I have never found semi-autos as reliable as wheel guns because eventually, a semi- will FTF. But, in a defensive scenario, you wouldn’t have already snapped off 150 rounds. The debate will rage forever over “six for sure” vs. “semi-auto-jammers.” The best bet with either is to make the first shot count as best you can - center mass. And, that means practice, practice, practice.
Yep, I wish I would have shot a Ruger .380 before I bought it. My husband likes it so maybe I will give it to him.