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Presence of specific lipids indicate tissue aging and can be decreased through exercise, study shows
Medical Xpress / Amsterdam University Medical Centers / Nature Aging ^ | April 12, 2024 | Georges Janssens et al

Posted on 04/20/2024 9:11:41 AM PDT by ConservativeMind

Scientists have discovered that a type of fat accumulates as tissue ages and that this accumulation can be reversed through exercise. Researchers analyzed both mice and human tissue before and after exercise allowing them to draw this conclusion.

"The idea that we could reverse aging is something that was long considered science fiction, but these findings do allow us to understand a lot more about the aging process," says Riekelt Houtkooper.

"Everyone says that 'it's just part of getting older,' but this doesn't actually have to be true," says Georges Janssens.

In recent years, laboratory research has shown that we may be able to counteract age-related diseases by intervening in the fundamental processes that lead to aging. Although science has increasingly mapped out how metabolism changes during aging, large parts remained uncharted.

"We wanted to add a new chapter to the atlas. Lipids are an important part of our diet, and crucial for the functioning of our body cells. Specific lipids make up the membrane of cells, which ensures that the inside and outside remain separate," says Houtkooper.

The research team investigated how the composition of fats changes in mice. They looked at ten different tissues, including muscles, kidneys, liver and heart. It was noticed that one type of lipid, the bis(monoacylglycero)phosphates (or BMPs), were elevated in all tissues from the older animals. Suggesting an accumulation of these lipids during aging. They then investigated whether this also happens in humans.

Although it was not possible to obtain as many different tissues, the accumulation of BMP was also visible in muscle biopsies of older people. Finally, they then completed more muscle biopsies from people before and after a healthy intervention that included one hour of exercise a day and saw the level of BMPs decreased in the active participants.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: bisphosphates; bmp
One hour of exercise of those muscles a day helped reduce bis(monoacylglycero)phosphates (BMPs) that had built up over the years, and may not be getting removed daily, as could have happened, when younger.
1 posted on 04/20/2024 9:11:41 AM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 04/20/2024 9:12:21 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Exer.cise is a double dose of four letter words


3 posted on 04/20/2024 9:40:18 AM PDT by faithhopecharity (“Politicians are not born. They're excreted.” Marcus Tillius Cicero (106 to 43 BCE))
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To: ConservativeMind

Thanks for posting. Makes sense since I believe high levels of bmp have been associated with cognitive decline and even Parkinsons. Is there a bis(monoacylglycero)phosphate blood or urine test ?


4 posted on 04/20/2024 11:46:11 AM PDT by erlayman (E )
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To: ConservativeMind

Can it be broken up into 2 half hours?


5 posted on 04/20/2024 7:55:38 PM PDT by KittyKares
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To: KittyKares

I would think it could.


6 posted on 04/20/2024 10:48:28 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: faithhopecharity

First they say you must be an active person and then top it off with an hour of daily exercise. A good life is not torturing my bones but sitting and reading a good book for an hour is a quality life.


7 posted on 04/21/2024 7:44:58 AM PDT by bgill (.)
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To: ConservativeMind

Thanks for doing this. A number of these articles have proven to be useful, both for me and for friends.


8 posted on 04/22/2024 12:19:27 PM PDT by sima_yi ( Reporting live from the far North)
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To: sima_yi
I care about all of you, but I can't give anyone money. I give each month to Free Republic, though.

However, getting truly cutting edge, actionable health study information out to people, well, that can be worth far more than money, anyway.

Even Medscape doesn't get to most of what I review and post, and Medscape is what doctors most read to get new health information. I get those same newsletters and compare, over subsequent weeks.

If these articles, always trimmed to 300 words, appeal to liberals, then that is also good. It never hurts to hear from conservatives, and we might sway a few to come over to our side.

Stay healthy, my friend. Strangely, it's easier to do, thanks to such breaking health news.

9 posted on 04/22/2024 12:50:43 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I would like to second that! Thank you for this wonderfully informative ping.
It has been incredibly helpful to many of my loved ones!
I am most grateful.


10 posted on 04/22/2024 3:20:19 PM PDT by acapesket (all happy now?)
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