A friend of mine worked for a short time in HVAC. The older guys reminder just carrying R-22 in the vans, now they carry R448, R407, R134a, R410a, R-1234yf and R-1234ze, etc. based on the use. What I was told was R-22 would work in anything except automotive, from massive supermarket systems either medium temp (dairy, produce, etc) or low temp (frozen, beer coolers) now what works in medium temp wont work in low temp, etc.
I think back in the good old days, when car air conditioners blew really cold, they used R-22
The newer “more environmentally friendly” ™ refrigerants are highly compressed unlike R22 which causes many more leaks and the latest stuff is highly flammable. Talk about reinventing the wheel and creating problems where there were none.