Those rounds are definitely geared for hunting. Not practical for taking down two legged creatures.
Depends on the round you choose. This one from Doubletap:
http://www.doubletapammo.net/index.php?route=product/product&path=126_134&product_id=589
A perfect match for someone needing a high speed, low penetrating option for home defense or CCW. This loads offers 11.5” of penetration with .7” of expansion and EXTREME fragmentation throughout the wound channel. One of the most desturctive rounds on target produced to date in the 10mm.
Caliber: 10mm
Bullet: 135gr. Sierra Jacketed Hollow Point.
Ballistics: 1600fps / 767 ft.lbs. - Glock 20
Or you can buy ammo loaded just above 40 S&W. My gun came with 3 spring weights. I only shoot it with the heavy spring since black bears are my main threat right now.
By “off the beaten path” I meant out in the field like hunting, etc.