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Scientists Zeroing in on Gene for Ear Wax
Reuters Health via Yahoo ^ | 6-7-02 | Anon Reuters Health Stringer

Posted on 06/07/2002 1:49:43 PM PDT by Pharmboy

NEW YORK (Reuters Health) - While studying Japanese families with a rare movement disorder, researchers have discovered a region of DNA that may contain the gene for ear wax.

A discovery of the ear wax gene could help shed light on the function of apocrine glands, fluid-secreting cells found throughout the body, and may even have implications for breast cancer. Some studies have found the women with a certain type of ear wax are at greater risk of developing breast cancer than those with another type.

Ear wax, or cerumen as it is know scientifically, is produced by hair follicles and glands that line the ear canal and protects the ear by trapping dust, microorganisms and foreign particles, and prevents them from entering and damaging the ear. There are two types of ear wax--"wet" and "dry." Most whites and blacks in the US have the wet type, which is more brown, sticky and wet, while Asians and Native Americans tend to produce the dry type, that tends to be brittle and tan or gray.

According to a report in the June 8th issue of the medical journal The Lancet, Dr. Hiroaki Tomita of Nagasaki University School of Medicine in Japan and colleagues got a stroke of luck when they came across a Japanese woman with a neurological condition who also had wet ear wax, an unusual type for a person of Asian descent.

Six other members of the woman's family also had the neurological condition--known as paroxysmal kinesigenic choreoathetosis--as well as wet ear wax. In paroxysmal kinesigenic choreoathetosis, a patient experiences uncontrollable twisting movements of the limbs in response to sudden voluntary motion.

The researchers then obtained DNA samples from eight Japanese families, 92 people in all, and searched a region of chromosome 16, where the gene for the neurological disorder was known to be located. They looked at 11 different segments of the gene, and narrowed down the location for the gene to one particular portion.

"Identification of the ear wax (gene) could contribute to further (human development) studies and to physiological and pathological understanding of the apocrine-gland development," Tomita and colleagues conclude. Tomita is currently at the University of California-Irvine.

SOURCE: The Lancet 2002;359:2000-2002.


TOPICS: Culture/Society
KEYWORDS: breastcancer; earwax; ethnicdifferences
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Ear wax may have a connection to breast cancer...a good argument here for basic research: you never know what you'll find.
1 posted on 06/07/2002 1:49:43 PM PDT by Pharmboy
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To: Pharmboy
Forget that! Where's the gene to turn off ear hair?
2 posted on 06/07/2002 1:52:47 PM PDT by toenail
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To: toenail
I never had ear hair until I turned 40...maybe ear hair that grows later on in life is associated with intelligence? Nah.
3 posted on 06/07/2002 1:55:52 PM PDT by Pharmboy
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To: toenail
Hair never falls out, it just gets confused. Just ask Henry Waxman.
4 posted on 06/07/2002 1:56:37 PM PDT by gov_bean_ counter
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To: toenail
"Where's the gene to turn off ear hair?"

Unfortunately, it's connected to the gene for... ahem... manly hydraulic function.

5 posted on 06/07/2002 1:59:43 PM PDT by Harrison Bergeron
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To: Pharmboy
Well, if they can hook this up with a yeast plasmid or two, the worldwide shortage of earwax is over, baby...
6 posted on 06/07/2002 2:00:37 PM PDT by Billthedrill
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To: Harrison Bergeron
LOL!! Are you a fan of The Greaseman?
7 posted on 06/07/2002 2:01:19 PM PDT by tracer
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To: Pharmboy
Treatment for the ass pimple cannot be far behind.
8 posted on 06/07/2002 2:01:41 PM PDT by Williams
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To: Billthedrill

Scientists Zeroing in on Gene for Ear Wax...
It's about time!!!!


9 posted on 06/07/2002 2:01:54 PM PDT by vannrox
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To: Williams
At that point Dasshole is "dead meat".
10 posted on 06/07/2002 2:02:28 PM PDT by gov_bean_ counter
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To: toenail
Forget that! Where's the gene to turn off ear hair?

Nose hair comes first!

11 posted on 06/07/2002 2:04:18 PM PDT by N. Theknow
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To: Pharmboy;physicist;radioastronomer
a good argument here for basic research: you never know what you'll find.

Hear, hear!

12 posted on 06/07/2002 2:08:12 PM PDT by Chemist_Geek
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To: vannrox
Our long national nightmare is over...(sniff)
13 posted on 06/07/2002 2:09:12 PM PDT by Pharmboy
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To: Pharmboy
What?
14 posted on 06/07/2002 2:10:29 PM PDT by Arcturus
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To: Arcturus
Well, if someone didn't notice the fact that the Japanese with this rare condition had unexpected ear wax properties, then the gene would not be located. Other associations could follow, and this might turn out to be a worthwhile pursuit.

Then again, it could all amount to nuthin' at all...

15 posted on 06/07/2002 2:13:58 PM PDT by Pharmboy
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To: Pharmboy
Hah - ain't nuthin' - now THIS is a great Japanese technical triumph:

Spray here

16 posted on 06/07/2002 2:23:20 PM PDT by Billthedrill
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To: Pharmboy
I'm turning 30 tomorrow. I should ask for some ear hair clippers for my birthday.
17 posted on 06/07/2002 2:28:56 PM PDT by Big Guy and Rusty 99
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To: Chemist_Geek
shouldn't that be "ear, ear?"
18 posted on 06/07/2002 2:30:03 PM PDT by Big Guy and Rusty 99
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To: Big Guy and Rusty 99
shouldn't that be "ear, ear?"

The correct pronunciation would be "'ear, 'ear"...

19 posted on 06/07/2002 2:42:22 PM PDT by okie01
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To: Harrison Bergeron
"Where's the gene to turn off ear hair?" Unfortunately, it's connected to the gene for... ahem... manly hydraulic function.
Um ... er ... ah ... actually ... well ... um ... my "friend" has noticed that as the quantity of his ear hair has increased, the quantity of his manly hydraulic function has decreased.
20 posted on 06/07/2002 2:50:34 PM PDT by Prolix
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