At least "on paper" I really, really doubt it.
If no other team is even close, why will they necessarily lose a game?
“USC will lose a game.”
If I am a coach of a second tier football program and I have SC on my schedule, I know that a win over SC will make my season and my career, even if my team ends up having a .500 season. So I will be game planning against SC year round and I will motivate and prepare my players for this game like no other. Just remember Cal coach Tedford in 2003...