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To: Qiviut

Plz explain why cholecalciferol is also the ingredient used in D-Con rat poison? You couldn’t pay me to take that seco-steroid hormone D. It’s not even a real vitamin


13 posted on 04/07/2021 5:38:08 AM PDT by SaintDismas
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To: SaintDismas

You could just go to Wikipedia, I suppose, for what it’s worth.

https://en.wikipedia.org/wiki/Cholecalciferol

Rodenticide​[edit]

Rodents are somewhat more susceptible to high doses than other species, and cholecalciferol has been used in poison bait for the control of these pests.[40][14]

The mechanism of high dose cholecalciferol is that it can produce “hypercalcemia, which results in systemic calcification of soft tissue, leading to kidney failure, cardiac abnormalities, hypertension, CNS depression, and GI upset. Signs generally develop within 18-36 hr of ingestion and can include depression, loss of appetite, polyuria, and polydipsia.”[13] High-dose cholecalciferol will tend to rapidly accumulate in adipose tissue yet release more slowly[41] which will tend to delay time of death for several days from the time that high-dose bait is introduced.[40]

In New Zealand, possums have become a significant pest animal. For possum control, cholecalciferol has been used as the active ingredient in lethal baits.[42] The LD50 is 16.8 mg/kg, but only 9.8 mg/kg if calcium carbonate is added to the bait.[43][44] Kidneys and heart are target organs.[45]

It has been claimed that the compound is less toxic to non-target species. However, in practice it has been found that use of cholecalciferol in rodenticides represents a significant hazard to other animals, such as dogs and cats.[13]


15 posted on 04/07/2021 6:29:32 AM PDT by Larry Lucido (Donate! Don't just post clickbait!)
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