low level of 'bad cholesterol' increases death rate, researchers find

    03/29/2008 1:37:17 PM PDT · by Mount Athos · 111 replies · 2,937+ views
    mainichi japan ^ | March 29, 2008
    A health study by Japanese researchers has found that people with low levels of LDL cholesterol -- often referred to as "bad cholesterol" -- are more likely to die than those with higher levels. The finding comes as Japan prepares to introduce special health checkups from April, which list high LDL cholesterol as a factor in deciding whether a person has metabolic syndrome. It is likely the results of the survey will stir debate over the designation of LDL cholesterol as "bad." The study was led by Tokai University professor Yoichi Ogushi, who surveyed roughly 26,000 people who had at...
  • Bloodsuckers Vs. Lifesavers

    02/26/2008 8:55:02 PM PST · by Kaslin · 19 replies · 150+ views
    IBD ^ | February 26, 2008
    Enterprise: When a great American company offers a medicine that lengthens the lives of hundreds of millions of people, you might think politicians would say thank you. Instead they say: How dare you advertise it.Pfizer has just been pressured by Congress into dropping its main ad campaign for the cholesterol-lowering drug Lipitor, arguably the most popular medicine in the world and with very good reason. Lipitor can lower the deadly artery-clogging substance by as much as 60% and, when combined with regular exercise and a low-fat diet, prevents heart attacks and sudden deaths. Companies who do so much for so...
  • Cholesterol drug strips staph of color, virulence

    02/15/2008 12:35:11 PM PST · by Dysart · 25 replies · 167+ views
    Reuters via Yahoo ^ | 2-15-08 | Deena Beasley
    Potentially deadly staph bacteria may be easily defeated by the body's own immune system once stripped of their golden hue by a drug developed to lower cholesterol, according to new research.The findings offer a promising new direction in the fight against increasingly drug-resistant staph infections, according to the National Institutes of Health, which supported the research. An international team of researchers found that a "squalene synthase inhibitor," originally developed by Bristol Myers Squibb, blocks infections of Staphylococcus aureus, named for its "golden halo," in mice.Staph contains a carotenoid -- like beta carotene in carrots -- that acts like an antioxidant...
  • Great Drug, but Does It Prolong Life?

    01/28/2008 10:35:58 PM PST · by neverdem · 33 replies · 352+ views
    NY Times ^ | January 29, 2008 | TARA PARKER-POPE
    Statins are among the most prescribed drugs in the world, and there is no doubt that they work as advertised that they lower not only cholesterol but also the risk for heart attack. But in the fallout from the headline-making trial of Vytorin, a combination drug that was found to be no more effective than a simple statin in reducing arterial plaque, many people are asking a more fundamental question about statins in general: Do they prolong your life? And for many users, the surprising answer appears to be no. Some patients do receive significant benefits from statins, like...
  • Cholesterol-lowering drug linked to sleep disruptions

    11/07/2007 10:03:13 PM PST · by crazyshrink · 59 replies · 120+ views
    EurekAlert ^ | 7-Nov-2007 | Edwin K. Kwon, B.A.; Michael H. Criqui, M.D., M.P.H.; and Joel E. Dimsdale, M.D.
    American Heart Association meeting report ORLANDO, Nov. 7 A cholesterol-lowering drug appears to disrupt sleep patterns of some patients, researchers reported at the American Heart Associations Scientific Sessions 2007. The findings are significant because sleep problems can affect quality of life and may have adverse health consequences, such as promoting weight gain and insulin resistance, said Beatrice Golomb, M.D., lead author of the study and an associate professor of medicine and family and preventive medicine at the University of California at San Diego School of Medicine. In the largest study of its kind, researchers compared two types of cholesterol-lowering...
  • Statins reduce loss of function, keeping old lungs young - even in smokers

    10/12/2007 8:08:03 AM PDT · by crazyshrink · 35 replies · 860+ views
    Statins are known to be good for lowering cholesterol and maybe even fighting dementia, and now they have another reported benefit: they appear to slow decline in lung function in the elderly even in those who smoke. According to researchers in Boston, it may be statins anti-inflammatory and antioxidant properties that help achieve this effect. To determine whether smoking status modified that effect, the researchers also divided their subjects into four smoking groups: never-smokers, long-ago quitters, recent quitters and current smokers. Within each smoking group, those not taking statins were estimated to experience faster declines in FEV1 and FVC than...
  • Cherry Garcia and the End of Socialized Medicine

    10/10/2007 12:07:30 PM PDT · by 2ndDivisionVet · 42 replies · 2,001+ views
    City Journal ^ | Autumn 2007 | Peter W. Huber
    On June 19, 1987, Ben & Jerrys introduced Cherry Garcia, in honor of the man who played lead guitar for the Grateful Dead. The Food and Drug Administration struck back three months later, when it approved the first of a new family of statin drugs that curb cholesterol production in the human liver. A synthetic statin licensed a decade later would become the most lucrative drug in history. At its peak, Lipitor was streaming $14 billion a year into Pfizers coffers. Lets not blame the victim: we dont choose Cherry Garcia; it chooses us. Lipitor is a lifesaver for 600,000...
  • Cholesterol-lowering statins may help prevent Alzeimer's, too, study suggests

    09/04/2007 9:11:54 AM PDT · by vietvet67 · 21 replies · 708+ views
    IHT ^ | September 4, 2007 | Nicholas Bakalar
    Elderly people taking statins had fewer of the twisted nerve-cell fibers that are common in the brains of patients with Alzheimer's disease, researchers reported last week in a study based on brain autopsies. The significance of the finding remains unclear, but this is the first time the potential effects of the cholesterol-lowering statins on brain pathology have been assessed by autopsy. Epidemiological studies of statins and Alzheimer's have had mixed results. The researchers examined the brains of 110 men and women ages 65 to 79 who were enrolled in a larger study of dementia and had donated their brains for...
  • No Evidence That Widely Prescribed Statins Protect Against Prostate Cancer

    08/09/2007 7:39:00 PM PDT · by blam · 4 replies · 274+ views
    Science Daily ^ | 8-10-2007 | American Association Of Cancer Research
    Source: American Association for Cancer Research Date: August 10, 2007 No Evidence That Widely Prescribed Statins Protect Against Prostate Cancer Science Daily A large community-based study refutes previous findings that statins -- a top-selling drug class, worldwide -- might cut one's risk of developing prostate cancer by reducing production of the male hormones that fuel cancer growth. Researchers from the New England Research Institutes found that while men using statins did indeed have lower blood levels of androgens such as testosterone, it was more likely attributable to poor health rather than the use of statins. "The public health significance...
  • A Risk in Cholesterol Drugs Is Detected, but Is It Real?

    07/03/2007 3:00:09 PM PDT · by Dysart · 41 replies · 1,405+ views
    WSJ ^ | 7-3-07 | Avery Johnson
    As he examined data on a computer one day last fall, drug-safety reviewer Ralph Edwards saw something that concerned him: Of 172 people in his database who developed Lou Gehrig's disease or something similar while taking prescription medicines, 40 had been on statins, the huge-selling cholesterol drugs. Dr. Edwards, director of the World Health Organization's drug-monitoring center, has amassed about four million reports of medical problems experienced by people taking prescription drugs. His job is to sift through these so-called adverse events, looking for "signals" of potential side effects. The number of Lou Gehrig's cases associated with statins struck Dr....
  • The Deeper I Go Into It, The Fishier Statins Seem To Become

    03/31/2007 4:37:45 PM PDT · by blam · 142 replies · 4,129+ views
    The Telegraph (UK) ^ | 3-31-2007 | James LeFanu
    The deeper I go into it, the fishier statins seem to become, Sunday Telegraph Last Updated: 11:25pm BST 31/03/2007 Second opinion Statins again, whose mass prescription is turning out to be much more serious (and sinister) than I could have supposed. The response to my last two columns has been, almost literally, overwhelming, so why are doctors apparently so unaware of the devastating symptoms they can cause? The British Heart Foundation (whose chairman, Professor Peter Weissberg accused me last week of being "easily led" on this matter) claims that statins have "minimal side effects" compared to those taking controlled...
  • If You Want To Feel Younger, Forget Your Statins

    03/17/2007 6:01:45 PM PDT · by blam · 165 replies · 4,881+ views
    The Telegraph (UK) ^ | 3-17-2007 | James LeFanu
    If you want to feel younger, forget your statins By James LeFanu, Sunday Telegraph Last Updated: 11:20pm GMT 17/03/2007 A doctor accused of wittingly prescribing useless or possibly lethal drugs would vehemently - and understandably - deny it. This makes it rather difficult to oppose the prevailing medical consensus on statins - the cholesterol-lowering drugs prescribed to four million people in Britain at a cost of 1 billion a year. That's quite a sum. It could pay the salaries of 700,000 nurses or build two spanking new teaching hospitals. An even bigger sum is 15 billion. That is the profit...
  • Statins Defend Against Fungus-Caused Sepsis

    10/15/2006 6:26:50 PM PDT · by blam · 1 replies · 255+ views
    Science News ^ | 10-14-2006 | Nathan Seppa
    Statins defend against fungus-caused sepsis Nathan Seppa From San Francisco, at the Interscience Conference on Antimicrobial Agents and Chemotherapy When a blood infection causes an inflammatory reaction that attacks the entire circulatory system, the result is a condition called sepsis that's fatal about 40 percent of the time. A new study suggests that sepsis brought on by a fungal infection is less lethal in people taking cholesterol-lowering pills called statins than in those not getting the drugs. Physician Graeme Forrest of the University of Maryland Medical Center in Baltimore says that he noticed reports suggesting that statins improve the survival...
  • Common heart drugs might be bird flu weapon

    06/30/2006 10:59:34 AM PDT · by annie laurie · 10 replies · 603+ views ^ | June 21, 2006 | Reuters
    WASHINGTON - The worlds top-selling drugs, cholesterol-lowering statins, might provide a way to treat feared bird flu, according to a doctor and retired drug company executive who is trying to get the researchers to study the possibility. Antivirals that affect the influenza virus are in short supply, and it will be years before vaccine makers can ramp up capacity enough to immunize the worlds population against a pandemic flu. But what if there was a cheap and widely available drug that helped treat the flus worst symptoms and possibly save lives? Evidence suggests that statin drugs, designed to lower cholesterol,...
  • Statins may reduce risk of cataracts

    06/21/2006 12:25:49 AM PDT · by neverdem · 19 replies · 491+ views
    Seattle Post-Intelligencer ^ | June 20, 2006 | LINDSEY TANNER
    AP MEDICAL WRITER CHICAGO -- Statins, the cholesterol-lowering drugs taken by millions of Americans, might also reduce the risk of cataracts, a preliminary study suggests. Adults who took statins were found to be 45 percent less likely to develop the most common type of age-related cataracts. Other researchers warned that something other than statins might explain the results and that the study does not prove cause-and-effect. The results were a surprise because of earlier concerns that some cholesterol medication might increase the risk of cataracts, a common clouding-over of the lens of the eye that can lead to poor vision...
  • Natural substance lowers cholesterol better than statins

    02/14/2006 1:50:42 AM PST · by djf · 48 replies · 4,822+ views
    net ^ | Jan 2004 | Michael Janson
    Policosanol and Cholesterol Revisited Policosanol, a mixture of waxy alcohols derived from sugar cane, rice bran oil, or wheat germ oil, has remarkable benefits for atherosclerosis that go beyond lowering cholesterol. Doctors recommend statin drugs to lower cholesterol, often even for people with normal serum levels, noting that these drugs have other benefits in stabilizing plaque and protecting endothelial cells. A friend told me that she lowered her cholesterol from 224 to 178 by taking policosanol, but her doctor was concerned that she might not be getting all the benefits of statins (but of course she was also avoiding the...
  • Crestor May Pose Risk of Muscle Damage

    03/03/2005 12:48:37 AM PST · by neverdem · 12 replies · 675+ views
    The Washington Post ^ | March 3, 2005 | Marc Kaufman
    FDA Issues Warning on Use of Cholesterol Drug, Especially by Asians The popular new cholesterol-lowering drug Crestor may cause an increased risk of potentially life-threatening muscle damage, especially in people of Asian ancestry, the Food and Drug Administration said yesterday. In a formal advisory, the agency said the risk is small and was largely identified and understood when the drug was approved in 2003. But because of new post-market studies that underscored the concerns, the agency concluded that the public should be informed and that warnings on the product label should be strengthened. The advisory, and accompanying new instructions to...
  • FDA mulls availability of drug for cholesterol

    01/14/2005 12:10:21 AM PST · by neverdem · 7 replies · 479+ views
    The Washington Times ^ | January 14, 2005 | Tom Ramstack
    The Washington Times FDA mulls availability of drug for cholesterolBy Tom RamstackTHE WASHINGTON TIMESPublished January 14, 2005 A Food and Drug Administration advisory panel is scheduled to recommend today whether a drug aimed at treating high cholesterol should be sold from store shelves like common remedies for headaches, colds and allergies. Merck & Co. and Johnson & Johnson, in a joint venture, have asked the FDA to let them sell a low-dose version of cholesterol-lowering Mevacor directly to consumers. During the first day of a two-day hearing yesterday at a Bethesda, Md., hotel, FDA drug advisers questioned whether...
  • FDA Considers Over-the-Counter Sales for Cholesterol Drug

    01/13/2005 4:02:49 AM PST · by foolscap · 14 replies · 748+ views ^ | Jan 13, 2005 | Laura Meckler
    WASHINGTON (AP) - The government is considering whether a drug for a serious chronic condition - high cholesterol - should sit on drugstore shelves alongside medicines for headaches, allergies and athlete's foot. Supporters say making a low-dose cholesterol medicine available without a doctor's prescription would help get needed treatment to millions of Americans who are at risk of heart disease. "There's a huge treatment gap," said Jerry Hansen, vice president of marketing at Johnson & Johnson-Merck Consumer Pharmaceuticals Co., a joint venture that is asking the Food and Drug Administration for permission to sell a low-dose version of Mevacor over...
  • A Quandary in Good News

    01/07/2005 12:04:07 PM PST · by neverdem · 5 replies · 652+ views
    NY Times ^ | January 7, 2005 | GINA KOLATA
    Suppose there were an anti-inflammatory drug that sharply reduced the level of CRP, the protein that has proved to be as powerful an indicator of heart disease risk as high cholesterol. A doctor might well prescribe such a drug for a patient with high levels of the protein. After all, CRP is linked to inflammation, and high levels of it are linked to heart attacks. As it turns out, there are such drugs. But this may not be good news. The anti-inflammatory drugs that lower CRP levels are COX-2 inhibitors, the very drugs that were recently found to increase the...
  • Seeking a Fuller Picture of Statins

    07/20/2004 8:50:40 PM PDT · by neverdem · 44 replies · 4,938+ views
    NY Times ^ | July 20, 2004 | DAVID TULLER
    Among cardiologists, it has become a running joke: maybe the powerful drugs known as statins should be added to the water supply. Not only do statins greatly reduce cholesterol and lower mortality in people at risk for heart attacks, but some studies also suggest that they might help to prevent or treat a wide range of ailments, including Alzheimer's disease, multiple sclerosis, bone fractures, some types of cancer, macular degeneration and glaucoma. An estimated 11 million Americans take statins. With new government recommendations issued last week, millions more are likely to begin taking the drugs, and many who already take...