Replies

A peer reviewed study published in the The National Center for Biotechnology Information, “Evaluation of transplacental Transfer of mRNA Vaccine Products and Functional Antibodies During Pregnancy and Infancy” concludes:

“To determine the transplacental transfer of mRNA vaccine-derived products, we examined available maternal blood at delivery, placenta tissue, and cord blood for Spike protein by western blot and vaccine mRNA by PCR. All available delivery samples (maternal blood, placental tissue, and cord blood) were negative for Spike protein by western blot (Supp Fig. 1, Supp Table 3) and did not have detectable levels of vaccine mRNA by PCR (Suppl Table 3). Together, this indicates that products of mRNA vaccination do not reach the fetus after vaccination during pregnancy at readily detectable levels.”

“Uptake of COVID-19 vaccination in pregnancy has been slow5, and reasons for vaccine hesitancy are likely multifactorial—but theoretical concerns that vaccine mRNA products could cross the placenta have been raised. We found no evidence of mRNA vaccine products in any of our delivery samples at readily detectable levels, consistent with a recent study that did not find evidence of mRNA vaccine-related Spike protein in placenta tissue by immunohistochemistry after maternal vaccination”31.

31. Santos A, et al. Absence of SARS-CoV-2 Spike glycoprotein expression in placentas from individuals after mRNA SARS-CoV-2 vaccination. Mod. Pathol. 2022 doi: 10.1038/s41379-022-01061-3. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

https://pubmed.ncbi.nlm.nih.gov/35908075/

Another peer reviewed study, from ScienceDirect:

“Minimal mRNA Uptake and Inflammatory Response to COVID-19 mRNA Vaccine Exposure in Human Placental Explants”

https://www.sciencedirect.com/science/article/pii/S2589004223016267

Conclusion:

“In conclusion, our results provide further support to published clinical research that COVID-19 vaccination during pregnancy was not associated with increased pregnancy complications or adverse neonatal outcomes.33,34 There have been no adverse histopathologic findings in placentas isolated from vaccinated pregnancies.35,36 Thus, our results provide additional reassurance regarding the safety of COVID-19 mRNA vaccines in pregnancy, which have been shown to protect both the mother and the baby against COVID-19 and associated complications.