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General Information

Differin Gel 0.1% has been approved for the treatment of acne. Differin Gel is a new topical prescription medication that penetrates deeply into hair follicles where it can prevent and reduce blackheads and whiteheads.

Generic Name: adapalene topical (a DAP a leen)
Brand Names: Differin cream and gel

Clinical Results

In controlled clinical trials, Differin Gel was shown to effectively reduce the number and severity of acne lesions after 12 weeks of therapy. Furthermore, the subjects on Differin Gel experienced less skin dryness and skin irritation than those on topical Tretinoin Gel 0.025%. Stinging, burning, peeling, and skin redness associated with retinoid therapy have been a barrier to subjects remaining on their Tretinoin acne medication and achieving successful treatment outcomes.

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