If it’s the 5.2 or 6.1, lifter failure is a kmown issue.
The AFM/DFM - which I turned off on my 6.2 - has nothing to do with it.
My plan is the different cam and lifters with the delete kit. according to my mechanic he said the new lifters, pushrods etc will eliminate the problem. I hope he’s right, my previous vehicles i’ve never had this issue. The 5.3 apparently has the issue but it’s interesting that mine pops up after 100k miles, well outside warranty. My experience is better than other friends that have the same style silverado.