No.
It depends on your situation. If you are just a wage earner and have at least paid as much tax as you owed last year, there is no penalty. Also, if you are within a certain percentage (don’t know the exact number) you are fine.
If you have income from other sources and pay estimated taxes, it gets more complicated and there are other criteria. I do a running calculation throughout the year and usually estimate it very close. But, there are some tax preference items like qualified dividends that I don’t try to account for, because I don’t know the exact amount. So, I treat all dividends as ordinary income.
I end up getting a small to medium—sized refund every year, but simply reduce my first estimated tax payment on 4/15 by that amount.