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Keyword: virology

Brevity: Headers | « Text »
  • Soaring MERS Cases in Saudi Arabia Raise Alarms

    05/03/2014 5:59:41 PM PDT · by neverdem · 16 replies
    Science ^ | 2 May 2014 | Kai Kupferschmidt
    Scientists are scrambling to make sense of a sharp increase in reported infections with the deadly Middle East respiratory syndrome (MERS) virus. In April alone, Saudi Arabia and the United Arab Emirates have reported over 200 new cases—more than all MERS-affected countries combined in the preceding 2 years. That has sparked fresh fears that the virus may be about to go on a global rampage. The World Health Organization expressed alarm at the new numbers, and the European Centre for Disease Prevention and Control (ECDC) published an updated risk assessment on 25 April warning European countries to expect more imported...
  • CDC Urged To Investigate Mystery Polio-Like Illness Affecting California Kids

    03/03/2014 3:07:05 PM PST · by neverdem · 35 replies
    CBS San Francisco ^ | February 27, 2014 | NA
    WASHINGTON (CBS / AP) — Democratic Sen. Barbara Boxer asked the federal Centers for Disease Control and Prevention on Thursday to initiate a formal investigation into what has caused polio-like paralysis in about 20 children in California over the past 18 months. Boxer said “we need answers” in her letter to CDC Director Thomas Frieden. In particular, she wants the agency to look into whether the illness can be traced to a virus or environmental factors. She also wants to know whether the agency is aware of similar reports of paralysis nationwide...
  • 5 California Children Infected by Polio-Like Illness

    02/28/2014 9:58:03 PM PST · by neverdem · 33 replies
    LiveScience.com ^ | February 23, 2014 | Cari Nierenberg
    Over a one-year period, five children in California developed a polio-like illness that caused severe weakness or paralysis in their arms and legs, a new case study reports. In two of the children, their symptoms have now been linked with an extremely rare virus called enterovirus-68. Like the poliovirus, which has been eradicated in the U.S. since 1979 thanks to the polio vaccine, strains of enterovirus in rare cases can invade and injure the spine. These are the first reported cases of polio-like symptoms being caused by enterovirus in the United States. During the last decade, outbreaks of polio-like symptoms...
  • Progress Against Hepatitis C, a Sneaky Virus

    02/28/2014 3:07:41 PM PST · by neverdem · 10 replies
    NY Times ^ | February 24, 2014 | J E. Brody
    Forty years ago, a beloved neighbor was bedridden for weeks at a time with a mysterious ailment. She knew only that it involved her liver and that she must never drink alcohol, which would make things worse. It was decades before the cause of these debilitating flare-ups was discovered: a viral infection at first called non-A, non-B hepatitis, then properly identified in 1989 as hepatitis C... --snip-- But with two newly approved drugs and a few more in the pipeline, a new era in treatment of hepatitis C is at hand. These regimens are more effective at curing patients and...
  • Can a foot cream really do battle with HIV?

    10/08/2013 8:30:25 AM PDT · by neverdem · 18 replies
    CNET.com ^ | September 24, 2013 | Elizabeth Armstrong Moore
    A study has found that the antifungal drug Ciclopirox kills HIV in cell cultures -- and the virus doesn't bounce back when the drug is stopped. But the research has yet to be performed on people. A drug commonly prescribed to treat nail fungus appears to come with a not-so-tiny side effect: killing HIV in cell cultures.In a study performed at Rutgers New Jersey Medical School, not only does the drug Ciclopirox rid infectious HIV from cell cultures, but the virus also doesn't bounce back when the drug is withheld. The same group of researchers had previously shown that Ciclopirox...
  • Disarming HIV with a 'Pop'

    10/03/2013 7:38:59 PM PDT · by neverdem · 8 replies
    University Herald ^ | Sep 19, 2013 | NA
    Pinning down an effective way to combat the spread of the human immunodeficiency virus, the viral precursor to AIDS, has long been a challenge for scientists and physicians, because the virus is an elusive one that mutates frequently and, as a result, quickly becomes immune to medication. A team of Drexel University researchers is trying to get one step ahead of the virus with a microbicide they've created that can trick HIV into "popping" itself into oblivion. Previous image Enlarge Close Next image / Like Us on Facebook Its name is DAVEI - which stands for "Dual Action Virolytic Entry...
  • Schumer Calls For More Research Into Tick-Borne Diseases: Late Summer Is Peak Lyme Disease Season

    08/11/2013 3:49:18 PM PDT · by neverdem · 24 replies
    CBS NY ^ | August 11, 2013 | NA
    Late summer is peak Lyme disease season. As a result, Sen. Charles Schumer has urged the U.S. Centers for Disease Control and Prevention to study new and potentially fatal tick-borne illnesses.The New York Democrat has urged the CDC to look into two diseases that have already been found in the state.Schumer noted that New York City and on Long Island lead the state in Lyme disease infections. play Schumer Calls For More Research Into Tick-Borne DiseasesWCBS 880's Monica Miller Reports In addition to Lyme disease, ticks are known to carry Babesiosis, Powassan virus and Borrelia miyamotoi.Schumer said those diseases are...
  • Camels May Transmit New Middle Eastern Virus

    08/08/2013 5:33:58 PM PDT · by BenLurkin · 27 replies
    sciencemag.org ^ | 2013-08-08 15:00
    Ever since people in the Middle East started dying of a mysterious new infection last year, scientists have been trying to pinpoint the source of the outbreak. Now they may finally have found a clue in an unlikely population: retired racing camels.
  • Colorado man’s fatal West Nile infection likely came from blood transfusion

    08/08/2013 12:58:09 PM PDT · by neverdem · 3 replies
    KDVR.com ^ | August 8, 2013 | Matt Farley
    DENVER — A Colorado man who died of West Nile virus last year was likely infected through a blood transfusion, a report from the Centers for Disease Control and Prevention found. The man, who was undergoing treatment for non-Hodgkin’s lymphoma, began developing West Nile symptoms after 29 days in the hospital, sharply narrowing the number of ways he could have been exposed to the virus, according to the CDC’s Morbidity and Mortality Weekly Report. He died after 47 days in the hospital. Eighteen days prior to showing symptoms, the patient received a blood transfusion that health officials now believe contained...
  • Herpes Virus Blasts DNA into Human Cells, Says New Study

    07/29/2013 9:24:33 PM PDT · by neverdem · 3 replies
    Sci-News.com ^ | Jul 25, 2013 | NA
    Herpes simplex virus 1 has an internal pressure eight times higher than a car tire, and uses it to literally blast its DNA into human cells, according to a new study published online in the Journal of the American Chemical Society.Dr Alex Evilevitch and his colleagues provide the first experimental evidence of a high internal pressure of tens of atmospheres within Herpes simplex virus 1, resulting from the confined genome. NPC – nuclear pore complex (Bauer DW et al) The study provides the first experimental evidence of high internal pressure within a virus that infects humans – a phenomenon previously...
  • Can Dangerous Bird Flu Virus Fly Between Humans?

    07/19/2013 2:12:22 PM PDT · by neverdem · 7 replies
    ScienceNOW ^ | 18 July 2013 | Jon Cohen
    Enlarge Image Air travel. Ferret studies show that H7N9 can move via respiratory droplets from intentionally infected animals in one cage to their neighbors. Credit: Sander Herfst Since a new bird flu virus began sickening and killing people in China in March, one of the most pressing questions has been whether the virus, H7N9, would easily spread from human to human, possibly kicking off a global pandemic. Fortunately, no convincing signs of such transmission surfaced, and the outbreak—which led affected Chinese cities to close poultry markets and cull birds—seems to have ground to a halt. But three new studies...
  • Giant viruses open Pandora's box

    07/19/2013 1:28:41 PM PDT · by neverdem · 40 replies
    Nature News ^ | 18 July 2013 | Ed Yong
    Genome of largest viruses yet discovered hints at 'fourth domain' of life. The organism was initially called NLF, for “new life form”. Jean-Michel Claverie and Chantal Abergel, evolutionary biologists at Aix-Marseille University in France, found it in a water sample collected off the coast of Chile, where it seemed to be infecting and killing amoebae. Under a microscope, it appeared as a large, dark spot, about the size of a small bacterial cell. Later, after the researchers discovered a similar organism in a pond in Australia, they realized that both are viruses — the largest yet found. Each is around...
  • Rinderpest research restarts

    07/16/2013 11:05:34 PM PDT · by neverdem · 9 replies
    Nature News ^ | 16 July 2013 | Declan Butler
    As moratorium lifts, oversight is put in place to assess studies on eradicated cattle virus. Research is set to resume on the rinderpest virus, the cause of a deadly cattle disease that was declared eradicated in 2011 and has been off limits for study ever since. The moratorium — part of efforts to guard against accidental or intentional release of virus that could reintroduce the disease — was lifted on 10 July and replaced by a new international oversight system for such research. In its heyday, the disease — the only one other than smallpox to be eradicated from nature...
  • WHO Convenes Emergency Committee on MERS Virus

    07/08/2013 11:25:27 PM PDT · by neverdem · 9 replies
    ScienceInsider ^ | 5 July 2013 | Kai Kupferschmidt
    Enlarge Image Crowd control? Public health experts worry that the annual hajj could increase the incidence of MERS. Credit: Bluemangoa2z/Wikimedia Commons The World Health Organization (WHO) is convening an emergency committee to determine whether the novel coronavirus that emerged in the Middle East last year constitutes a "public health emergency of international concern." Keiji Fukuda, Assistant Director-General for Health Security and Environment at the WHO, announced the move at a press conference today in Geneva. Fukuda said the committee would be drawn from a roster established under International Health Regulations and include experts in public health, epidemiology, virology and...
  • New Viruses Found in Asia and Africa Tentatively Linked to Neurological Disease

    06/26/2013 11:45:25 PM PDT · by neverdem · 3 replies
    ScienceNOW ^ | 20 June 2013 | Mara Hvistendahl and Martin Enserink
    A mysterious group of viruses known for their circular genome has been detected in patients with severe disease on two continents. In papers published independently this week, researchers report the discovery of agents called cycloviruses in Vietnam and in Malawi. The studies suggest that the viruses—one of which also widely circulates in animals in Vietnam—could be involved in brain inflammation and paraplegia, but further studies are needed to confirm a causative link. The discovery in Vietnam grew out of a frustrating lack of information about the causes of some central nervous system (CNS) infections such as encephalitis and meningitis, which...
  • 'Universal' flu vaccine effective in animals

    05/23/2013 10:32:31 AM PDT · by neverdem · 12 replies
    Nature News ^ | 22 May 2013 | Ed Yong
    Self-assembling nanoparticles could make updating seasonal vaccines easier. Under the microscope, they look like simple jacks, with eight spikes jutting out of a central ball. But these protein nanoparticles are science's latest weapon against influenza: a new breed of flu vaccine that provides better and broader protection than commercially available ones — at least in animal tests. Current flu vaccines use inactivated whole viruses and must be regularly remade to target the strains most likely to cause illness in the coming year. But the new nanoparticles would require fewer updates because they induce the production of antibodies that neutralize a...
  • 'MERS' Makes Its Debut in a Scientific Journal

    05/19/2013 3:24:36 PM PDT · by neverdem · 18 replies
    ScienceInsider ^ | 15 May 2013 | Martin Enserink
    Enlarge Image It shall be called. Researchers are proposing a name for new coronavirus (yellow): Middle East Respiratory Syndrome Coronavirus (MERS-CoV). Credit: NIAID/RML A group of coronavirus experts has published its proposal to name a new, deadly virus after the Middle East, the region where it originates. In a short paper published online today by the Journal of Virology, the Coronavirus Study Group (CSG), along with several other scientists, recommends calling the pathogen Middle East Respiratory Syndrome Coronavirus (MERS-Cov). As ScienceInsider reported last week, the group, part of the International Committee on Taxonomy of Viruses, hopes to end confusion...
  • WHO says new bird strain is "one of most lethal" flu viruses

    04/24/2013 2:45:02 PM PDT · by neverdem · 34 replies
    Reuters ^ | April 24, 2013 | Sui-Lee Wee and Kate Kelland
    A new bird flu strain that has killed 22 people in China is "one of the most lethal" of its kind and transmits more easily to humans than another strain that has killed hundreds since 2003, a World Health Organization (WHO) expert said on Wednesday. The H7N9 flu has infected 108 people in China since it was first detected in March, according to the Geneva-based WHO. Although it is not clear exactly how people are being infected, experts say they see no evidence so far of the most worrisome scenario - sustained transmission between people. An international team of scientists...
  • Researchers see antibody evolve against HIV

    04/04/2013 9:05:51 PM PDT · by neverdem · 15 replies
    Nature News ^ | 03 April 2013 | Erika Check Hayden
    Study could aid development of more effective vaccines. For the first time, scientists have tracked in a patient the evolution of a potent immune molecule that recognizes many different HIV viruses. By revealing how these molecules — called broadly neutralizing antibodies — develop, the research could inform efforts to make vaccines that elicit similar antibodies that can protect people from becoming infected with HIV. The researchers, led by Barton Haynes of Duke University School of Medicine in Durham, North Carolina, found that broadly neutralizing antibodies developed only after the population of viruses in the patient had diversified — something that...
  • How herpesvirus invades nervous system

    03/30/2013 3:08:29 PM PDT · by neverdem · 4 replies
    Biology News Net ^ | March 28, 2013 | NA
    Northwestern Medicine scientists have identified a component of the herpesvirus that "hijacks" machinery inside human cells, allowing the virus to rapidly and successfully invade the nervous system upon initial exposure. Led by Gregory Smith, associate professor in immunology and microbiology at Northwestern University Feinberg School of Medicine, researchers found that viral protein 1-2, or VP1/2, allows the herpesvirus to interact with cellular motors, known as dynein. Once the protein has overtaken this motor, the virus can speed along intercellular highways, or microtubules, to move unobstructed from the tips of nerves in skin to the nuclei of neurons within the nervous...
  • Distinctive virus behind mystery horse disease

    03/18/2013 7:59:48 PM PDT · by neverdem · 10 replies
    Nature News ^ | 18 March 2013 | Ed Yong
    Origin of Theiler hepatitis was a century-old puzzle. For almost 100 years, veterinarians have puzzled over the cause of Theiler disease, a mysterious type of equine hepatitis that is linked to blood products and causes liver failure in up to 90% of afflicted animals. A team of US scientists has now discovered that the disease is caused by a virus that shares just 35% of its amino acid sequences with its closest-known relative. The team named it Theiler disease-associated virus (TDAV), and published the discovery in the Proceedings of the National Academy of Sciences1. Led by Amy Kistler at the...
  • The next big thing in mass spectrometry

    03/17/2013 2:58:54 PM PDT · by neverdem · 27 replies
    Chemistry World ^ | 8 March 2013 | David Bradley
    It's not quite the ‘elephant in the room’, but an 18 megadalton viral assembly is perhaps the biggest thing in the mass spectrometer (MS). Dutch and US researchers have used quadrupole time-of-flight (QToF) native MS to investigate intact capsids from a bacteriophage – a virus that infects bacteria. While there is theoretically no upper limit on the mass of a particle that might be analysed using ToF MS, the work is far from trivial in breaking through the record.The late John Fenn shared the 2002 Nobel prize in chemistry for his pioneering work on electrospray ionisation techniques in mass...
  • New direction for flu drugs

    02/23/2013 11:14:06 PM PST · by neverdem · 30 replies
    Chemistry World ^ | 21 February 2013 | James Urquhart
    An international team of researchers has developed a new class of anti-flu drug that could prevent new virus strains developing resistance and help control future pandemics while more effective vaccines are prepared. Each year, flu viruses cause up to five million cases of severe illness worldwide, resulting in up to 500 000 deaths.The preferred drug treatments for flu – neuraminidase inhibitors including Tamiflu (oseltamivir) and Relenza (zanamivir) – treat infection by stopping the viral surface enzyme neuraminidase from interacting with its natural substrate, sialic acid. It is this interaction that releases the virus from an infected cell and allows it...
  • Mystery of fatal raccoon disease solved

    01/22/2013 10:21:49 PM PST · by neverdem · 24 replies
    San Francisco Chronicle ^ | January 14, 2013 | Ellen Huet
    As someone who cares for about 100 raccoons a year, Melanie Piazza knows that a listless, placid raccoon is not a healthy one. "A lot of the calls were, 'There's a raccoon sitting on my porch and he hasn't moved all day, and I open the door and he doesn't move,' and that's not normal," said Piazza, the director of animal care at WildCare, a wildlife refuge in San Rafael and one of several Bay Area care centers baffled in recent years by a rise in strange raccoon behavior. The centers would occasionally collect raccoons like this and try to...
  • Vipers Go Viral

    10/09/2012 8:47:41 PM PDT · by neverdem · 8 replies
    ScienceNOW ^ | 5 October 2012 | Gisela Telis
    Enlarge Image Harboring trouble. A new study suggests venomous cottonmouths may harbor Eastern equine encephalitis virus through the winter. Credit: iStockphoto/Thinkstock Every year as the days grow warmer, the Eastern equine encephalitis virus (EEEV) reemerges along the eastern coast of the United States, where it causes devastating disease in horses and, more rarely, humans. Scientists have long wondered how the virus, which is transmitted by the bite of an infected mosquito, survives the cold, mosquito-killing North American winters. Now, a new study suggests that snakes harbor the virus through the winter, but experts disagree on whether the finding clinches...
  • Diary From The HMNZ Tahiti During The 1918 Pandemic

    10/08/2012 12:00:43 PM PDT · by neverdem · 19 replies
    Avian Flu Diary ^ | OCTOBER 08, 2012 | Michael Coston
    For years historians, epidemiologists, and virologists have been attempting to peel back the cobwebs of time in order to analyze the deadliest pandemic in human history; the 1918 Spanish Flu Pandemic. John Barry’s The Great Influenza: The Epic Story of the Greatest Plague in History, has probably done more to reawaken memories of that awful time than any other source, but many gaps in our knowledge remain. Jeffrey K. Taubenberger and David Morens - both researchers at NIAID – have added considerably to our understanding of the H1N1 virus and the events surrounding its emergence. Taubenberger was the first to...
  • A 3-Year Search Uncovers Novel Hemorrhagic Fever Virus

    09/29/2012 1:13:58 AM PDT · by neverdem · 12 replies
    ScienceNOW ^ | 27 September 2012 | Jon Cohen
    A newly discovered virus from the family that causes rabies may be responsible for three linked cases of hemorrhagic fever in the Democratic Republic of the Congo more than 3 years ago. Ebola virus, Marburg virus, Lassa fever, Rift Valley fever, yellow fever, and dengue are well known viruses from four different viral families that can cause hemorrhagic fever. But an international team of researchers report in PLoS Pathogens today that the rhabdovirus family, which typically causes brain swelling or flulike disease, can join the club of hemorrhagic fever agents, which are among the most virulent pathogens known to humans....
  • A SARS-like Virus Has Been Detected In The Middle East

    09/24/2012 2:45:26 PM PDT · by blam · 34 replies
    TBI ^ | 9-24-2012 | Joshua Berlinger
    A SARS-like Virus Has Been Detected In The Middle East Joshua BerlingerSeptember 24, 2012 Health experts are monitoring a SARS-like virus that has killed one individual and hospitalized another in the Middle East. The World Health Organization (WHO) said on Monday that the 49-year-old Qatari man was admitted to an intensive care unit in Doha on September 7, suffering from "acute respiratory infection and kidney failure" after traveling to Saudi Arabia. He was transferred to Britain by air ambulance on September 11. The British Health Protection Agency also released a statement on Sunday addressing the infections. The WHO said virus...
  • The hidden threat of West Nile virus - Researchers probe possible link with kidney disease.

    09/21/2012 4:33:01 PM PDT · by neverdem · 9 replies
    NATURE NEWS ^ | 18 September 2012 | Amy Maxmen
    This year is on track to be the worst on record for West Nile virus in the United States. As of 11 September, more than 2,600 new cases, including 118 deaths, had been reported from across the country to the US Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia. Symptoms of the mosquito-borne disease range from none (in most people) to life-threatening brain inflammation, and it can leave survivors with long-term disabilities including paralysis and fatigue. Researchers are now investigating suggestions that even mild infections may leave another lasting burden — kidney disease. “We are early in our...
  • What Makes Bat Viruses So Deadly?

    08/05/2012 12:47:53 AM PDT · by neverdem · 7 replies
    ScienceNOW ^ | 2 August 2012 | Dennis Normile
    Enlarge Image Safe haven. Bats harbor viruses both dangerous and benign for other animals. Credit: CSIRO When it comes to harboring viruses deadly to humans, bats are grand champions. The flying mammals are the reservoir for everything from rabies to Ebola. Now, scientists have found a new virus hosted by bats, one that doesn't seem to be able to cause disease in other animals. The discovery may provide clues to what enables some viruses to cause severe disease. The new Cedar virus is named after the town of Cedar Grove in Queensland, Australia, where it was found in 2009....
  • One of Two Hotly Debated H5N1 Papers Finally Published

    05/03/2012 4:31:28 PM PDT · by neverdem · 7 replies
    ScienceNOW ^ | 2 May 2012 | Martin Enserink and Jon Cohen
    Enlarge Image Hot spots. Three mutations in or near hemagglutinin's binding site (yellow) and one on its stalk increased transmissibility. Credit: H.-L. Yen and J. S. M. Peiros, Nature, Adavanced Online Edition, (2012) One of two influenza papers at the center of an intense, 6-month international debate has finally seen the light of day. Today, Nature published a controversial study in ferrets that shows how scientists can engineer an avian influenza strain to transmit between mammals through respiratory droplets such as those created by coughing or sneezing. The 11-page study, led by Yoshihiro Kawaoka of the University of Wisconsin,...
  • 'Junk DNA' Can Sense Viral Infection: Promising Tool in the Battle Between Pathogen and Host

    04/28/2012 3:27:49 AM PDT · by neverdem · 13 replies
    ScienceDaily ^ | Apr. 24, 2012 | NA
    Once considered unimportant "junk DNA," scientists have learned that non-coding RNA (ncRNA) -- RNA molecules that do not translate into proteins -- play a crucial role in cellular function. Mutations in ncRNA are associated with a number of conditions, such as cancer, autism, and Alzheimer's disease. Now, through the use of "deep sequencing," a technology used to sequence the genetic materials of the human genome, Dr. Noam Shomron of Tel Aviv University's Sackler Faculty of Medicine has discovered that when infected with a virus, ncRNA gives off biological signals that indicate the presence of an infectious agent, known as a...
  • Fight Against Measles Appears Stalled

    04/24/2012 10:44:22 PM PDT · by neverdem · 1 replies
    ScienceNOW ^ | 23 April 2012 | Kai Kupferschmidt
    Enlarge Image Credit: D. Cima/American Red Cross Measles deaths dropped dramatically in the first decade of the 21st century, but progress has stalled since 2007, new estimates show. A report from the World Health Organization (WHO), the U.S. Centers for Disease Control and Prevention (CDC), and Pennsylvania State University calculates that global measles deaths fell from 535,000 in 2000 to 139,000 in 2010—an impressive 74% reduction, but short of WHO's goal of 90%. More worryingly, the paper, released in The Lancet today, shows that those numbers have essentially remained flat since 2007. The measles virus is one of the...
  • Bacteria-Killing Viruses Wield an Iron Spike

    02/29/2012 9:02:56 PM PST · by neverdem · 13 replies · 1+ views
    ScienceNOW ^ | 24 February 2012 | Michael Bullwinkle
    Enlarge Image Viral attack. A handful of P1 phages pierce the membrane of an E. coli bacterium, as seen under electron microscopy (left panels) and a 3D reconstruction (right). Credit: Adapted from J. Liu et al., Virology, 417 (1 September 2011) Forget needles in haystacks. Try finding the tip of a needle in a virus. Scientists have long known that a group of viruses called bacteriophages have a knack for infiltrating bacteria and that some begin their attack with a protein spike. But the tip of this spike is so small that no one knew what it was made...
  • Seeing Terror Risk, U.S. Asks Journals to Cut Flu Study Facts (Bird Flu)

    12/20/2011 10:52:01 PM PST · by neverdem · 7 replies · 1+ views
    NY Times ^ | December 20, 2011 | DENISE GRADY and WILLIAM J. BROAD
    For the first time ever, a government advisory board is asking scientific journals not to publish details of certain biomedical experiments, for fear that the information could be used by terrorists to create deadly viruses and touch off epidemics. In the experiments, conducted in the United States and the Netherlands, scientists created a highly transmissible form of a deadly flu virus that does not normally spread from person to person. It was an ominous step, because easy transmission can lead the virus to spread all over the world. The work was done in ferrets, which are considered a good model...
  • Novel strategy stymies SARS et al. (viral replication)

    10/28/2011 11:51:21 AM PDT · by decimon · 4 replies
    LMU Munich ^ | October 28, 2011
    Broad-spectrum antibiotics, which are active against a whole range of bacterial pathogens, have been on the market for a long time. Comparably versatile drugs to treat viral diseases, on the other hand, have remained elusive. Using a new approach, research teams led by Dr. Albrecht von Brunn of LMU Munich and Professor Christian Drosten from the University of Bonn have identified a compound that inhibits the replication of several different viruses, including the highly aggressive SARS virus that is responsible for severe acute respiratory syndrome. The new method exploits the fact that interactions between certain host proteins and specific viral...
  • Respiratory virus jumps from monkeys to humans

    07/17/2011 12:06:38 AM PDT · by neverdem · 16 replies
    Nature News ^ | 14 July 2011 | Zoe Cormier
    Adenovirus remained infectious after crossing species barrier. A class of virus has for the first time been shown to jump from animals to humans — and then to infect other humans. The virus is described in PLoS Pathogens today1. The team that discovered it might also have found the first human to be infected: the primary carer for a colony of titi monkeys (Callicebus cupreus) that suffered an outbreak. The culprit is an adenovirus, one of a class of viruses that cause a range of illnesses in humans, including pneumonia. But this particular strain has never been seen before. It...
  • Discovery of canine hepatitis C virus opens up new doors for research on deadly human pathogen

    06/07/2011 4:32:19 PM PDT · by neverdem · 7 replies
    EurekAlert! ^ | 23-May-2011 | NA
    Contact: Daniela Hernandez dfh2101@columbia.edu 310-991-2391 Columbia University's Mailman School of Public Health In a study to be published online this week in the Proceedings of the National Academy of Sciences, researchers report the discovery of a novel hepatitis C-like virus in dogs. The identification and characterization of this virus gives scientists new insights into how hepatitis C in humans may have evolved and provides scientists renewed hope to develop a model system to study how it causes disease. The research was conducted at the Center for Infection and Immunity (CII) at Columbia University's Mailman School of Public Health, the University...
  • 'Virus-eater' discovered in Antarctic lake

    03/29/2011 3:23:02 PM PDT · by neverdem · 52 replies · 1+ views
    Nature News ^ | 28 March 2011 | Virginia Gewin
    First of the parasitic parasites to be discovered in a natural environment points to hidden diversity. A genomic survey of the microbial life in an Antarctic lake has revealed a new virophage — a virus that attacks viruses. The discovery suggests that these life forms are more common, and have a larger role in the environment, than was once thought. An Australian research team found the virophage while surveying the extremely salty Organic Lake in eastern Antarctica. While sequencing the collective genome of microbes living in the surface waters, they discovered the virus, which they dubbed the Organic Lake Virophage...
  • TRANSITIONAL ORIENTATION

    02/07/2011 3:12:59 PM PST · by James Oscar · 19 replies · 1+ views
    FLU TRACKERS ^ | 2-7-11 | ORIGINAL WORK
    TRANSITIONAL ORIENTATION The last days had dwindled down to a final few. Evil was moving and extremely confident while Good was leaderless. The Middle East was in turmoil and Evil was now in position to finally achieve its only goal - the destruction of mankind. That destruction was to start, to no one's surprise, with the annihilation of Israel. Annihilation was now portable. A few travelers to whom death was an honor would deliver suitcases filled with devices of ultimate horror. Those suitcases had been gathered and assembled from around the world by a cabal that transcended race, religion, culture...
  • THE THIRD WAVE (Sympatric Speciation)

    02/03/2011 7:44:55 AM PST · by James Oscar · 4 replies
    Original Work ^ | 2-2-11 | James Oscar
    THE THIRD WAVE Sympatric Speciation In 2003 a retired biologist took the lead position in sounding the alarm about SARS. Her work would include redefining how information is exchanged in the digital age, educating professionals and laymen alike and creating the new media phenomena now known as the “Flu Blog”. She would later go on to accurately describe the natural host of the Ebola Virus – five years before confirmation of her hypothesis was published. I was fortunate enough to interview her on a wide variety of topics. That conversation has lasted several years. The first four discussions are linked...
  • Chronic Fatigue Syndrome Not Caused by XMRV Virus, Study Finds - U.K. Study Overturns Previous...

    12/22/2010 8:37:48 PM PST · by neverdem · 21 replies · 1+ views
    WebMD Health News ^ | Dec. 20, 2010 | Tim Locke
    U.K. Study Overturns Previous Research Citing Virus as Cause of CFS Reviewed by Rob Hicks, MD Chronic fatigue syndrome is not caused by the virus XMRV, according to new research. A team from University College London, the Wellcome Trust Sanger Institute, and University of Oxford, all in England, says previous research linking the virus to chronic fatigue syndrome (CFS) was flawed because of contamination of mouse cell DNA samples in the laboratory. CFS is a disorder characterized by chronic fatigue lasting six months or longer, with several additional symptoms that may include impaired memory, unrefreshing sleep, muscle pain, sore throat,...
  • Are We Ready For A Biological Attack?

    12/03/2010 8:40:07 PM PST · by neverdem · 15 replies
    Human Events ^ | 12/02/2010 | James A. Joyce
    There has been much discussion by national security experts inside and outside of government as to how Congress and the President should ensure that the United States is safe from a terrorist attack.  But there has been relatively little discussion in comparison as to how we would respond if an attack did occur.  Are we ready for a biological attack on our military or citizenry?  Has the federal government planned for a medical response to an attack?  Are we spending money on the right therapies or vaccines?  Do we even know how to respond to a widespread biological or chemical...
  • THE COMING WAVE (An interview with Mother Abigail - The Conclusion)

    10/13/2010 5:16:24 PM PDT · by James Oscar · 123 replies · 1+ views
    FluTrackers ^ | 10-12-10 | Original Work
    This is the final chapter in my series of interviews with the enigmatic Mother Abigail. It has been the most challenging project of my career. It has also been the most rewarding. I hope that you enjoy the four works and I will briefly recap the first three for those who are just joining us.
  • Fresh hep C hope

    04/25/2010 6:39:22 PM PDT · by neverdem · 6 replies · 512+ views
    Chemistry World ^ | 21 April 2010 | Sarah Houlton
    A new kind of compound to treat hepatitis C is showing promise in early clinical trials. The treatment, being developed by Bristol-Myers Squibb (BMS), was found to be very effective at lowering viral load, both in a Phase I trial published this week in Nature, and in early results of a Phase IIa trial presented at the European Association for the Study of the Liver's annual meeting in Vienna last week.Current HCV therapy is not ideal. The standard treatment is with an interferon and the antiviral agent ribavirin, but is only effective in around half of all patients and is plagued with...
  • Compound found that targets wide range of viruses

    02/01/2010 10:43:22 AM PST · by decimon · 27 replies · 543+ views
    Cell-culture and animal tests show antiviral could provide protection against HIV, Ebola, hepatitis C, herpes and moreGALVESTON, Texas — The development of antibiotics gave physicians seemingly miraculous weapons against infectious disease. Effective cures for terrible afflictions like pneumonia, syphilis and tuberculosis were suddenly at hand. Moreover, many of the drugs that made them possible were versatile enough to knock out a wide range of deadly bacterial threats. Unfortunately, antibiotics have a fundamental limitation: They're useless against viruses, which cause most infectious diseases. Antiviral drugs have proven far more difficult to create, and almost all are specifically directed at a few...
  • Scientists identify new lethal virus in Africa

    05/29/2009 8:29:44 AM PDT · by null and void · 21 replies · 842+ views
    Breitbart/AP ^ | May 28 08:01 PM US/Eastern | MIKE STOBBE
    By AP Medical Writer ATLANTA (AP) - Scientists have identified a lethal new virus in Africa that causes bleeding like the dreaded Ebola virus. The so-called "Lujo" virus infected five people in Zambia and South Africa last fall. Four of them died, but a fifth survived, perhaps helped by a medicine recommended by the scientists. It's not clear how the first person became infected, but the bug comes from a family of viruses found in rodents, ... "This one is really, really aggressive" he said of the virus. ... A paramedic in Lusaka who treated her also became sick, was...
  • Old seasonal flu antibodies target swine flu virus

    05/23/2009 1:26:09 AM PDT · by neverdem · 8 replies · 816+ views
    Nature News ^ | 21 May 2009 | Heidi Ledford
    Lab results could explain why young patients are hardest hit by current H1N1 strain. Antibodies against some seasonal flu strains from prior years may be active against the new H1N1 swine flu currently circulating the globe, a recent study reports. The findings suggest an explanation for why swine flu appears to infect the young more often than the elderly, who are normally more susceptible to seasonal flu viruses.Only 1% of swine flu cases in the United States are in people over the age of 65.CDC The study, published today in the Morbidity and Mortality Weekly Report, analyzed blood samples taken...
  • Genetic analysis of swine flu virus released

    05/23/2009 12:43:38 AM PDT · by neverdem · 11 replies · 796+ views
    Science News ^ | May 22nd, 2009 | Tina Hesman Saey
    Components have existed for years but are combined in a new way Components of the H1N1 swine flu virus have been circulating undetected for years, but the virus combines the bits and pieces in a way never before seen, a detailed genetic analysis reveals. The analysis, published online May 22 in Science, pinpoints the origins of each of the virus’s components. It suggests that current influenza vaccines probably won’t provide protection from the virus, but that the virus is susceptible to some antiviral drugs and will be amenable to new vaccine development. A separate study of the virus’s neuraminidase protein...
  • Mimivirus up close - Scientists investigate structural details of the largest known virus

    04/30/2009 12:58:17 AM PDT · by neverdem · 11 replies · 1,350+ views
    Science News ^ | April 28th, 2009 | Rachel Ehrenberg
    Scientists have zoomed in on mimivirus, the enormous virus with the delicate name that has perplexed scientists since 1992, when it was found living in an amoeba in a water tower in England. “This is like landing on the moon,” says Michael Rossmann of Purdue University in West Lafayette, Ind. Rossmann and an international team of scientists report the results of their reconnaissance online April 27 in PLoS Biology. Mimivirus, full name Acanthamoeba polyphaga Mimivirus, is the largest known virus in the world. Its mass is more than 100 times that of the virus that causes the common cold, says...