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Keyword: colitis

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  • Danish study finds drug reduces 'forever chemicals' in blood (Bile sequesters reduce by 63%)

    03/01/2024 2:27:20 PM PST · by ConservativeMind · 19 replies
    Medical Xpress / AFP ^ | Feb. 29, 2024 | Morten Lindhardt et al
    A medication for high cholesterol can drastically cut "forever chemicals" (PFAS)—associated with an increased risk of cancer and banned in Europe—in the blood, researchers said. But the drug was not suitable for widespread and prolonged use because of its side effects. A clinical trial with cholestyramine led to a reduction 20 times greater than the normal result without intervention. "The effect of treatment was actually a decrease in the plasma of 63 percent," said Lindhardt. Researchers say the results are promising for treating people who have been exposed to high doses of the "forever chemicals", so called because they tend...
  • Unsaturated fats can help control damaging bouts of inflammation in colitis (Olive oil)

    02/29/2024 9:48:11 PM PST · by ConservativeMind · 14 replies
    Medical Xpress / Yale University / Nature ^ | Feb. 22, 2024 | Bill Hathaway / Autumn G. York et al
    An overly robust immune response to usually harmless germs has been linked to colitis, a potentially severe inflammation of the colon. A study not only reveals that the presence of one class of fatty acids is the hidden villain that quietly triggers this inflammation, but also found that another group of fats—unsaturated fats such as those found in olive oil—can alleviate symptoms of colitis in mice. The cytokine interleukin-10 (IL-10), part of the innate immune system, is essential for suppressing inflammatory responses in the gut. In fact, children born without IL-10 need bone marrow transplants which can produce the cytokine...
  • Body changes detected up to eight years before inflammatory bowel disease diagnosis

    11/15/2023 4:09:11 PM PST · by ConservativeMind · 2 replies
    Researchers have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis. This means the beginnings of inflammatory bowel diseases start a long time before symptoms occur, and in the future may provide an opportunity for doctors to take preventative action before symptoms begin, or prescribe medication when it will be most effective. Crohn's disease and ulcerative colitis are collectively known as inflammatory bowel diseases (IBD). They are incurable conditions which involve excessive inflammation in the gut, leading to symptoms...
  • Help with ulcerative colitis

    10/04/2023 3:21:21 PM PDT · by Allthesaints · 42 replies
    I would appreciate any advise or any ideas to help a young loved one who is suffering terribly with ulcerative colitis. The only relief thus far is from prednisone, which comes with other problems. Prayers please! Thank you in advance.
  • Statins linked to lower risk of colorectal cancer in patients with ulcerative colitis

    09/04/2023 1:22:12 PM PDT · by ConservativeMind · 4 replies
    Cholesterol-lowering statins might protect patients with ulcerative colitis from developing and dying from colorectal cancer. Statin treatment was also associated with a lower risk of death regardless of cause in patients with ulcerative colitis or Crohn's disease. This is according to a study. "Our study suggests that statins can prevent colorectal cancer in patients with inflammatory bowel disease (IBD), which is a high-risk group for this kind of cancer," says Jiangwei Sun. The observational study compared more than 10,500 IBD patients from around the country, of whom half were statin users; the other half of the group, who were matched...
  • Fecal microbiota transplant effective for immune-mediated colitis, finds study (92% clinical remission)

    06/17/2023 5:06:46 PM PDT · by ConservativeMind · 5 replies
    Medical Xpress / HealthDay / Science Translational Medicine ^ | June 16, 2023 | Elana Gotkine / Taylor M. Halsey et al
    For patients with refractory immune checkpoint inhibitor (ICI)-induced colitis, fecal microbiota transplantation (FMT) is an effective treatment, according to a study. Taylor M. Halsey and colleagues, reported a case series of 12 patients with refractory immune-mediated colitis (IMC) who underwent FMT from healthy donors as salvage therapy. All patients had grade 3 or 4 ICI-related diarrhea or colitis that did not respond to standard first- and second-line immunosuppression (corticosteroids and infliximab or vedolizumab). The researchers found that 10 of the 12 patients achieved symptom improvement and three patients required repeat FMT; two of these had no subsequent response. Ninety-two percent...
  • 'Infect and forget': A dose of hookworms could help patients manage inflammatory bowel disease

    06/16/2023 9:47:52 AM PDT · by Red Badger · 23 replies
    Medical Express ^ | by Inflammatory Bowel Diseases
    Credit: Fernandolive on Wikimedia Commons Could a dose of hookworms provide a medication-free alternative to people with inflammatory bowel disease? The Malaghan Institute's Hookworm Therapy team, who recently published the results from their year-long clinical study, think it's possible. Published in Inflammatory Bowel Diseases, the feasibility study found that hookworms were a safe and long-lasting treatment for participants with ulcerative colitis—paving the way for wider clinical studies. The Malaghan Institute has been exploring the potential therapeutic benefits of human hookworms for patients suffering allergic and inflammatory disease for a number of years. This current study was the first of its...
  • Study shows melatonin, commonly used to improve sleep, can aggravate bowel inflammation (Worsens colitis by hurting gut bacteria)

    05/10/2023 12:06:57 PM PDT · by ConservativeMind · 20 replies
    Medical Xpress / FAPESP / Microorganisms ^ | May 9, 2023 | Ricardo Muniz / Jefferson Luiz da Silva et al
    An article shows that melatonin, despite its antioxidant effects and role in regulating sleep cycles, can worsen inflammation of the intestine and impair the action of gut microbiota. Melatonin is popularly known as the "sleep hormone" and is often taken as a so-called food supplement without a doctor's prescription by people with sleep problems. "It's generally thought to be harmless. However, our study shows that the ingestion of melatonin supplement can have adverse effects on health," said Cristina Ribeiro de Barros Cardoso. Melatonin can act as an antioxidant and improve several physiological or pathological conditions. "We started out in this...
  • Psyllium fiber protects against colitis by activating bile acid sensor, researchers find (Improves metabolic syndrome, Crohn's disease and ulcerative colitis (IBD))

    Psyllium fiber protects against ulcerative colitis and suppresses inflammation by activating the bile acid nuclear receptor, a mechanism that was previously unrecognized, according to a study. The findings reveal that psyllium inhibits inflammation that can lead to colitis in mice by increasing serum bile acids, resulting in the activation of the farnesoid X receptor (FXR), a bile acid nuclear receptor. Fiber-rich foods promote intestinal and metabolic health, but the extent of protection varies for each fiber type. It has been unclear whether dietary fiber can benefit severe forms of intestinal inflammation, such as Crohn's disease and ulcerative colitis, which are...
  • New Compound Reverses Gut Inflammation – Acts Like a Master Reset Switch in the Intestines

    12/14/2022 11:13:49 AM PST · by Red Badger · 9 replies
    Scitech Daily ^ | By SALK INSTITUTE - DECEMBER 14, 2022
    Salk Institute researchers have developed a new compound that acts like a master reset switch in the intestines. In a new study, the compound, called FexD, is found to prevent and reverse intestinal inflammation in mouse models of inflammatory bowel disease. New therapeutic has the potential to treat inflammatory bowel disease by targeting a molecule that keeps order in the intestines. Salk Institute scientists have developed a new drug that acts like a master reset switch in the gut. Called FexD, the compound has previously been found to burn fat, lower cholesterol, and ward off colorectal cancer in mice. Now,...
  • The Healing Benefits of Red Meat

    12/01/2022 5:10:25 AM PST · by Red Badger · 29 replies
    www.theburningplatform.com ^ | November 30, 2022 | Staff
    Story at-a-glance: * A carnivore or meat-only diet can be uniquely beneficial for some people, especially those struggling with autoimmune diseases, Crohn’s disease, ulcerative colitis, chronic pain and mental health disorders * It can also be used as a detox strategy for three to 12 months * One of the primary benefits of a carnivore diet — as long as you focus on red meat and limit chicken and pork — is that it’s a really low in omega-6 fat, which is the most harmful type of fat and a primary driver of chronic disease * You’re also removing most...
  • Scientists Warn That Triclosan – Found in Toothpaste and Toys – Triggers Harm to the Gut

    01/11/2022 10:23:31 AM PST · by Red Badger · 22 replies
    https://scitechdaily.com ^ | January 11, 2022 | By UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Research by the University of North Carolina at Chapel Hill and an international team traces the toxic impact of a common consumer product on the gut microbiome and induces colitis. A new study conducted in mice demonstrates precisely how triclosan, an antimicrobial found in toothpaste, toys, and thousands of other products, can trigger gut inflammation. An international team of researchers led by the University of North Carolina at Chapel Hill, the University of Massachusetts Amherst and Hong Kong Baptist University identified the bacteria, and even specific enzymes, that trigger triclosan’s harmful effects. Moreover, studies in mice suggest these bacterial enzymes...
  • Pills made from poop cure serious gut infections

    10/10/2013 2:58:34 PM PDT · by neverdem · 19 replies
    Associated Press ^ | Oct 04, 2013 | Marilynn Marchione
    Hold your nose and don't spit out your coffee: Doctors have found a way to put healthy people's poop into pills that can cure serious gut infections — a less yucky way to do "fecal transplants." Canadian researchers tried this on 27 patients and cured them all after strong antibiotics failed to help. It's a gross topic but a serious problem. Half a million Americans get Clostridium difficile, or C-diff, infections each year, and about 14,000 die. The germ causes nausea, cramping and diarrhea so bad it is often disabling. A very potent and pricey antibiotic can kill C-diff but...
  • FDA grapples with oversight of fecal transplants

    07/13/2014 7:38:56 PM PDT · by Olog-hai · 37 replies
    Associated Press ^ | Jun. 26, 2014 1:20 PM EDT | Matthew Perrone
    Imagine a low-cost treatment for a life-threatening infection that could cure up to 90 percent of patients with minimal side effects, often in a few days. It may sound like a miracle drug, but this cutting-edge treatment is profoundly simple—though somewhat icky: take the stool of healthy patients to cure those with hard-to-treat intestinal infections. A small but growing number of physicians have begun using these so-called fecal transplants to treat Clostridium difficile, commonly referred to as C-diff, a bacterial infection that causes nausea, cramping and diarrhea. The germ afflicts a half-million Americans annually and kills about 15,000 of them....
  • 'Hell's Kitchen' contestant Jessica Vogel dead at 34

    08/01/2018 4:38:08 PM PDT · by BenLurkin · 33 replies
    Vogel's fiance, John Michael Keyser, told NorthJersey.com that the chef's "heart gave out" while receiving treatment for colitis at a local hospital. Colitis is a disease which causes inflammation in the digestive tract. Vogel studied culinary arts at Johnson & Wales. She auditioned for the Gordon Ramsay-hosted show while working at a creperie and bakery in California, NorthJersey.com reported. She also worked as a pastry chef for chef Christine Nunn at Grange in Westwood. She recently worked as the executive chef of Black Rebel Burger in Hackensack, N.J. before it shut down last year. "When she set her mind on...
  • Art Bell in the Hospital again..(for Coast to Coast AM listeners)

    07/02/2016 12:44:40 AM PDT · by lee martell · 27 replies
    July 2 2016 | Lee Martell
    George Noory made a brief mention that Art Bell has been in and out of the hospital here lately. He is back in now for problems with COPD (shortness of breath) Colitis and possible pneumonia. I can't get Art on my terrestrial radio, and am not yet in the habit of using my computer to get radio. So, I hadn't given Art any thought in quite a few months. I was saddened to hear that he's been feeling poorly for the last few months. Art is not quite sure when he'll be back on the air. He does have a...
  • Bacterial molecules may prevent inflammatory bowel disease

    07/13/2013 5:53:23 PM PDT · by neverdem · 34 replies
    Science News ^ | July 9, 2013 | Jessica Shugart
    Common compounds produced by gut microbes quench colitis in mice Common molecules made by bacteria in the gut may act as chill pills for the immune system. Molecules secreted by intestinal bacteria work to prevent misplaced immune attacks in inflammatory bowel diseases like colitis, a new study finds. “It is a huge advance,” says Sarkis Mazmanian of Caltech. “This opens up the notion that a very easy and potentially very safe therapy for inflammatory bowel disease could exist.” Decades of research have hinted that microbes play a role in immune-related diseases such as obesity, allergy, inflammatory bowel disease and colon...
  • DNA from common stomach bacteria minimizes effects of colitis, U-M study says (yes, H. pylori)

    05/05/2011 3:12:59 PM PDT · by decimon · 3 replies
    Administration of Helicobacter pylori DNA reduces symptoms, new research reveals pathway for future treatmentsANN ARBOR, Mich. — DNA from Helicobacter pylori, a common stomach bacteria, minimizes the effects of colitis in mice, according to a new study by University of Michigan Medical School scientists. The study published in Gut this month was performed by a team of investigators assembled by senior author John Y. Kao, M.D. of the University of Michigan's Division of Gastroenterology and assistant professor in U-M's Department of Internal Medicine. The findings indicate that DNA from H. pylori significantly ameliorates the severity of colitis, say lead authors...
  • Sugar hit triggers bug's drug slug - An engineered bacterium can deliver a therapeutic...

    08/22/2009 1:41:45 PM PDT · by neverdem · 7 replies · 936+ views
    Nature News ^ | 21 August 2009 | Mico Tatalovic
    An engineered bacterium can deliver a therapeutic protein straight to the gut when fed with xylan.Could genetically-engineered bacteria help to banish gastrointestinal woes?Punchstock A gut-dwelling bacterium has been genetically engineered to deliver a dose of therapeutic protein on demand.Protein production in the engineered bacterium is switched on only when its host eats the complex sugar xylan. Tests on mice that had colonies of the bacteria in their guts showed that the expressed protein can successfully treat an inflammatory bowel disease called colitis.The research, to be published in the journal Gut1, has potential as an alternative method for delivering drugs to...