I just wrote a long post about how I wouldn’t worry about over penetration. OK. You use a .270 for home defense? Now it is time to worry about over penetration. Any misses now have a substantial risk of danger. You hope it splatters on something, but those long bullets with their relatively high ballistic coefficient launched at 3,000 feet per second.
Yes, over pentration. I would never use a high powered rifle for home defense in a suburb. Out in the stick with a mile between neighbors, sure. In the suburbs? Absolutely no way. I think any high powered rifle cartridge is a bad choice to use in the suburbs. Not even the .223.