Posted on 06/10/2021 9:04:17 PM PDT by ConservativeMind
A British man who rejected the standard of care to treat his brain cancer has lived with the typically fatal glioblastoma tumor growing very slowly after adopting a ketogenic diet, providing a case study that researchers say reflects the benefits of using the body's own metabolism to fight this particularly aggressive cancer instead of chemo and radiation therapy.
Published recently in the journal Frontiers in Nutrition, the report is the first evaluation of the use of ketogenic metabolic therapy (KMT) without chemo or radiation interventions, on a patient diagnosed with IDH1-mutant glioblastoma (GBM). Ketogenic therapy is a non-toxic nutritional approach, viewed as complementary or alternative, that uses a low-carbohydrate, high-fat diet to manage a range of cancers, including glioblastoma.
In this particular case, the patient's tumor contained a mutation, known as the IDH1. This mutation is acquired by chance and is known to improve overall survival.
"In light of continued slow progression of the residual tumor, the patient intensified his KMT starting in October, 2018 with inclusion of mindfulness techniques to reduce stress. While Magnetic Resonance Imaging (MRI) shows slow interval tumor progression, the patient remains alive with a good quality of life at the time of this report." He is now at 82 months from original diagnosis.
"We were surprised to discover that KMT could work synergistically with the IDH1 mutation to simultaneously target the two major metabolic pathways needed to drive the growth of GBM," said Seyfried. "Glucose drives the glycolysis pathway, while glutamine drives the glutaminolysis pathway."
He added: "No tumor, including GBM, can survive without glucose and glutamine. Our study has identified a novel mechanism by which an acquired somatic mutation acts synergistically with a low-carbohydrate, high-fat diet to provide long-term management of a deadly brain tumor."
(Excerpt) Read more at medicalxpress.com ...
Wish I thought you were trustworthy but the South Beach diet works...
ANS it was written by a Miami Beach heart doctor who had great results with his patients, esp. those overweight and type II diabetes.
I will add I’ve read more than a few accounts of doctors/experts blaming this diet for causing heart attacks and to that I say horse hockey. Maybe folks with a bad ticker should not be on this diet but it’s ridiculous to blame getting off of carbs and sugars and then claiming this diet causes the very problems that are likely already there from poor diet and a complete lack of exercise.
And I read some of your posting history, experimental covid vaccines are not the answer when anyone can boost their immune system with proper diet and exercise. These ‘vaccines’ are crippling and killing many who trust the ‘experts’ - CDC, NIH, Fauci etc.
The problem with relying solely on a keto diet is the threat of gout. Substituting too much meat for carbs can be dangerous. Gout can result in amputations and worse, far worse.
That said, cancer is not the genetic disease most oncologists try and tell us. Cancer is a disease of cellular metabolism. mRNA receive energy from mitochondria. mRNA use the energy to communicate genetic requirements for performing specific tasks. Alcohol, fructose, glutamates and aspartates cause mitochondrial DNA to mutate so that they turn out energy at wavelengths which are unusable. The process also causes the production of “junk” in the cytosol. Exercise can help clear out the junk, but it has trouble reversing the fact that the shortage of cellular energy tells cellular epigenes to start creating tissue instead of energy.
I’m 70 and the wife is 68. She started the Keto lifestyle 18 months ago. I do all the cooking so it was a challenge for me. She has lost 50 lbs. And has had issues with breathing that they couldn’t diagnose. This has been alleviated. She just left this morning on a Southern Baptist training mission. And I am really proud of her. Myself I resisted KETO and always fixed a carb side dish for me. Two months ago I said this is stupid and cut out the carbs. My blood pressure before was 148 over 97 (not good). Since I started KETO my weight has dropped from 218 to 197 (first time I’ve been below 200 in 30 years). My blood pressure has dropped to 117 over 72. And I’m feeling great. KETO may not be for all, but it is sure is working for us.
In left field and badly presumptive, you are...
Good luck with that. ANY ‘diet’ is a step in the right direction from the alternative, but they are ALL dangerously myopic. It’s easy to discern the myopia; your comment is characteristic.
I know: I’ve met people suffering the effects, having tried all and frustrated that no one can help them, so angry/frustrated that they get angry at me because there is no quick fix.
And deny it all you want, but SB is NOT panacea, otherwise it would have worked for me & others...plus the fact that EVERYONE would be on it as well.
I’m not going to address your other comment on ‘vaccines’; you have a reading comprehension problem.
Interesting. Reinforces my point as well.
Nope -you are confusing high protein diets, those are tough on the kidneys. But its tough to do a ketogenic diet and avoid over consumption of protein.
As far as I know, gout is cured by taking baking soda water... it neutralizes the uric acids. Works for my Dad.
Fibers are non-caloric, but are still considered a form of carbohydrate.
Fibers are “allowable” carbs. You can have as much of these as you'd want.
Another generally allowable carb is what is known as a “sugar alcohol.” These are in some natural sugar substitutes such as erythritol, allulose, xylitol and others, but are not in pure monk fruit stevia. Pure manufactured sugar substitutes like Splenda, saccharine, NutraSweet, and others don't have sugar alcohols, either, but strangely can cause spikes in insulin in the body, which can make your body partially behave like you are ingesting carbs, even though you aren't.
Many sugar substitutes, either the natural or manufactured ones, have a binder that is a carbohydrate. The big bags of Splenda, for instance, have Splenda molecules attached to maltodextrin, a starch. Maltodextrin is 100 on the Glycemic Index, while white sugar is in the high 70s, meaning maltodextrin is the same effective thing in our bodies as the blood glucose we make to stay alive. However, the fluffy maltodextrin in such bags of sugar substitutes are still so minimal in calories that such sugar substitutes can still keep one in the parameters of their super low carb diet, with limitations.
Technically, a keto diet is a super low carb diet in which people have fewer than 30 fully digestible grams of normal carbs a day. This forces one into ketosis, which makes your body burn fat over carbs. People who are not severely diabetic or having bad problems with their liver can make all the carbs their body needs through their liver (this happens to some extent to all humans every day, naturally, as we turn fat stores back into blood glucose for energy).
People wanting to prove their body is using fat can buy “keto strips” and test their urine at home.
Generally, when a person's body is changing over to a keto diet, within two to three days, you will likely become quite sleepy, followed by becoming energetic again. This is a natural feeling as your body's cells finally switch to the fat backup system they have.
When your carbs come only from fat and and some protein (yes, your body, through your liver, can also turn protein into blood sugar), you will never get more blood sugar than you need and never have more insulin than it needs.
If you have unusual health conditions, it is wise to talk to a doctor before trying such a diet.
I hope this helps. I will say your appetite goes away and you naturally are much less hungry than on a normal diet.
I have said a similar thing to my wife.
God has assured so many process exist in nature. These processes can be found and used to supplement or supplant problems humans have.
Correct, this specifically works for him because of a mutation in his cancer.
A more normal carb diet is fine if you can burn off the converted carbs through work or exercise in a timely manner or if you ate low Glycemic Index/Load carbs, which cause a much lower spike in blood glucose and insulin response. However, all carbs ingested will make one’s blood glucose and insulin go above the baseline a low carb diet creates. For some people, those spikes are a step too far, simply because of their bodies under the constraints they’ve sadly allowed, and even complex carb spikes further their current dysfunction.
Dr. Atkins’s expectation under the final phase of the Atkins diet was people ingesting no more than 100 grams of carbs, preferably all complex, for life. My guess is that you would find that a healthy approach, am I right?
I will say my wife and I eat seaweed and enjoy it and we will occasionally have natto with mustard (a strange, yet fun food).
I will look through your reference. Thank you!
Well I’ll apologize for mis-reading your stance on vaccines but I was not defending any diet as a panacea simply one that does help. I use many natural & OTC stuff for strengthening my immune system, but I see no reason to believe a keto diet would weaken anyone’s immune system either.
Also I was on keto for over a year before I started to lose significant weight. I stayed with it bc I did still lose inches on my belly fat and felt much more energetic and mobile in the 1st year. After almost 3 years now, dropped over 60lbs so bottom line it does help but maybe not all are persistent or disciplined enough to follow it. I do miss the sugars and carbs except for the fact they were killing me every day in every way.
Keto is not high protein, in fact one must typically moderate protein intake on a ketogenic diet.
**As far as I know, gout is cured by taking baking soda water... it neutralizes the uric acids.**
Lots of exercise can mitigate gout because excess uric acid is not primarily a pH problem. It is a metabolic problem. Uric acid is the final product of ATP oxidation of food. It goes ATP, ADP, AMP and uric acid. That said, the chemical manifestation of oxidation-reduction reactions is pH.
However, the body uses stringent means to control blood and digestive pH to a narrow band. Look up aldosterone. You can’t dissolve excess uric acid crystals with a neutral blood pH alone.
I believe that a sedentary COVID lifestyle combined with my keto diet brought on my gout. The liver sees a lack of glucose and assumes that a person is fat adapted so it does not convert animal protein into glucose. Instead, the liver oxidizes the protein into uric acid ...hyper-uricimia.
I was able to cut way back on meat protein, and add some carbs back because I discovered the source of my autoimmune carb aversion. It was the glycerol in the fish oil I was taking to supposedly improve my health.
Aldehydes are major carcinogens. Aldehydes are the body’s first step in metabolizing alcohol, fructose and other sugars. Most people have genetic catalysts which both neutralize aldehydes into vinegar and insert the remains into the Krebs energy cycle. These genetic catalysts are aldehyde dehydrogenases (ALDH’s). Many people have congenital mutations of ALDH’s which cause the aldehydes to persist in the system. I believe this is one of the main reasons why ketogenic diets work at preventing cancer.
https://www.mrc-cu.cam.ac.uk/news/AldehydesandCancer
Venison, wild game etc. is alkaline and not acidic like non-free-range. That might help.
The theory goes that if you add sugar or honey to the baking soda water the body is forced to work on the sugar, and the alkalinity bypasses the stomach acids.
Usually, keto diets start with no carbs for only two weeks, after that some carbs are added back in.
It was my understanding that the liver converted fat into glucose. Uric acid I understood was a byproduct of nitric oxide in the bloodstream. Nitric Oxide derived from l-arginine, which is commonly added to protein drinks. Not saying it doesn’t happen with too much protein though, that’s just all I know about it.
Wow, good on you for finding the cause. I got a sugar intolerance, sucrose intolerance I think, I just don’t know how I got it.
However, people who have deteriorated kidney function should avoid it.
Is a moderate LCHF diet (say 50-60 grams of carbohydrates per day) combined with intermittent fasting a viable alternative for these people?
The mutation is key. It’s a slow growing tumor. Strange case. Most of the people getting this tumor are young, in their 20’s or 30’s, not in their 70’s.
Fortunately for me I don't have to measure my protein intake but if I had reduced kidney function I would measure it and keep it at a low percentage of my total calories (maybe <30-40 grams a day). I would dramatically increase fats.
The health scenario you describe is a tough one. My brother was both diabetic and kidney impaired. Eventually it killed him.
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