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Keyword: type2diabetes

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  • Arterial Function Deteriorates on Atkins Diet

    09/05/2009 5:10:07 PM PDT · by neverdem · 75 replies · 2,667+ views
    Family Practice News ^ | 1 August 2009 | NEIL OSTERWEIL
    BOSTON — Proponents of the Atkins low-carbohydrate/high saturated fat diet say that you can have your steak and eat it, too, and still lose weight. But the adverse metabolic consequences are too heavy a price to pay, Australian investigators reported at a symposium sponsored by the International Atherosclerosis Society. After 1 year, overweight and obese patients randomly assigned to the Atkins diet or to a low-saturated-fat, high-carbohydrate diet lost similar amounts of weight. But patients on the Atkins diet had a deterioration in flow-mediated arterial dilatation, a marker for cardiovascular disease, and higher levels of LDL cholesterol than at baseline,...
  • Allergy meds slim down obese mice

    08/03/2009 8:38:35 PM PDT · by neverdem · 24 replies · 1,345+ views
    Science News ^ | July 27th, 2009 | Jenny Lauren Lee
    Animal study shows over-the-counter medications lower weight and treat type 2 diabetes Over-the-counter allergy medications turn obese, diabetic mice into healthy, normal-weight mice, researchers report. The new research focuses on mast cells, immune system players critical to the inflammatory response involved in allergies. The study appears along with three other independent studies in the July 26 online Nature Medicine that show a connection between type 2 diabetes and the immune system. “Certainly the study is very exciting,” says George King of Harvard University’s Joslin Diabetes Center in Boston, who was not involved in the research. “It’s the first type to...
  • Creating Fat That Makes You Fit

    07/31/2009 11:12:03 PM PDT · by neverdem · 11 replies · 836+ views
    ScienceNOW Daily News ^ | 29 July 2009 | Cassandra Willyard
    Enlarge ImageGood fat. These engineered brown fat cells were converted from mouse skin connective tissue cells.Credit: Shingo Kajimura Eating grapefruit, climbing stairs, counting carbs--you've tried everything to shed the extra pounds. But still that stubborn paunch persists. Researchers might be one step closer to a solution for this persistent fat. They have found a way to turn ordinary skin cells into a type of fat that burns rather than stores calories. These cells might one day be used to help curb our rapidly expanding waistlines. When most people think of body fat, they picture the whitish goo in love...
  • Antioxidants from black tea may aid diabetics (Type IIs)

    07/30/2009 12:27:02 AM PDT · by neverdem · 9 replies · 810+ views
    foodnavigator.com ^ | 29-Jul-2009 | Stephen Daniells
    Polysaccharides from black tea may blunt the spike in sugar levels after a meal more than similar compounds from green and oolong tea, and offer potential to manage diabetes, says a new study. The black tea polysaccharides also exhibited the greatest activity for scavenging free radicals, which are linked to development of diseases such as cancer and rheumatoid arthritis, according to new findings published in the Journal of Food Science. Interest in tea and its constituents has bloomed in recent years, with the greatest focus on the leaf’s polyphenol content. Green tea contains between 30 and 40 per cent of...
  • Genotyping Reveals CHD Risk in Type 2 Group

    01/24/2009 11:56:17 AM PST · by neverdem · 6 replies · 240+ views
    Family Practice News ^ | 1 January 2009 | BRUCE JANCIN
    NEW ORLEANS — The cardiovascular mortality rate was more than fivefold higher in type 2 diabetic patients who possessed the haptoglobin 2-2 genotype than in those who did not in a large, prospective, Israeli study. Another analysis based on the same study population showed that tight glycemic control reduced the incidence of myocardial infarction—but only in those type 2 diabetic patients with the haptoglobin 2-2 genotype. Taken together, these findings suggest an important role for haptoglobin genotyping in assessing cardiovascular risk and guiding management strategies in patients with type 2 diabetes, Dr. Uzi Milman said at the annual scientific sessions...
  • Fructose -- Found In High-fructose Corn Syrup, Sugar -- Sets Table For Weight Gain Without Warning

    10/19/2008 5:55:46 PM PDT · by fightinJAG · 113 replies · 2,708+ views
    Science Daily ^ | Oct 19, 2008 | Staff
    ScienceDaily (Oct. 19, 2008) — Eating too much fructose can induce leptin resistance, a condition that can easily lead to becoming overweight when combined with a high-fat, high-calorie diet, according to a new study with rats. Although previous studies have shown that being leptin resistant can lead to rapid weight gain on a high-fat, high-calorie diet, this is the first study to show that leptin resistance can develop as a result of high fructose consumption. The study also showed for the first time that leptin resistance can develop silently, that is, with little indication that it is happening. The study...
  • Risk profile for diabetes - Study finds link to high levels of the protein fetuin-A

    07/08/2008 6:04:33 PM PDT · by neverdem · 4 replies · 98+ views
    Science News ^ | July 8th, 2008 | Nathan Seppa
    Elderly people with excess amounts of the protein fetuin-A are more likely than others to develop type 2 diabetes, a new study finds. Because earlier work showed that the protein may interfere with the action of insulin, the new findings potentially implicate fetuin-A in diabetes and suggest the protein may make a good target for drug therapy. Scientists have found fetuin-A tantalizing ever since lab experiments showed it competed with insulin to bind to receptor proteins on cells. By doing so, fetuin-A seems to crowd out insulin and prevent it from making glucose available to muscle cells. “We don’t understand...
  • Intensive Glycemic Control Fails to Cut Cardiovascular Risk: Focus on blood pressure, lipid changes.

    06/27/2008 3:23:46 PM PDT · by neverdem · 5 replies · 188+ views
    Family Practice News ^ | 15 June 2008 | SHERRY BOSCHERT
    (San Francisco Bureau) SAN FRANCISCO — Lowering hemoglobin A1c levels below currently recommended levels did not reduce the risk of macrovascular events in high-risk patients with established type 2 diabetes in two large studies, and significantly increased the risk of death in one of the studies. Providers should focus on managing blood pressure and lipid levels to reduce cardiovascular risk in patients with type 2 diabetes who are at high risk for macrovascular complications, and stick to the currently recommended goal of an HbA1c level between 7% and 7.9%, several investigators suggested during a press conference held at the annual...
  • Nutrition: Mediterranean Diet May Cut Diabetes Risk

    06/13/2008 1:11:16 AM PDT · by neverdem · 1 replies · 84+ views
    NY Times ^ | June 10, 2008 | NICHOLAS BAKALAR
    Vital Signs Sticking to the Mediterranean diet — rich in olive oil, grains, fruits, nuts, vegetables and fish, and low in meats and dairy — may lower the risk for diabetes. Scientists followed 13,380 healthy Spanish university graduates for an average of four and a half years, tracking their dietary habits and confirming new cases of diabetes through medical records. The study was published online May 29 in The British Medical Journal. The researchers ranked the strictness of adherence to the diet on a 10-point scale, and found that those with the highest scores reduced their relative risk of diabetes...
  • Aggressive approach to diabetes proves harmful

    06/06/2008 10:48:18 PM PDT · by neverdem · 8 replies · 457+ views
    Nature News ^ | 6 June 2008 | Heidi Ledford
    Attacking blood sugar levels with high drug doses can be dangerous. Some diabetics who aggressively push down their blood sugar levels may encounter more health problems.Punchstock Patients with type 2 diabetes, a high risk of cardiovascular disease, and who use aggressive measures to reduce their blood sugar levels could actually be shortening their lives, according to a large clinical trial. The results contradict the established theory that diabetics benefit from driving down their excessively high blood sugar levels as forcibly as possible. The trial, part of ACCORD (Action to Control Cardiovascular Risk in Diabetes), made headlines earlier this year when...
  • Obesity Threatens a Generation - 'Catastrophe' of Shorter Spans, Higher Health Costs

    05/18/2008 1:13:55 PM PDT · by neverdem · 54 replies · 337+ views
    Washington Post ^ | May 17, 2008 | Susan Levine and Rob Stein
    An epidemic of obesity is compromising the lives of millions of American children, with burgeoning problems that reveal how much more vulnerable young bodies are to the toxic effects of fat. In ways only beginning to be understood, being overweight at a young age appears to be far more destructive to well-being than adding excess pounds later in life. Virtually every major organ is at risk. The greater damage is probably irreversible. Doctors are seeing confirmation of this daily: boys and girls in elementary school suffering from high blood pressure, high cholesterol and painful joint conditions; a soaring incidence of...
  • Diabetes Study Partially Halted After Deaths

    02/07/2008 8:03:26 PM PST · by neverdem · 37 replies · 80+ views
    NY Times ^ | February 7, 2008 | GINA KOLATA
    For decades, researchers believed that if people with diabetes lowered their blood sugar to normal levels, they would no longer be at high risk of dying from heart disease. But a major federal study of more than 10,000 middle-aged and older people with Type 2 diabetes has found that lowering blood sugar actually increased their risk of death, researchers reported Wednesday. The researchers announced that they were abruptly halting that part of the study, whose surprising results call into question how the disease, which affects 21 million Americans, should be managed. The study’s investigators emphasized that patients should still consult...
  • Type 2 Diabetes: Genes Linked To Insulin Resistance Identified

    10/27/2007 3:53:03 PM PDT · by neverdem · 14 replies · 104+ views
    New research from University of Alabama at Birmingham identifies two genes that may play a role in insulin resistance, opening a new avenue for researchers searching for treatments for type 2 diabetes and metabolic syndrome. The UAB team found that two genes, NR4A3 and NR4A1, seem to boost insulin sensitivity in muscle tissue. Insulin lowers blood glucose, or sugar, by moving it from the bloodstream into skeletal muscle, where it is metabolized for energy or stored for later use. Type 2 diabetes results from either a shortage of insulin or from de-sensitized muscle that does not respond well to insulin,...
  • The Trouble With Mike (Michael Moore)

    07/15/2007 9:42:48 PM PDT · by americanophile · 17 replies · 948+ views
    We were almost finished editing Citizen Black, our documentary on press baron and former Fairfax owner Conrad Black, convicted at the weekend of business fraud, when my husband and directing partner, Rick Caine, asked me: "What should we do next?" Having just made a film about a conservative, we wanted to rinse our palate and take a look at someone who shared our leftist ideals. Then it hit us: what about Michael Moore? We like his films, we like what he stands for and we loved his Oscar speech. He has long had a soft spot for us Canadians: as...
  • FDA Issues Safety Alert on Diabetes Drug (Avandia)

    05/21/2007 2:42:24 PM PDT · by 2ndDivisionVet · 34 replies · 1,499+ views
    iWon News ^ | May 21, 2007 | MARILYNN MARCHIONE
    The widely prescribed diabetes drug Avandia is linked to a greater risk of heart attack and possibly death, a new scientific analysis revealed, and the U.S. government issued a safety alert Monday. The Food and Drug Administration urged diabetics taking the pill to talk to their doctors, but stopped short of forcing a sharper warning label on the drug sold by GlaxoSmithKline PLC (GSK) of London. More than 6 million people worldwide have taken the drug since it came on the market eight years ago. Pooled results of dozens of studies revealed a 43 percent higher risk of heart attack,...
  • Drug can help prevent Type 2 diabetes

    09/17/2006 6:57:42 PM PDT · by neverdem · 74 replies · 1,311+ views
    Seattle Post-Intelligencer ^ | September 16, 2006 | MARILYNN MARCHIONE AND MARIA CHENG
    ASSOCIATED PRESS The largest diabetes prevention study ever done has found that a drug already used to treat the disease also can help keep "pre-diabetics" from developing it. But many experts say losing weight and exercising remain a safer, cheaper approach. The drug, rosiglitazone, or Avandia, appeared to cut the risk of developing Type 2 diabetes by more than half, doctors reported Friday. Type 2 is the most common form of diabetes, afflicting more than 200 million people worldwide. Avandia also helped restore normal blood-sugar function in many of those who took it. A second part of the study found...
  • Diabetes study finds children at higher risk - Study strengthens warning obesity could shorten life

    07/26/2006 10:20:16 PM PDT · by neverdem · 5 replies · 426+ views
    Seattle Post-Intelligencer ^ | July 26, 2006 | LINDSEY TANNER
    ASSOCIATED PRESS CHICAGO -- Children who get obesity-related diabetes face a much higher risk of kidney failure and death by middle age than people who develop diabetes as adults, a study suggests. The study offers some of the first strong evidence of the consequences of the nation's growing epidemic of type 2 diabetes in children, said Dr. William Knowler, a co-author and researcher with the National Institute of Diabetes and Digestive and Kidney Diseases. The research also lends support to warnings that diabetes and other obesity-related ills are on the verge of shortening average life span in the United States....
  • A Diabetic Battle of the Bulge

    07/24/2006 11:32:15 PM PDT · by neverdem · 5 replies · 920+ views
    Diabetes appears to be written into some people's genes, but with the right diet and exercise, the disease may never surface, according to a new study. Nearly 1 in 10 U.S. adults age 20 and older have diabetes, a condition in which the body cannot properly regulate blood glucose levels, leading to organ disease and other complications. Type 2 diabetes accounts for 90% to 95% of all diabetes cases, and over the past 6 years, researchers have linked a handful of genes to the disease. Most recently a team at deCode Genetics in Reykjavik, Iceland, found that individuals with one...
  • (Vanity) Political Limerick 06-20-2006

    06/20/2006 8:27:45 PM PDT · by grey_whiskers · 288+ views
    grey_whiskers ^ | 06-20-2006 | grey_whiskers
    See for example this thread first. Diabetes is now on the rise It should come as no great surprise that our food and drink helps cause it. Ya think? "Just say NO!" when asked to SuperSize...
  • Chemical in Gardenia Fruit Raises Hopes for Type 2 Diabetes Treatment

    06/09/2006 10:28:01 AM PDT · by Ben Mugged · 30 replies · 1,207+ views
    Scientific American ^ | June 07, 2006 | Unattributed
    Roughly one fifth of older Americans suffer from adult-onset diabetes. This form of the disease, also known as type 2 diabetes, arises when insulin-producing cells in the pancreas fail to make enough of the hormone, or cells in the body become resistant to its influence, causing blood sugar levels to rise. This surge, in turn, can lead to potentially life threatening effects. The Western medicine chest currently holds no cure for type 2 diabetes, though treatments can preserve and prolong life. But taking a cue from traditional Chinese medicine, researchers have uncovered a specific chemical from the fruit of the...
  • Pioneering transplant cures diabetic

    03/09/2005 2:03:32 AM PST · by Crackingham · 31 replies · 2,022+ views
    Times Online ^ | March 09, 2005 | Nigel Hawkes
    A breakthrough in using donor pancreas cells in patients' livers means an end to several injections a day. For the first time, a diabetic patient in Britain has been completely cured by a revolutionary transplant operation. Richard Lane, 61, has been able to abandon the daily insulin injections he has endured for the past 28 years thanks to transplants of pancreas cells from three donors. He is the third patient to be treated at King’s College Hospital in London using a technique developed at the University of Alberta in Canada by a Leeds-born specialist, James Shapiro. The two earlier cases...
  • Fat: The Secret Life of a Potent Cell

    07/05/2004 11:01:06 PM PDT · by neverdem · 9 replies · 996+ views
    NY Times ^ | July 6, 2004 | DENISE GRADY
    They are the building blocks of flab, the wages of cheesecake, the bloated little sacks of grease that make more of us - more than we can fit into our pants. Scorned and despised, they are sucked out surgically by the billions from bulging backsides, bellies and thighs. But they are not without admirers. "Fat cells are beautiful cells to look at," said Dr. Philipp E. Scherer, an associate professor of cell biology and medicine at Albert Einstein College of Medicine in New York. "I've been working with them for 10 years and I still enjoy looking at them." On...