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Keyword: telomeres

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  • At-home telomere testing is not a reliable marker of aging, researcher says

    06/07/2018 11:43:05 AM PDT · by Red Badger · 22 replies
    www.sciencenews.org ^ | 06/07/2018 | By Cori Vanchieri
    Companies pledge to tell you your cellular age from a drop of blood. Don’t be so sure Stay younger, longer. Great idea. But direct-to-consumer test kits that promise to gauge a person’s biological age by analyzing a drop of blood are not worth the $100 or so investment, says oncologist Mary Armanios. The tests measure the length of telomeres, the bits of DNA that cap and protect the ends of chromosomes. But the consumer tests are unreliable and can be misinterpreted, Armanios says. “These kinds of tests can do harm, suggesting there is something wrong when there isn’t,” says the...
  • At the cellular level, a child’s loss of a father is associated with increased stress

    08/25/2017 3:55:42 PM PDT · by PROCON · 3 replies
    The absence of a father — due to incarceration, death, separation or divorce — has adverse physical and behavioral consequences for a growing child. But little is known about the biological processes that underlie this link between father loss and child well-being. In a study (link is external) published July 18 in the journal Pediatrics, a team of FFCWS researchers report that the loss of a father has a significant adverse effect on telomeres, the protective nucleoprotein end caps of chromosomes. At 9 years of age, children who had lost their father had significantly shorter telomeres — 14 percent...
  • Telomere extension turns back aging clock in cultured human cells, study finds

    01/23/2015 2:28:53 PM PST · by Red Badger · 15 replies
    medicalxpress.com ^ | Provided by Stanford University Medical Center
    A new procedure can quickly and efficiently increase the length of human telomeres, the protective caps on the ends of chromosomes that are linked to aging and disease, according to scientists at the Stanford University School of Medicine. Treated cells behave as if they are much younger than untreated cells, multiplying with abandon in the laboratory dish rather than stagnating or dying. The procedure, which involves the use of a modified type of RNA, will improve the ability of researchers to generate large numbers of cells for study or drug development, the scientists say. Skin cells with telomeres lengthened by...
  • Soda causes our cells to age as much as smoking does, study finds

    10/21/2014 7:09:46 PM PDT · by SMGFan · 99 replies
    FoxNews ^ | October 21, 2014
    Drink a 20-ounce soda daily, and you may be causing your cells to age as much as they would if you smoked, a study suggests. Researchers investigated DNA from 5,309 adults, focusing on telomeres, the caps on the ends of our cells' chromosomes, Time reports.
  • Childhood Stress Leaves Genetic Scars

    04/28/2012 3:52:41 PM PDT · by neverdem · 35 replies
    ScienceNOW ^ | 24 April 2012 | Katherine Rowland
    Enlarge Image Early damage. Telomeres (red) are shorter in children who have been abused. Credit: Pasleka/Photo Researchers Inc. Traumatic experiences in early life can leave emotional scars. But a new study suggests that violence in childhood may leave a genetic mark as well. Researchers have found that children who are physically abused and bullied tend to have shorter telomeres—structures at the tips of chromosomes whose shrinkage has been linked to aging and disease. Telomeres prevent DNA strands from unravelling, much like the plastic aglets on a shoelace. When cells divide, these structures grow shorter, limiting the number of times...
  • New blood test can show how long you will live.

    05/16/2011 10:23:24 AM PDT · by Red Badger · 58 replies
    www.wtam.com ^ | 05-16-2011 | Staff
    MENLO PARK, Calif., May 13 (UPI) -- A blood test that measures the length of a person's telomeres -- a predictor of longevity -- may be available soon, U.S. and Spanish researchers say. "Knowing whether our telomeres are a normal length or not for a given chronological age will give us an indication of our health status and of our physiological 'age' even before diseases appear," Maria A. Blasco, who heads the Telomeres and Telomerase Group at the Spanish National Cancer Research Center and who co-founded the company Life Length, told Scientific American. Telomeres are caps on the ends of...
  • The Curious Case of the Backwardly Aging Mouse

    12/04/2010 10:06:50 AM PST · by neverdem · 24 replies
    ScienceNOW ^ | 29 November 2010 | Jennifer Carpenter
    Enlarge Image Golden years. Mice without active telomerase (right) look much older than those with the enzyme (left). Credit: Mariela Jaskelioff/Harvard Medical School In F. Scott Fitzgerald's short story, "The Curious Case of Benjamin Button," an old man gets younger with each passing day, a fantastic concept recently brought to life on film by Brad Pitt. In a lab in Boston, a research team has used genetic engineering to accomplish something similarly curious, turning frail-looking mice into younger versions of themselves by stimulating the regeneration of certain tissues. The study helps explain why certain organs and tissues break down...
  • Fish oil slows burn of genetic fuse in ageing, say scientists

    01/19/2010 2:02:57 PM PST · by neverdem · 68 replies · 2,532+ views
    guardian.co.uk ^ | 19 January 2010 | NA
    Omega-3 fatty acids from fish oils have a direct effect on biological ageing, US research suggests Fish oil may be the true elixir of youth, according to new evidence of its effect on biological ageing. Omega-3 fatty acids from fish oil preserve the genetic "fuse" that determines the lifespan of cells, say scientists. The discovery, made in heart disease patients, may explain many of the claimed health benefits of omega-3. Taking fish oil supplements is said to protect against heart disease, improve survival rates after a heart attack, reduce mental decline in old age and help to prevent age-related changes...
  • People who look young for their age 'live longer'

    12/14/2009 8:44:07 AM PST · by LibWhacker · 32 replies · 1,210+ views
    BBC ^ | 12/14/09
    People blessed with youthful faces are more likely to live to a ripe old age than those who look more than their years, work shows. Danish scientists say appearance alone can predict survival, after they studied 387 pairs of twins. The researchers asked nurses, trainee teachers and peers to guess the age of the twins from mug shots. Those rated younger-looking tended to outlive their older-looking sibling, the British Medical Journal reports. Survival advantageThe researchers also found a plausible biological explanation for their results. Key pieces of DNA called telomeres, which indicate the ability of cells to replicate, are also...
  • Telomeres, Telomerase and Cancer

    10/05/2009 9:42:59 PM PDT · by neverdem · 16 replies · 993+ views
    Scientific American ^ | October 5, 2009 | Carol W. Greider and Elizabeth H. Blackburn
    An unusual enzyme called telomerase acts on parts of chromosomes known as telomeres. The enzyme has recently been found in many human tumors and is being eyed as a new target for cancer therapyEditor's note: We are posting the main text of this article from the February 1996 issue of Scientific American for all our readers because the authors have won the 2009 Nobel Prize in Physiology or Medicine. Subscribers to the digital archive may obtain a full PDF version, complete with artwork and captions. Often in nature things are not what they seem. A rock on the seafloor may...
  • Extinct Ibex Clone Dies at Birth

    02/14/2009 7:52:25 AM PST · by GodGunsGuts · 63 replies · 2,162+ views
    ICR ^ | February 14, 2009 | Brian Thomas, M.S.
      Extinct Ibex Clone Dies at Birth by Brian Thomas, M.S.* The last of a type of wild mountain goat was found dead in the mountains of northern Spain in 2000. The Pyrenean ibex, characterized by its curved horns, was officially declared extinct, but not before tissue samples were collected and preserved in liquid nitrogen.Scientists used DNA extracted from the samples and, replacing the genetic material in eggs from domestic goats, cloned a female Pyrenean ibex—the first extinct animal to be cloned. Unfortunately, the clone died shortly after birth “due to physical defects in its lungs. Other cloned animals, including...
  • Sedentary Life 'Speeds Up Ageing'

    01/29/2008 1:43:38 PM PST · by blam · 19 replies · 675+ views
    BBC ^ | 1-29-2008
    Sedentary life 'speeds up ageing' There is now another good reason for regular exercise, say researchers Leading a sedentary lifestyle may make us genetically old before our time, a study suggests. A study of twins found those who were physically active during their leisure time appeared biologically younger than their sedentary peers. The researchers found key pieces of DNA called telomeres shortened more quickly in inactive people. It is thought that could signify faster cellular ageing. The King's College London study appears in Archives of Internal Medicine. An active lifestyle has been linked to lower rates of cardiovascular disease, type...
  • People With Moles Age More Slowly Than Others

    07/10/2007 6:10:40 PM PDT · by blam · 45 replies · 2,608+ views
    People with moles age more slowly than others Last Updated: 1:43am BST 11/07/2007 People who seem to stay younger for longer are also likely to have more moles, research released yesterday suggests. A study of twins found a striking correlation between high numbers of moles and a biological marker for slow ageing. As a result, people with a lot of moles might be expected to live longer than those who have very few, despite facing a greater risk of skin cancer. Dr Veronique Bataille, from the Twin Research Unit at King's College London, who led the study said: "The results...
  • Coming To A Bad End: Lost Chromosome Tips Linked To Heart problems

    01/19/2007 4:24:56 PM PST · by blam · 10 replies · 482+ views
    Science News ^ | 1-20-2007 | Nathan Seppa
    Coming to a Bad End: Lost chromosome tips linked to heart problems Nathan Seppa The prime risk factors for heart disease are well known—obesity, smoking, elevated cholesterol, and high blood pressure. Yet many people with these warning signs develop heart problems, while others don't. This observation indicates that yet-unrecognized factors must also influence risk. A new study finds that the sequence-repeating sections of DNA called telomeres, which protect the ends of chromosomes, might play a role. Middle-aged men with long telomeres are only half as likely to develop heart disease as are men of the same age with short telomeres,...
  • Shrinking Telomeres Linked To Heart Disease

    01/12/2007 3:45:48 PM PST · by blam · 15 replies · 510+ views
    New Scientist ^ | 1-12-2007 | Michael Day
    Shrinking telomeres linked to heart disease 00:01 12 January 2007 NewScientist.com news service Michael Day The gradual erosion of telomeres – the strands of DNA that cap our chromosomes and wear away with each cell division – may play a pivotal role in heart disease. People who go on to have heart attacks have much shorter telomeres than those who remain healthy, a major new study has shown. Researchers from Leicester and Glasgow Universities in the UK took blood samples from 484 middle-aged men with moderately raised cholesterol, plus 1058 control subjects. They compared the telomere lengths in their white...
  • The Prophet of Immortality

    12/11/2004 8:31:49 AM PST · by Momaw Nadon · 24 replies · 1,831+ views
    Popular Science ^ | January 2005 Issue | Joseph Hooper
    Controversial theorist Aubrey de Grey insists that we are within reach of an engineered cure for aging. Are you prepared to live forever? On this glorious spring day in Cambridge, England, the heraldic flags are flying from the stone towers, and I feel like I could be in the 17th century—or, as I pop into the Eagle Pub to meet University of Cambridge longevity theorist Aubrey de Grey, the 1950s. It was in this pub, after all, that James Watson and Francis Crick met regularly for lunch while they were divining the structure of DNA and where, in February 1953,...
  • Too Much Stress May Give Your Genes Gray Hair

    11/29/2004 11:19:23 PM PST · by neverdem · 31 replies · 4,431+ views
    NY Times ^ | November 30, 2004 | BENEDICT CAREY
    Some stressful events seem to turn a person's hair gray overnight. Now a team of researchers has found that severe emotional distress - like that caused by divorce, the loss of a job, or caring for an ill child or parent - may speed up the aging of the body's cells at the genetic level. The findings, being reported today, are the first to link psychological stress so directly to biological age. The researchers found that blood cells from women who had spent many years caring for a disabled child were, genetically, about a decade older than those from peers...
  • How likely is human extinction?

    04/14/2004 6:15:04 AM PDT · by Momaw Nadon · 519 replies · 1,986+ views
    Mail & Guardian Online ^ | Tuesday, April 13, 2004 | Kate Ravilious
    Every species seems to come and go. Some last longer than others, but nothing lasts forever. Humans are a relatively recent phenomenon, jumping out of trees and striding across the land around 200 000 years ago. Will we persist for many millions of years to come, or are we headed for an evolutionary makeover, or even extinction? According to Reinhard Stindl, of the Institute of Medical Biology in Vienna, the answer to this question could lie at the tips of our chromosomes. In a controversial new theory he suggests that all eukaryotic species (everything except bacteria and algae) have an...