http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/P/Polymorphisms.html#GeneticDrift
Condorman, I will take any credit you are willing to give. I am glad to hear that you do want to move forward with a mathematical model. The mouse thing was meant to be a tight analogy with our discussion of evolution vs. intellignet design. I was only trying to show that it is not necessary to reproduce the Creator in a laboratory in order to infer that non-random forces had been at work.
Since you have said that I misinterpreted and you DO think this thought experiment of ours has some value, it does not matter about the analogy. (Also as an aside, I thought the very same thing. Where could such critters prosper? Perhaps in the block crawl space under my house, where they could attract bugs to eat and no large predators can enter (well, maybe a snake.))
So I am being very generous here- whenever the numbers are in doubt, I am conceding the numbers to you two. Whenever there is doubt about how much of the genome is functional (i.e. is 'junk DNA really 'junk'', I think most of it is not, you think it is) I am conceding it to you. I am bending every step of the way and using your own numbers at every point.
So here it is : we are agreed that the minimum differences in mutations would require one fixation in the population's overall genome every three months, with one fixation in the coding regions every 8 years? Yea or Nay?
That works for me. In fact, since the whole "problem" is how to account for whatever differences there are, it doesn't really matter to me about the coding genes. So for me the supposed problem is in accounting for all the differences. (See? I'm generous too! :-)
If that's what it works out to be then sure.
The next step, I suppose, is to identify possible mechanisms for the change.