When we're born, we're either XY or XX chromosomes. When we die, we're either XY or XX chromosomes. End of story.
Also, Johns Hopkins Psychiatrist: Transgender is Mental Disorder;' Sex Change Biologically Impossible
The good news is, "The pro-transgender advocates do not want to know, said McHugh, that studies show between 70% and 80% of children who express transgender feelings spontaneously lose those feelings over time."
That's nearly the End of Story, but not quite. There are rare cases of men with XXY, XXXY, or even XXXXY.
Bruce /Caitlyn Jenner sure as heck doesn't have an extra X chromosome. No one winning a men's olympic decathlon gold could possibly.