Do you pay for your programs?
You can download the free versions of these programs, manually update them, and then do scans, you should do that with malwarebytes.
I also prefer to put all of my security programs on the deepest, fullest, scan, when I do scans.
What browser do you use?
I pay for eset, and use the free version of super antispyware. I update it every morning and run for spyware, it just takes a few minutes.
I’m on internet explorer, windows 8.1