Sugar and HFCS react differently in the Liver. HFCS strains the Liver much worse than Cane Sugar.
And that's exactly part of the problem. HFCS has to pass through the liver twice to digest it. I always try to avoid HFCS but it's ubiquitous. On the other hand, while HFCS is bad for you, I bet people ingesting this much sugar are already fat with bad lipid profiles. However, no doubt HFCS exacerbates the problem and should be avoided.
How is that possible when both products are comprised of the same two chemicals? Is fructose and glucose from hydrolyzed sucrose chemically different from glucose and fructose in HFCS?