The big lie, smallpox was weaponized in 1977 if not before. Big Brother is not your friend. Sleep tight, don't let the politicians bite.
Even if the cultures still alive (freeze dried) in the U.S. and Russia had been destroyed, someone could have resurrected it from the genetic code which was sequenced around 1990.
There will be plagues at the end of the world, and the AntiChrist. When it comes to Big Brother, you ain't seen nothin' yet, and I hope you never do. Hope you're in the Rapture or die painlessly in bed at an old age.