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Researchers have identified a potential dietary supplement that may improve recovery following acute kidney injury (AKI). The finding comes from a long-running research program investigating how cells take up a specialized omega-3 lipid called LPC-DHA. A major public health concern, AKI has a mortality rate of 20 to 50%. One of the main causes of AKI is ischemic reperfusion injury, which occurs when the kidney's blood supply is restored after a period of restricted blood flow and poor oxygen delivery due to illness, injury or surgical intervention. In particular, it damages a crucial part of the kidney called the S3...

Experts are speculating that climate change and other factors are driving the increase in kidney stone cases among children and teens. Experts told NBC News that just three decades ago, kidney stones were largely a disease that affected middle-aged White men, but they now increasingly affect children and teens, especially in the summer."My research group has focused on the relationship between temperature and kidney stone presentations for a decade," Dr. Gregory Tasian, a pediatric urologist at Children’s Hospital of Philadelphia, told Fox News Digital when asked about climate change and kidney stones."The summary is that hot days increase the frequency...

Over the course of the last several decades, the rate of obesity has progressively increased and is now one of the leading causes of death worldwide—650 million adults are classified as obese. The World Health Organization (WHO) defines obesity as the accumulation of excessive fat in the body creating risks for a healthy life. The main causes: changing diets and lifestyles. But what are bad eating habits doing to our blood vessels? A research team led investigated how obesity impacts blood vessels' structure at a molecular level. The team's research illustrates that metabolic disease affects blood vessels in different organs...

Cisplatin is a chemotherapy indicated to fight tumors in many types of cancer. However, it does have major side effects—especially kidney toxicity, that can lead to acute kidney failure. In addition, patients treated with cisplatin also often report high levels of neuropathic pain. Scientists have identified a drug that could be a game changer for patients. Istradefylline, which is already approved for Parkinson's disease, could not only reduce the harmful effects of cisplatin but also improve its anti-tumor properties. These findings will now need to be confirmed in a clinical trial. Cisplatin is a chemotherapy used to treat several types...

Glomerular filtration rate (GFR) is the best overall index of kidney function. Normal GFR varies according to age, sex, and body size, and declines with age. The National Kidney Foundation recommends using the CKD-EPI Creatinine Equation (2021) to estimate GFR. NKF and the American Society of Nephrology have convened a Task Force to focus on the use of race to estimate GFR.

Anyone who is taking a diuretic and a renin-angiotensin system (RSA) inhibitor for high blood pressure should be cautious about also taking ibuprofen, according to new research. Diuretics and RSA inhibitors are commonly prescribed together for people with hypertension and are available under various pharmaceutical brand names. Painkillers such as ibuprofen are available over-the-counter in most pharmacies and stores in popular brands. Researchers used computer-simulated drug trials to model the interactions of the three drugs and the impact on the kidney. They found that in people with certain medical profiles, the combination can cause acute kidney injury, which in some...

Herat (Afghanistan) (AFP) – Jobless, debt ridden, and struggling to feed his children, Nooruddin felt he had no choice but to sell a kidney -- one of a growing number of Afghans willing to sacrifice an organ to save their families. The practice has become so widespread in the western city of Herat that a nearby settlement is bleakly nicknamed "one kidney village". "I had to do it for the sake of my children," Nooruddin told AFP in the city, close to the border with Iran. "I didn't have any other option." Afghanistan has been plunged into financial crisis following...

UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human. The study was designed and conducted to meet standards directly comparable to those that would apply to a Phase I clinical trial and mirrored — as much as possible — every step of a conventional transplant between humans. The University of Alabama at Birmingham Marnix E. Heersink School of Medicine announces today the first peer-reviewed research outlining the successful transplant of genetically modified, clinical-grade pig kidneys into a brain-dead human individual, replacing the recipient’s native kidneys. These positive results demonstrate how xenotransplantation could address the worldwide organ shortage...

(StudyFinds.org) – Although studies show COVID-19 is capable of infecting a patient’s kidneys, the virus’s exact impact on the organs has been unclear – until now. A team of German and Dutch scientists report COVID-19 causes direct cellular damage within the kidneys, contributing to tissue scarring. Conducted at the RWTH Uniklinik Aachen in Germany and the Radboud University Medical Center in the Netherlands, study authors assessed and compared kidney tissues among COVID-19 ICU patients, other patients in the hospital for a non-COVID-related lung issue, and a group of healthy people. Results show kidney tissue from the COVID-19 patients showed much...

An all Indiana University School of Medicine team found that chlorthalidone was effective in lowering blood pressure in individuals with advanced kidney disease. "Kidneys are key regulators of blood pressure. When an individual has chronic kidney disease, the kidneys are unable to control blood pressure," said Agarwal. "If a person suffers from chronic kidney disease and high blood pressure, it is more likely their kidney disease will advance even further and lead to other health issues such as heart failure." Chlorthalidone was approved by the FDA in 1960 for treatment of high blood pressure or hypertension. However, it was largely...

..... For pro-life Americans, however, there remains the serious ethical concern over the use of cells harvested from aborted fetuses in testing and developing the various coronavirus vaccines. How is one to make a moral judgment in weighing the cost of taking one of these two vaccines against the cost of waiting for the release of others in which fetal cell lines played no role at all? Neither of the two pro-life advocates I spoke with on the topic — Dr. Joseph Meaney, president of the National Catholic Bioethics Center, or Dr. Tara Sander Lee, a senior fellow at the...

A federal judge has issued an order demanding that a group of pro-life activists who were behind a series of undercover videos taken at Planned Parenthood facilities and abortion conferences are liable for more than $1.2 million in damages. U.S. District Court Judge William Orrick of the Northern District of California released an order Wednesday against individuals connected to the Center for Medical Progress. At issue was an Unfair Competition Law claim brought by Planned Parenthood and the plaintiffs California Business & Professions Code. Orrick ruled in favor of the claim, citing a jury verdict from last November that found...

Exposing Shocking Horrors Inside Sujiatun Concentration Camp By Ji Da Epoch Times Staff Mar 11, 2006 A reporter from China who worked for a Japanese television news agency and specialized in Chinese news recently escaped to the United States after being wanted in China for reporting on controversial issues. (The Epoch Times) High-res image (1200 x 900 px, 72 dpi) [ Warning: graphic photos below ] Falun Gong Practitioners a Cheap Source of Black Market Organs In recent years, international organ buying and selling markets have had extreme shortages. As the world's most populous country with the death penalty, China...

“It makes no difference if they are criminals, flesh peddlers, and smut dealers that are exploiting American and Ecuadorian people for profit. For Clinton, if you have enough money, anything goes. This is just another reason why her brand of corruption must not be allowed into the White House.”

A Phoenix woman reportedly sent a man she met on a dating website more than 159,000 texts – including one stating that she wanted to turn his kidneys into sushi. According to police documents obtained by the Arizona Republic, Jacqueline Ades allegedly sent the man the messages over the span of nearly 10 months. She had originally been accused of sending him more than 65,000 text messages but the number was reportedly more than double that. The arrest records listed the woman as “showing signs of mental illness,” the newspaper reported. Ades reportedly met the victim, a Paradise Valley man...

Life will be great again when I pass this damn thing. Right now, it's giving me a break. Started this past late Friday morning while driving. Ever since then, it's been off and on pain on a level of 7 out of 10. Early this morning was an ordeal as the pain started just after midnight and lasted until about 3:30am. I had to take the day off work. Been drinking boatloads of water since Friday. Someone said drink fresh lemonade or lemon juice. Thoughts? BTW, this is my 3rd bout with these things so not my first rodeo. First...

Dr. Thamar Eilam Gindin, and expert on ancient Persia and modern Iran, spoke today (Tuesday) with Anat Davidov on Radio 103FM and referred to the sanctions imposed by US President Donald Trump on Iran yesterday. "I found a heartbreaking site, in which there are dozens of people with phone numbers offering to sell their kidney," said Dr. Elam Gindin. Iran's economy was teetering even before the sanctions were re-imposed. Last week, the Iranian rial plunged to a record low of less than 1,000 to the American dollar. "What is going to happen today are restrictions on foreign currency trading. It...

Full Title: O'Keefe Catches Antifa 'Fight Instructors' Teaching Activists How To Inflict Pain on Their Targets A new undercover video from James O'Keefe's Project Veritas features Antifa “fight instructors” teaching activists how to incapacitate political enemies by violently attacking them. "If you get a good liver or kidney shot, it's pretty much crippling them," the Antifa instructor said. "They're going to be pretty much doubled over and in a lot of pain." The instructor also recommended breaking one of the floating ribs to cause maximum pain in a victim. "It's hard to move after that -- to catch a breath,"...

Doctors have long known that patients with diabetes are at risk for kidney disease. But the new study shows that patients could be suffering undiagnosed kidney damage even before they are aware that they have diabetes. ...the researchers found that more than 30 percent of diabetic veterans had prior CKD signs. The results appeared in the Feb. 9, 2018, issue of the journal PLoS One. About 10 percent of the U.S. population -- around 20 million people -- have CKD. Diabetes is the leading cause of CKD and end-stage renal disease. One-third of adults with diabetes have CKD. Other conditions...

A daily dose of sodium bicarbonate—baking soda, already used for baking, cleaning, acid indigestion, sunburn, and more—slows the decline of kidney function in some patients with advanced chronic kidney disease (CKD), reports an upcoming study in the Journal of the American Society of Nephrology (JASN). "This cheap and simple strategy also improves patients' nutritional status, and has the potential of translating into significant economic, quality of life, and clinical outcome benefits," comments Magdi Yaqoob, MD (Royal London Hospital). The study included 134 patients with advanced CKD and low bicarbonate levels, also called metabolic acidosis. One group received a small daily...