“Foreign entanglements” hardly includes secession, but I got that from the movies anyway.
No but there are explicit warnings directed at the Democrats who were toying with the idea of splitting the Union and allying with France. I think the term he used was “...cunning, ambitious and unprincipled men” inflaming sectionalism as a danger.
The no foreign entanglements was also particularly directed at those wishing to ally with France.