About 75 miles north of Tokyo.
We know the Romans had trade with Vietnam (or at least, a large horde of their coins was found there). Either they—or intermediary merchants—apparently also transported their goods as far as Japan.
(The “Global Economy” is just a fancy term for what has always existed, imho.)
No, it's about 20 miles east of Osaka and 30 miles south of Kyoto; it was the first capital of imperial Japan, to be succeeded by Kyoto.